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Diffuse Intrinsic Pontine Glioma clinical trials in Philadelphia, PA

10 studies for Diffuse Intrinsic Pontine Glioma are looking for participants at sites in and around Philadelphia (within about 30 miles). Open a study to see who can join and how to contact the study team.

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CBL0137 for the Treatment of Relapsed or Refractory Solid Tumors, Including CNS Tumors and Lymphoma

RecruitingPhase 1/2
  • Children's Hospital of Philadelphia, Philadelphia
12 Months – 21 Years · All sexes · Updated Sep 11, 2026 · NCT04870944

Targeted Pediatric High-Grade Glioma Therapy

RecruitingObservational study
  • Children's Hospital of Philadelphia, Philadelphia
12 Months – 39 Years · All sexes · Updated Sep 8, 2026 · NCT05839379

Study of Olutasidenib and Temozolomide in HGG

RecruitingPhase 2
  • Children's Hospital of Philadelphia, Philadelphia
Ages 12 to 39 · All sexes · Updated Sep 1, 2026 · NCT06161974

PEP-CMV Vaccine Targeting CMV Antigen to Treat Newly Diagnosed Pediatric HGG and DIPG and Recurrent Medulloblastoma

RecruitingPhase 2
  • Children's Hospital of Philadelphia, Philadelphia
Ages 3 to 39 · All sexes · Updated Aug 24, 2026 · NCT05096481

Illuminate: A Clinical Study Evaluating CAR T Immune Cell Therapy (BCB-276) for Patients With Diffuse Intrinsic Pontine Glioma (DIPG).

RecruitingPhase 2
  • Children's Hospital of Philadelphia, Philadelphia
Ages 1 to 26 · All sexes · Updated Aug 4, 2026 · NCT07680439

Lutathera for Treatment of Recurrent or Progressive High-Grade CNS Tumors

RecruitingPhase 1/2
  • Children's Hospital of Philadelphia, Philadelphia
Ages 4 to 39 · All sexes · Updated Jul 20, 2026 · NCT05278208

Lorlatinib for Newly-Diagnosed High-Grade Glioma With ROS or ALK Fusion

RecruitingEarly phase 1Healthy volunteers welcome
  • Children's Hospital of Philadelphia, Philadelphia
Ages 1 to 21 · All sexes · Updated Jun 29, 2026 · NCT06333899

Combination Therapy for the Treatment of Diffuse Midline Gliomas

RecruitingPhase 2
  • Children's Hospital of Philadelphia, Philadelphia
Ages 2 to 39 · All sexes · Updated Jun 26, 2026 · NCT05009992

Study of Ribociclib and Everolimus in HGG and DIPG or Ribociclib and Temozolomide in DHG, H3G34-mutant

RecruitingPhase 2
  • Children's Hospital of Philadelphia, Philadelphia
12 Months – 39 Years · All sexes · Updated May 29, 2026 · NCT05843253

A Pilot Study of Larotrectinib for Newly-Diagnosed High-Grade Glioma With NTRK Fusion

RecruitingEarly phase 1
  • Children's Hospital of Philadelphia, Philadelphia
Up to age 21 · All sexes · Updated Mar 18, 2026 · NCT04655404

Diffuse Intrinsic Pontine Glioma trials in other cities

Other studies in Philadelphia

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.