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Scleroderma clinical trials in Chicago, IL

10 studies for Scleroderma are looking for participants at sites in and around Chicago (within about 30 miles). Open a study to see who can join and how to contact the study team.

A Study to Assess the Efficacy and Safety of Efgartigimod PH20 SC in Adults With Systemic Sclerosis

RecruitingPhase 2
  • University of Illinois Health Outpatient Care Center, Chicago
Ages 18 and older · All sexes · Updated Sep 24, 2026 · NCT06655155

A Study to Test Whether Nerandomilast Helps People With Systemic Sclerosis

RecruitingPhase 3
  • Northwestern University, Chicago
  • The University of Chicago Medical Center, Chicago
Ages 18 and older · All sexes · Updated Sep 17, 2026 · NCT07497087

A Study to Investigate the Safety and Preliminary Efficacy of ALLO-329, an Allogeneic CAR T-cell Therapy, in Adults With Autoimmune Disease

RecruitingPhase 1
  • The University of Chicago Medical Center, Chicago
Ages 18 to 74 · All sexes · Updated Sep 10, 2026 · NCT07085104

A Study of the Efficacy and Safety of Belimumab in Adults With Systemic Sclerosis Associated Interstitial Lung Disease

RecruitingPhase 2/3
  • GSK Investigational Site, Chicago
Ages 18 and older · All sexes · Updated Sep 8, 2026 · NCT05878717

A Safety and Efficacy Study Evaluating CTX112 in Adult Subjects With Refractory Autoimmune Disease

RecruitingPhase 1
  • Northwestern Medicine, Robert H. Lurie Comprehensive Cancer Center, Chicago
Ages 18 to 70 · All sexes · Updated Aug 28, 2026 · NCT06925542

Platform Clinical Study for Conquering Scleroderma

RecruitingPhase 2
  • The University of Chicago Medical Center (UCMC), Chicago
Ages 18 and older · All sexes · Updated Aug 18, 2026 · NCT06195072

RESET-SSc: An Open-Label Study to Evaluate the Safety and Efficacy of CABA-201, a CD19-CAR T Cell Therapy, in Subjects With Systemic Sclerosis

RecruitingPhase 2/3
  • Northwestern Memorial Hospital, Chicago
  • The University of Chicago Medical Center, Chicago
Ages 18 to 75 · All sexes · Updated Aug 17, 2026 · NCT06328777

A Phase 1/2 Study of NKX019 in Subjects With Immune-Mediated Diseases (Ntrust-2)

RecruitingPhase 1/2
  • Nkarta Investigational Site, Chicago
Ages 18 to 75 · All sexes · Updated Aug 7, 2026 · NCT06733935

A Study of AZD0120 in Autoimmune Diseases

RecruitingPhase 1
  • Research Site, Chicago
Ages 18 to 75 · All sexes · Updated Jul 28, 2026 · NCT07295847

Study to Evaluate the Efficacy, Safety, and Tolerability of Efzofitimod in Patients With Systemic Sclerosis (SSc)-Related Interstitial Lung Disease (ILD) (SSc-ILD)

RecruitingPhase 2
  • aTyr Investigative Site, Chicago
  • aTyr Investigative Site, Chicago
  • aTyr Investigative Site, Chicago
Ages 18 and older · All sexes · Updated May 7, 2025 · NCT05892614

About Scleroderma

Scleroderma is an autoimmune disease that causes inflammation and thickening in the skin and other areas of the body. The exact cause of scleroderma is unknown.

More about Scleroderma on MedlinePlus

Scleroderma trials in other cities

Other studies in Chicago

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.