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Metastatic Cancer clinical trials in Arlington, VA

53 studies for Metastatic Cancer are looking for participants at sites in and around Arlington (within about 30 miles). Open a study to see who can join and how to contact the study team.

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Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Advanced Solid Tumors, The ComboMATCH Screening Trial

RecruitingPhase 2
  • Inova Fairfax Hospital, Falls Church · 4 mi away
  • Inova Schar Cancer Institute, Fairfax · 11 mi away
All ages · All sexes · Updated Oct 2, 2026 · NCT05564377

The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)

RecruitingPhase 1/2
  • Virginia Cancer Specialists, Fairfax · 11 mi away
Ages 12 and older · All sexes · Updated Oct 2, 2026 · NCT04585750

Atebimetinib + GnP as a First Line Treatment in Patients With Metastatic Pancreatic Adenocarcinoma

RecruitingPhase 3
  • Virginia Cancer Specialists, Fairfax · 11 mi away
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT07562152

A Phase 1 Study of PLN-101095 in Adults With Advanced or Metastatic Solid Tumors

RecruitingPhase 1
  • Inova Schar Cancer Institute, Fairfax · 11 mi away
  • NEXT Virginia, Fairfax · 11 mi away
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT06270706

A Study of HC-7366 in Combination With Belzutifan (WELIREG™) in Patients With Renal Cell Carcinoma

RecruitingPhase 1
  • Virginia Cancer Specialists, Fairfax · 11 mi away
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT06234605

A Study With NKT3964 for Adults With Advanced/Metastatic Solid Tumors

RecruitingPhase 1
  • NEXT Virginia, Fairfax · 11 mi away
Ages 19 and older · All sexes · Updated Oct 1, 2026 · NCT06586957

A First in Human Study of ALX2004 With Advanced or Metastatic Selected Solid Tumors

RecruitingPhase 1
  • ALX Center 2, Fairfax · 11 mi away
Ages 18 and older · All sexes · Updated Sep 30, 2026 · NCT07085091

A Study of ASP3082 in Adults With Advanced Solid Tumors

RecruitingPhase 1
  • NEXT Oncology - Virginia Cancer Specialists, Fairfax · 11 mi away
Ages 18 and older · All sexes · Updated Sep 30, 2026 · NCT05382559

Zanzalintinib Versus Everolimus in Participants With Locally Advanced or Metastatic Neuroendocrine Tumors

RecruitingPhase 2/3
  • Virginia Cancer Specialists - Fairfax Office, Fairfax · 11 mi away
Ages 18 and older · All sexes · Updated Sep 29, 2026 · NCT06943755

Symbiotic-GI-03: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Metastatic Colorectal Cancer

RecruitingPhase 3
  • Virginia Cancer Specialists, PC, Arlington
  • Virginia Cancer Specialists, PC, Fairfax · 11 mi away
  • Virginia Cancer Specialists, PC, Reston · 14 mi away
  • and 1 more
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07222800

A Study of IDE892 as Monotherapy and Combination in MTAP-deleted Advanced Solid Tumors

RecruitingPhase 1
  • NEXT Oncology Virginia, Fairfax · 11 mi away
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07277413

A Study of NEOK001, a B7-H3 and ROR1 Targeting Bispecific ADC in Participants With Select Solid Tumors

RecruitingPhase 1
  • NEXT Oncology, Fairfax · 11 mi away
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT07612176

ASPEN-09-03: A Study of Evorpacept in Combination With Trastuzumab and Chemotherapy in Metastatic HER2-Positive Breast Cancer

RecruitingPhase 2
  • Virginia Cancer Specialists, Fairfax · 11 mi away
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT07007559

A Study of Zidesamtinib (NVL-520) in Patients With Advanced NSCLC and Other Solid Tumors Harboring ROS1 Rearrangement (ARROS-1)

RecruitingPhase 1/2
  • NEXT Oncology - Virginia Cancer Specialists, Fairfax · 11 mi away
Ages 12 and older · All sexes · Updated Sep 24, 2026 · NCT05118789

A Study of Tersolisib (LY4064809/STX-478) With Other Anti-Cancer Treatments in Participants With Advanced Breast Cancer With a Genetic Change (PIK3CA)

RecruitingPhase 3
  • Virginia Cancer Specialists, Fairfax · 11 mi away
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07174336

Study of Elironrasib and Daraxonrasib as Monotherapies and Combination Therapy in Participants With Advanced KRAS G12C Mutant Solid Tumors

RecruitingPhase 1/2
  • NEXT Oncology Virginia, Fairfax · 11 mi away
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT06128551

A First-in-Human Trial of BLU-924 (SAR449336) in Advanced Solid Tumors Harboring KRAS Mutations

RecruitingPhase 1/2
  • Next Oncology Virginia Cancer Specialist, Fairfax · 11 mi away
Ages 18 and older · All sexes · Updated Sep 21, 2026 · NCT07629960

Symbiotic-GU-08: A Study to Learn About the Medicine Called PF-08634404 Dosed Alone and in Combination With Other Anticancer Therapies in Adults With Locally Advanced or Metastatic Renal Cell Cancer

RecruitingPhase 1/2
  • Virginia Cancer Specialists, PC, Fairfax · 11 mi away
Ages 18 and older · All sexes · Updated Sep 17, 2026 · NCT07227415

A Study to Evaluate Safety, Tolerability and Preliminary Activity of AGX101 in Participants With Advanced Solid Tumors

RecruitingPhase 1
  • NEXT Oncology, Fairfax · 11 mi away
Ages 18 and older · All sexes · Updated Sep 9, 2026 · NCT06440005

NPX372, a B7-H7:CD3 Bispecific Antibody, in Selected Solid Tumor Malignancies

RecruitingPhase 1
  • NEXT, Fairfax · 11 mi away
Ages 19 and older · All sexes · Updated Sep 8, 2026 · NCT07563829

A Study of First-Line Olomorasib (LY3537982) and Pembrolizumab With or Without Chemotherapy in Patients With Advanced KRAS G12C-Mutant Non-small Cell Lung Cancer

RecruitingPhase 3
  • USO - Virginia Cancer Specialists, Fairfax · 11 mi away
Ages 18 and older · All sexes · Updated Sep 8, 2026 · NCT06119581

A Study of LY4050784 in Participants With Advanced or Metastatic Solid Tumors

RecruitingPhase 1
  • USO-Virginia Cancer Specialists, PC, Fairfax · 11 mi away
Ages 18 and older · All sexes · Updated Sep 8, 2026 · NCT06561685

AVENTINE-1: Study of AVZO-1418 as a Single Agent and in Combination Therapy in Patients With Locally Advanced or Metastatic Solid Tumors (AVZO-1418-1001)

RecruitingPhase 1/2
  • Avenzo Therapeutics Recruiting Site, Fairfax · 11 mi away
Ages 18 to 75 · All sexes · Updated Sep 4, 2026 · NCT07038343

A Study to Evaluate KIN-2787 in Participants With BRAF and/or NRAS Mutation Positive Solid Tumors

RecruitingPhase 1
  • Virginia Cancer Specialists, Fairfax · 11 mi away
Ages 18 and older · All sexes · Updated Sep 2, 2026 · NCT04913285

A Study of ERAS-0015 in Patients With Advanced or Metastatic Solid Tumors

RecruitingPhase 1
  • NEXT Virginia, Fairfax · 11 mi away
Ages 18 to 99 · All sexes · Updated Sep 1, 2026 · NCT06983743

A Study With NKT5097 for Adults With Advanced/Metastatic Solid Tumors

RecruitingPhase 1
  • NEXT Virginia, Fairfax · 11 mi away
Ages 18 and older · All sexes · Updated Aug 28, 2026 · NCT07029399

A Study to See if Giving Fianlimab and Cemiplimab Together is Better Than Cemiplimab Alone at Treating Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma

RecruitingPhase 2
  • Inova Schar Cancer Institute, Fairfax · 11 mi away
Ages 18 and older · All sexes · Updated Aug 21, 2026 · NCT06769698

A Study to Investigate Safety and Effectiveness of CRN09682 in Participants With SST2-Expressing NENs and Other Solid Tumors

RecruitingPhase 1/2
  • Crinetics Study Site, Fairfax · 11 mi away
Ages 18 and older · All sexes · Updated Jul 31, 2026 · NCT07129252

A Study of ART0380 for the Treatment of Advanced or Metastatic Solid Tumors

RecruitingPhase 1/2
  • Virginia Cancer Specialists, Fairfax · 11 mi away
Ages 18 and older · All sexes · Updated Jul 30, 2026 · NCT04657068

Puxitatug Samrotecan (AZD8205) Monotherapy vs Chemotherapy in B7-H4-selected Endometrial Cancer (Bluestar-Endometrial01)

RecruitingPhase 3
  • Research Site, Falls Church · 4 mi away
  • Research Site, Fairfax · 11 mi away
Ages 18 and older · Women · Updated Jul 29, 2026 · NCT07044336

A Study of ASP1002 in Adults for Treatment of Solid Tumors

RecruitingPhase 1
  • NEXT Oncology Virginia, Fairfax · 11 mi away
Ages 18 and older · All sexes · Updated Jul 23, 2026 · NCT05719558

A Study of CHS-114 (Tagmokitug) in Combination With Toripalimab and/or Other Treatments in Participants With Advanced Solid Tumors

RecruitingPhase 1
  • Virginia Cancer Specialists, Fairfax · 11 mi away
Ages 18 and older · All sexes · Updated Jul 15, 2026 · NCT06657144

A Study of PYX-201 in Advanced Solid Tumors

RecruitingPhase 1
  • NEXT Virginia, Fairfax · 11 mi away
Ages 18 and older · All sexes · Updated Jun 30, 2026 · NCT05720117

A Phase 1 Dose-escalation Trial of KST-6051 in Participants With Advanced Solid Tumors With Kirsten Rat Sarcoma Viral Oncogene Homolog (KRAS) Mutation

RecruitingPhase 1
  • NEXT Virginia, Fairfax · 11 mi away
Ages 18 and older · All sexes · Updated Jun 29, 2026 · NCT07458347

A Study of LY4175408 in Participants With Advanced Cancer

RecruitingPhase 1
  • NEXT Virginia, Fairfax · 11 mi away
Ages 18 and older · All sexes · Updated Jun 23, 2026 · NCT07046923

First-in-Human Study of PLX-61639 in Locally Advanced or Metastatic Solid Tumors

RecruitingPhase 1
  • Research Site, Fairfax · 11 mi away
Ages 18 and older · All sexes · Updated Jun 12, 2026 · NCT07284186

A Study to Learn About Study Medicine ALTA3263 in Adults With Advanced Solid Tumors With KRAS Mutations

RecruitingPhase 1
  • Research Site, Fairfax · 11 mi away
Ages 18 and older · All sexes · Updated Jun 10, 2026 · NCT06835569

Study of RMC-9805 in Participants With KRAS G12D-Mutant Solid Tumors

RecruitingPhase 1
  • NEXT Oncology Virginia, Fairfax · 11 mi away
Ages 18 and older · All sexes · Updated Jun 3, 2026 · NCT06040541

Dose Escalation/Expansion Study of Mavrostobart (PT199), an Anti-CD73 mAb, Administered Alone and in Combination With a PD-1 Inhibitor or Chemotherapy (the MORNINGSTAR Study)

RecruitingPhase 1/2
  • NEXT Oncology, Fairfax · 11 mi away
Ages 18 and older · All sexes · Updated May 19, 2026 · NCT05431270

A Study to Find a Suitable Dose of ASP5834 in Adults With Solid Tumors

RecruitingPhase 1
  • NEXT Oncology Virginia, Fairfax · 11 mi away
Ages 18 and older · All sexes · Updated May 18, 2026 · NCT07094204

Study of RMC-6236 in Patients With Advanced Solid Tumors Harboring Specific Mutations in RAS

RecruitingPhase 1/2
  • Next Oncology Virginia, Fairfax · 11 mi away
Ages 18 and older · All sexes · Updated May 15, 2026 · NCT05379985

A Phase 1/2 Study of VS-7375 in Patients With KRAS G12D-Mutated Solid Tumors

RecruitingPhase 1/2
  • Virginia Cancer Specialists, Fairfax · 11 mi away
Ages 18 and older · All sexes · Updated Apr 22, 2026 · NCT07020221

Placebo-Controlled Trial of IFx-Hu2.0 Followed By Pembrolizumab In Checkpoint Inhibitor Naïve Participants With Advanced Or Metastatic Merkel Cell Carcinoma

RecruitingPhase 2/3
  • Inova Schar Cancer, Fairfax · 11 mi away
Ages 18 and older · All sexes · Updated Apr 17, 2026 · NCT06947928

A Phase 1 Study of CPO301 in Adult Patients With Advanced or Metastatic Solid Tumors

RecruitingPhase 1
  • NEXT Virginia, Fairfax · 11 mi away
Ages 18 and older · All sexes · Updated Mar 20, 2026 · NCT05948865

A Study Evaluating FMC-376 in Participants With KRAS G12C Mutated Solid Tumors

RecruitingPhase 1/2
  • Virginia Cancer Specialists, Fairfax · 11 mi away
Ages 18 and older · All sexes · Updated Mar 18, 2026 · NCT06244771

A Study of NVL-330 in Patients With Advanced or Metastatic HER2-altered NSCLC (HEROEX-1)

RecruitingPhase 1
  • NEXT Virginia, Fairfax · 11 mi away
Ages 18 and older · All sexes · Updated Feb 25, 2026 · NCT06521554

Study of CP-383 in Patients With Advanced or Metastatic Solid Tumors

RecruitingPhase 1/2
  • NEXT Virginia, Fairfax · 11 mi away
Ages 18 and older · All sexes · Updated Feb 18, 2026 · NCT07030257

Evaluation of RBS2418 in Subjects With Advanced, Metastatic Solid Tumors

RecruitingPhase 1
  • NEXT Virigina, Fairfax · 11 mi away
Ages 18 and older · All sexes · Updated Dec 19, 2025 · NCT05270213

Phase 1 Study Evaluating the Safety and PK of ADU-1805 in Advanced Solid Tumors

RecruitingPhase 1
  • Virginia Cancer Specialists, Fairfax · 11 mi away
Ages 18 and older · All sexes · Updated Dec 17, 2025 · NCT05856981

JZP898 Intravenous Infusion as Monotherapy and Combination With Pembrolizumab in Adults With Advanced/Metastatic Solid Tumors

RecruitingPhase 1
  • Virginia Cancer Specialists, Fairfax · 11 mi away
Ages 18 and older · All sexes · Updated Dec 16, 2025 · NCT06108050

A Study of OR502, a Monoclonal Antibody Targeting LILRB2, Alone and in Combination With Anticancer Agents

RecruitingPhase 1/2
  • NEXT Virginia, Fairfax · 11 mi away
Ages 18 and older · All sexes · Updated Jan 7, 2025 · NCT06090266

Metastatic Cancer trials in other cities

Other studies in Arlington

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.