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Sickle Cell Disease clinical trials in Ohio
22 studies for Sickle Cell Disease are looking for participants at sites in Ohio.
Cities in Ohio
A Phase 1b, Open-Label Study of DISC-3405 in Participants With Sickle Cell Disease (SCD)
- Cincinnati Children's Hospital Medical Center, Cincinnati
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 23, 2026 · NCT07187973A Study to Evaluate How Well Etavopivat Works in People With Sickle Cell Disease
- Univ Hosp Cleveland Med Ctr, Cleveland
- Ohio State Univ Wexner Med Ctr, Columbus
RecruitingPhase 3
Ages 12 and older · All sexes · Updated Sep 17, 2026 · NCT06612268Sickle Cell Disease Biofluid Chip Technology (SCD BioChip)
- University Hospitals Case Medical Center, Cleveland
RecruitingObservational studyHealthy volunteers welcome
Ages 12 and older · All sexes · Updated Sep 11, 2026 · NCT02824471A Study to Evaluate BMS-986470 in Healthy Volunteers and Participants With Sickle Cell Disease
- Local Institution - 0028, Cleveland
RecruitingPhase 1/2Healthy volunteers welcome
Ages 18 and older · All sexes · Updated Aug 18, 2026 · NCT06481306ATHN Transcends: A Natural History Study of Non-Neoplastic Hematologic Disorders
- Akron Children's Hospital - Showers Center for Cancer & Blood Disorders, Akron
- Cincinnati Children's Hospital Medical Center, Hemophilia & Thrombosis Center, Cincinnati
- University of Cincinnati Medical Center Hemophilia Treatment Center, Cincinnati
- and 5 more
RecruitingObservational study
All ages · All sexes · Updated Aug 17, 2026 · NCT04398628Safety, Efficacy, and Pharmacokinetics of CSL889 in Adults and Adolescents With Sickle Cell Disease During Vaso-Occlusive Crisis
- University of Cincinnati, Cincinnati
- The Ohio State University, Columbus
RecruitingPhase 2
Ages 12 and older · All sexes · Updated Aug 14, 2026 · NCT06699849Integrative Medicine in Pain Management in Sickle Cell Disease, 2.0
- University of Cincinnati College of Medicine, Cincinnati
RecruitingHealthy volunteers welcome
Ages 14 to 80 · All sexes · Updated Aug 12, 2026 · NCT06725550Safety of Anumigilimab (CSL324) in Adults With Sickle Cell Disease (SCD)
- Ohio State University, Columbus
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Aug 5, 2026 · NCT07224360Gene Correction in Autologous CD34+ Hematopoietic Stem Cells (HbS to HbA) to Treat Severe Sickle Cell Disease
- Nationwide Children's Hospital, Columbus
RecruitingPhase 1/2
Ages 12 to 50 · All sexes · Updated Jul 2, 2026 · NCT04819841Hydroxyurea Exposure Limiting Pregnancy and Follow-Up Lactation
- Cincinnati Children's Hospital Medical Center, Cincinnati
RecruitingObservational study
All ages · All sexes · Updated Jun 18, 2026 · NCT04093986Comparing the Effectiveness of Matched Related Donor Hematopoietic Stem Cell Transplantation to Disease Modifying Therapy in Pediatric Patients With Sickle Cell Disease
- Nationwide Children's Hospital (NT-DMT), Columbus
RecruitingObservational study
Ages 3 to 20 · All sexes · Updated Jun 4, 2026 · NCT06941389A Socio-ecological Approach for Improving Self-management in Adolescents With SCD
- Cincinnati Children's Hospital Medical Center, Cincinnati
Recruiting
Ages 13 to 21 · All sexes · Updated May 11, 2026 · NCT06290401Delivering Patient-Facing Evidence-Based Guidelines Through mHealth to Adults With Sickle Cell Disease
- The Ohio State University Medical Center, Columbus
Recruiting
Ages 18 and older · All sexes · Updated Mar 23, 2026 · NCT06919224Zinc Supplementation in Sickle Cell Disease: A Precursor to the Think Zinc for Bones Trial
- Cincinnati Children's Hospital, Cincinnati
RecruitingPhase 2
Ages 15 to 40 · All sexes · Updated Mar 13, 2026 · NCT06260891Minimizing Toxicity in HLA-identical Sibling Donor Transplantation for Children With Sickle Cell Disease
- Nationwide Children's Hospital, Columbus
RecruitingPhase 2
Ages 2 to 25 · All sexes · Updated Mar 10, 2026 · NCT03587272MULTIsite Feasibility of MUSIc Therapy to Address Quality Of Life in Sickle Cell Disease
- UH Seidman Cancer Center Adult SCD Clinic or UH Rainbow Babies and Children's Hospital Sickle Cell Anemia Center, Cleveland
Recruiting
Ages 14 and older · All sexes · Updated Jan 29, 2026 · NCT06853158A Long-term Follow-up Study in Patients Who Received BEAM-101
- University Hospitals Clevland Medical Center, Cleveland
- The Clevland Clinic Foundation, Cleveland
RecruitingObservational study
Ages 14 to 37 · All sexes · Updated Jan 28, 2026 · NCT07373639Verifying Antibodies After Live Immunization Delivery (VALID): A Study of Measles Vaccine Immunogenicity in Children With Sickle Cell Disease
- Cincinnati Children's Hospital Medical Center, Cincinnati
RecruitingObservational study
6 Months – 6 Years · All sexes · Updated Jan 21, 2026 · NCT07356050Integrative Training Program for Pediatric Sickle Cell Pain
- Cincinnati Children's Hospital Medical Center, Cincinnati
Recruiting
Ages 12 to 18 · All sexes · Updated Nov 14, 2025 · NCT06691867Effectiveness of Nontraditional Hydroxyurea Algorithms: Novel and Clinical Evaluations (ENHANCE)
- Cincinnati Children's Hospital Medical Center, Cincinnati
RecruitingPhase 4
6 Months · All sexes · Updated Sep 16, 2025 · NCT07177300HPC Offered for PRESERVE Expansion
- The Ohio State University Medical Center, Columbus
RecruitingObservational study
Ages 12 to 80 · All sexes · Updated Aug 28, 2025 · NCT07145411Recruitment and Engagement in Care to Impact Practice Enhancement (RECIPE) for Sickle Cell Disease
- Cleveland Clinic, Cleveland
RecruitingObservational study
Ages 18 and older · All sexes · Updated Jun 22, 2025 · NCT06385886From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.