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Sickle Cell Disease clinical trials in Cincinnati, OH

10 studies for Sickle Cell Disease are looking for participants at sites in and around Cincinnati (within about 30 miles). Open a study to see who can join and how to contact the study team.

A Phase 1b, Open-Label Study of DISC-3405 in Participants With Sickle Cell Disease (SCD)

RecruitingPhase 1
  • Cincinnati Children's Hospital Medical Center, Cincinnati
Ages 18 and older · All sexes · Updated Sep 23, 2026 · NCT07187973

ATHN Transcends: A Natural History Study of Non-Neoplastic Hematologic Disorders

RecruitingObservational study
  • Cincinnati Children's Hospital Medical Center, Hemophilia & Thrombosis Center, Cincinnati
  • University of Cincinnati Medical Center Hemophilia Treatment Center, Cincinnati
All ages · All sexes · Updated Aug 17, 2026 · NCT04398628

Safety, Efficacy, and Pharmacokinetics of CSL889 in Adults and Adolescents With Sickle Cell Disease During Vaso-Occlusive Crisis

RecruitingPhase 2
  • University of Cincinnati, Cincinnati
Ages 12 and older · All sexes · Updated Aug 14, 2026 · NCT06699849

Integrative Medicine in Pain Management in Sickle Cell Disease, 2.0

RecruitingHealthy volunteers welcome
  • University of Cincinnati College of Medicine, Cincinnati
Ages 14 to 80 · All sexes · Updated Aug 12, 2026 · NCT06725550

Hydroxyurea Exposure Limiting Pregnancy and Follow-Up Lactation

RecruitingObservational study
  • Cincinnati Children's Hospital Medical Center, Cincinnati
All ages · All sexes · Updated Jun 18, 2026 · NCT04093986

A Socio-ecological Approach for Improving Self-management in Adolescents With SCD

Recruiting
  • Cincinnati Children's Hospital Medical Center, Cincinnati
Ages 13 to 21 · All sexes · Updated May 11, 2026 · NCT06290401

Zinc Supplementation in Sickle Cell Disease: A Precursor to the Think Zinc for Bones Trial

RecruitingPhase 2
  • Cincinnati Children's Hospital, Cincinnati
Ages 15 to 40 · All sexes · Updated Mar 13, 2026 · NCT06260891

Verifying Antibodies After Live Immunization Delivery (VALID): A Study of Measles Vaccine Immunogenicity in Children With Sickle Cell Disease

RecruitingObservational study
  • Cincinnati Children's Hospital Medical Center, Cincinnati
6 Months – 6 Years · All sexes · Updated Jan 21, 2026 · NCT07356050

Integrative Training Program for Pediatric Sickle Cell Pain

Recruiting
  • Cincinnati Children's Hospital Medical Center, Cincinnati
Ages 12 to 18 · All sexes · Updated Nov 14, 2025 · NCT06691867

Effectiveness of Nontraditional Hydroxyurea Algorithms: Novel and Clinical Evaluations (ENHANCE)

RecruitingPhase 4
  • Cincinnati Children's Hospital Medical Center, Cincinnati
6 Months · All sexes · Updated Sep 16, 2025 · NCT07177300

About Sickle Cell Disease

Sickle cell disease is a group of inherited disorders that affect your red blood cells. It can cause pain, anemia, and other problems. Learn about treatments.

More about Sickle Cell Disease on MedlinePlus

Sickle Cell Disease trials in other cities

Other studies in Cincinnati

From ClinicalTrials.gov, data retrieved Sep 29, 2026. Each study sets its own eligibility; the study team decides who can join.