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Endometrial Cancer clinical trials in Pittsburgh, PA

23 studies for Endometrial Cancer are looking for participants at sites in and around Pittsburgh (within about 30 miles). Open a study to see who can join and how to contact the study team.

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Testing the Addition of an Antiangiogenic Drug (Bevacizumab) to Chemotherapy (Carboplatin and Paclitaxel) Combined With Immunotherapy (Pembrolizumab) for pMMR, TP53 Mutated Endometrial Cancer

RecruitingPhase 3
  • UPMC-Magee Womens Hospital, Pittsburgh
  • UPMC-Passavant Hospital, Pittsburgh
  • UPMC Cancer Center-Washington, Washington · 23 mi away
  • and 1 more
Ages 18 and older · Women · Updated Oct 5, 2026 · NCT07198074

Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Advanced Solid Tumors, The ComboMATCH Screening Trial

RecruitingPhase 2
  • UPMC-Magee Womens Hospital, Pittsburgh
  • UPMC Hillman Cancer Center, Pittsburgh
  • UPMC-Passavant Hospital, Pittsburgh
  • and 3 more
All ages · All sexes · Updated Oct 5, 2026 · NCT05564377

The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)

RecruitingPhase 1/2
  • University of Pittsburgh Medical Center, Pittsburgh
Ages 12 and older · All sexes · Updated Oct 2, 2026 · NCT04585750

A Phase 1 Study of the Safety and Tolerability of CTX-10726

RecruitingPhase 1
  • UPMC Hillman Cancer Center, Pittsburgh
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT07419841

Distance-Based Exercise to Preserve Function and Prevent Disability

Recruiting
  • UPMC Hillman Cancer Center, Pittsburgh
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT07059884

Testing Nivolumab With or Without Ipilimumab in Deficient Mismatch Repair System (dMMR) Recurrent Endometrial Carcinoma

RecruitingPhase 2
  • UPMC-Magee Womens Hospital, Pittsburgh
  • UPMC-Saint Margaret, Pittsburgh
  • UPMC-Mercy Hospital, Pittsburgh
  • and 12 more
Ages 18 and older · Women · Updated Sep 28, 2026 · NCT05112601

Phase 1 Study to Investigate TCRTs KRAS Mutation in Unresectable, Advanced, and/or Metastatic Solid Tumors

RecruitingPhase 1
  • Research Site, Pittsburgh
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06218914

A Study of LY4257496 in Participants With Cancer (OMNIRAY)

RecruitingPhase 1
  • University of Pittsburgh Medical Center, Pittsburgh
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07114601

Study of Elironrasib and Daraxonrasib as Monotherapies and Combination Therapy in Participants With Advanced KRAS G12C Mutant Solid Tumors

RecruitingPhase 1/2
  • Allegheny Health Network, Pittsburgh
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT06128551

A Phase I/IIa Study of AZD8205 Given Alone or Combined, in Participants With Advanced/Metastatic Solid Malignancies

RecruitingPhase 1/2
  • Research Site, Pittsburgh
Ages 18 and older · All sexes · Updated Sep 11, 2026 · NCT05123482

Phase 1, Safety and Tolerability Study of XmAb541 in Advanced Solid Tumors

RecruitingPhase 1
  • UPMC Hillman Cancer Center, Pittsburgh
Ages 15 and older · All sexes · Updated Aug 25, 2026 · NCT06276491

Tegavivint for the Treatment of Recurrent or Refractory Solid Tumors, Including Lymphomas and Desmoid Tumors

RecruitingPhase 1/2
  • Children's Hospital of Pittsburgh of UPMC, Pittsburgh
12 Months – 30 Years · All sexes · Updated Aug 25, 2026 · NCT04851119

A Phase 2 Study of ACR-368 in Endometrial Adenocarcinoma

RecruitingPhase 2
  • West Penn Hospital, Pittsburgh
Ages 18 and older · Women · Updated Aug 21, 2026 · NCT05548296

A Phase 1 Study of LNCB74 in Advanced Solid Tumors

RecruitingPhase 1
  • UPMC, Pittsburgh
Ages 18 and older · All sexes · Updated Aug 21, 2026 · NCT06774963

FOG-001 in Locally Advanced or Metastatic Solid Tumors

RecruitingPhase 1/2
  • University of Pittsburgh Medical Center, Hillman Cancer Center, Pittsburgh
Ages 18 and older · All sexes · Updated Aug 17, 2026 · NCT05919264

Rinatabart Sesutecan (Rina-S, PRO1184, GEN1184) for Advanced Solid Tumors (GCT1184-01/ PRO1184-001)

RecruitingPhase 1/2
  • Allegheny Health Network, Pittsburgh
Ages 18 and older · All sexes · Updated Aug 4, 2026 · NCT05579366

Puxitatug Samrotecan (AZD8205) Monotherapy vs Chemotherapy in B7-H4-selected Endometrial Cancer (Bluestar-Endometrial01)

RecruitingPhase 3
  • Research Site, Pittsburgh
  • Research Site, Pittsburgh
Ages 18 and older · Women · Updated Jul 29, 2026 · NCT07044336

Relacorilant in Combination With Different Treatment Regimens in Patients With Gynecological Cancers

RecruitingPhase 2
  • 127, Pittsburgh
Ages 18 and older · Women · Updated Jul 16, 2026 · NCT06906341

A Study of Lorigerlimab in Participants With Advanced Solid Tumors

RecruitingPhase 2
  • West Penn Allegheny Health, Pittsburgh
Ages 18 and older · Women · Updated Jun 2, 2026 · NCT06730347

Sapanisertib and Serabelisib (PIKTOR) With Paclitaxel and a Substudy With an Insulin-Suppressing Diet in Patients With Advanced/Recurrent Endometrial Cancer

RecruitingPhase 2
  • West Penn Hospital, Pittsburgh
Ages 18 and older · Women · Updated Dec 24, 2025 · NCT06463028

A Study of Lifileucel (Tumor-infiltrating Lymphocytes) in Adults With Advanced Endometrial Cancer.

RecruitingPhase 2
  • Allegheny Health, Pittsburgh
Ages 18 to 70 · Women · Updated Oct 30, 2025 · NCT06481592

Endometrial Cancer trials in other cities

Other studies in Pittsburgh

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.