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Scleroderma clinical trials in Durham, NC

7 studies for Scleroderma are looking for participants at sites in and around Durham (within about 30 miles). Open a study to see who can join and how to contact the study team.

A Study to Investigate the Safety and Preliminary Efficacy of ALLO-329, an Allogeneic CAR T-cell Therapy, in Adults With Autoimmune Disease

RecruitingPhase 1
  • Duke University Medical Center, Durham
Ages 18 to 74 · All sexes · Updated Sep 10, 2026 · NCT07085104

A Safety and Efficacy Study Evaluating CTX112 in Adult Subjects With Refractory Autoimmune Disease

RecruitingPhase 1
  • University of North Carolina TraCS Institute - CTRC, Chapel Hill · 10 mi away
Ages 18 to 70 · All sexes · Updated Aug 28, 2026 · NCT06925542

Platform Clinical Study for Conquering Scleroderma

RecruitingPhase 2
  • Duke University Medical Center, Durham
Ages 18 and older · All sexes · Updated Aug 18, 2026 · NCT06195072

RESET-SSc: An Open-Label Study to Evaluate the Safety and Efficacy of CABA-201, a CD19-CAR T Cell Therapy, in Subjects With Systemic Sclerosis

RecruitingPhase 2/3
  • Duke University, Durham
Ages 18 to 75 · All sexes · Updated Aug 17, 2026 · NCT06328777

A Study of AZD0120 in Autoimmune Diseases

RecruitingPhase 1
  • Research Site, Chapel Hill · 10 mi away
Ages 18 to 75 · All sexes · Updated Jul 28, 2026 · NCT07295847

A Study of Healthy Donor CD19-targeted Allogeneic CAR T Cells in Participants With Severe, Refractory Autoimmune Diseases

RecruitingPhase 1
  • Duke University, Durham
Ages 18 and older · All sexes · Updated Jul 14, 2026 · NCT07115745

A Phase 1 Study of FT819 in B-cell Mediated Autoimmune Disease

RecruitingPhase 1
  • Duke University Health System, Durham
Ages 12 to 70 · All sexes · Updated May 22, 2026 · NCT06308978

About Scleroderma

Scleroderma is an autoimmune disease that causes inflammation and thickening in the skin and other areas of the body. The exact cause of scleroderma is unknown.

More about Scleroderma on MedlinePlus

Scleroderma trials in other cities

Other studies in Durham

From ClinicalTrials.gov, data retrieved Sep 29, 2026. Each study sets its own eligibility; the study team decides who can join.