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Sickle Cell Disease clinical trials in Columbus, OH

9 studies for Sickle Cell Disease are looking for participants at sites in and around Columbus (within about 30 miles). Open a study to see who can join and how to contact the study team.

A Study to Evaluate How Well Etavopivat Works in People With Sickle Cell Disease

RecruitingPhase 3
  • Ohio State Univ Wexner Med Ctr, Columbus
Ages 12 and older · All sexes · Updated Sep 17, 2026 · NCT06612268

ATHN Transcends: A Natural History Study of Non-Neoplastic Hematologic Disorders

RecruitingObservational study
  • Ohio State University Medical Center, Columbus
  • Nationwide Children's Hospital Columbus, Columbus
All ages · All sexes · Updated Aug 17, 2026 · NCT04398628

Safety, Efficacy, and Pharmacokinetics of CSL889 in Adults and Adolescents With Sickle Cell Disease During Vaso-Occlusive Crisis

RecruitingPhase 2
  • The Ohio State University, Columbus
Ages 12 and older · All sexes · Updated Aug 14, 2026 · NCT06699849

Safety of Anumigilimab (CSL324) in Adults With Sickle Cell Disease (SCD)

RecruitingPhase 2
  • Ohio State University, Columbus
Ages 18 and older · All sexes · Updated Aug 5, 2026 · NCT07224360

Gene Correction in Autologous CD34+ Hematopoietic Stem Cells (HbS to HbA) to Treat Severe Sickle Cell Disease

RecruitingPhase 1/2
  • Nationwide Children's Hospital, Columbus
Ages 12 to 50 · All sexes · Updated Jul 2, 2026 · NCT04819841

Comparing the Effectiveness of Matched Related Donor Hematopoietic Stem Cell Transplantation to Disease Modifying Therapy in Pediatric Patients With Sickle Cell Disease

RecruitingObservational study
  • Nationwide Children's Hospital (NT-DMT), Columbus
Ages 3 to 20 · All sexes · Updated Jun 4, 2026 · NCT06941389

Delivering Patient-Facing Evidence-Based Guidelines Through mHealth to Adults With Sickle Cell Disease

Recruiting
  • The Ohio State University Medical Center, Columbus
Ages 18 and older · All sexes · Updated Mar 23, 2026 · NCT06919224

Minimizing Toxicity in HLA-identical Sibling Donor Transplantation for Children With Sickle Cell Disease

RecruitingPhase 2
  • Nationwide Children's Hospital, Columbus
Ages 2 to 25 · All sexes · Updated Mar 10, 2026 · NCT03587272

HPC Offered for PRESERVE Expansion

RecruitingObservational study
  • The Ohio State University Medical Center, Columbus
Ages 12 to 80 · All sexes · Updated Aug 28, 2025 · NCT07145411

About Sickle Cell Disease

Sickle cell disease is a group of inherited disorders that affect your red blood cells. It can cause pain, anemia, and other problems. Learn about treatments.

More about Sickle Cell Disease on MedlinePlus

Sickle Cell Disease trials in other cities

Other studies in Columbus

From ClinicalTrials.gov, data retrieved Oct 1, 2026. Each study sets its own eligibility; the study team decides who can join.