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Colorectal Cancer clinical trials in Tyler, TX

8 studies for Colorectal Cancer are looking for participants at sites in and around Tyler (within about 30 miles). Open a study to see who can join and how to contact the study team.

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Study of Zanzalintinib in Combination With Immuno-Oncology or Other Agents in Participants With Solid Tumors

RecruitingPhase 1
  • Exelixis Clinical Site #70, Tyler
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT05176483

Symbiotic-GI-03: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Metastatic Colorectal Cancer

RecruitingPhase 3
  • Texas Oncology - Northeast Texas, Tyler
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07222800

A Study of Amivantamab and FOLFIRI Versus Cetuximab/Bevacizumab and FOLFIRI in Participants With KRAS/NRAS and BRAF Wild-type Colorectal Cancer Who Have Previously Received Chemotherapy

RecruitingPhase 3
  • UT Health East Texas HOPE Cancer Center, Tyler
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06750094

Phase III Study of Ivonescimab or Bevacizumab Combined With FOLFOX in Patients With Metastatic Colorectal Cancer

RecruitingPhase 3
  • Clinical Study Site, Tyler
Ages 18 and older · All sexes · Updated Sep 8, 2026 · NCT07228832

A Study of ERAS-0015 in Patients With Advanced or Metastatic Solid Tumors

RecruitingPhase 1
  • University of Texas at Tyler, Tyler
Ages 18 to 99 · All sexes · Updated Sep 1, 2026 · NCT06983743

A Study of Bispecific Antibody MCLA-158 in Patients With Advanced Solid Tumors

RecruitingPhase 1/2
  • Texas Oncology, Tyler
Ages 18 and older · All sexes · Updated Jul 29, 2026 · NCT03526835

A Study of Fruquintinib Plus FOLFIRI as Second-Line Treatment for Participants With Metastatic Colorectal Cancer (FRUITFUL)

RecruitingPhase 2
  • Texas Oncology - Northeast Texas, Tyler
Ages 18 and older · All sexes · Updated Jun 12, 2026 · NCT07011576

About Colorectal Cancer

Colorectal cancer starts in the colon or rectum. It may not cause symptoms at first. Screening tests can help find it early, when treatment is most effective.

More about Colorectal Cancer on MedlinePlus

Colorectal Cancer trials in other cities

Other studies in Tyler

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.