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Esophageal Cancer clinical trials in Durham, NC

10 studies for Esophageal Cancer are looking for participants at sites in and around Durham (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

The Vanguard Study: Testing a New Way to Screen for Cancer

RecruitingHealthy volunteers welcome
  • Durham VA Medical Center, Durham
  • UNC Lineberger Comprehensive Cancer Center, Chapel Hill · 10 mi away
Ages 45 to 75 · All sexes · Updated Oct 5, 2026 · NCT06995898

Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection

RecruitingObservational studyHealthy volunteers welcome
  • Durham VA Medical Center, Durham
Ages 40 to 75 · All sexes · Updated Oct 2, 2026 · NCT05334069

Upfront Chemotherapy With Radiation Therapy (CRT) Followed by Chemotherapy in Localized Esophageal Adenocarcinoma

RecruitingPhase 2
  • Duke University Medical Center, Durham
Ages 18 and older · All sexes · Updated Sep 29, 2026 · NCT07603375

DESTINY-PANTUMOUR04

RecruitingObservational study
  • Research Site, Durham
Ages 18 to 130 · All sexes · Updated Sep 25, 2026 · NCT07124000

A Study of LY4337713 in Participants With FAP-Positive Solid Tumors

RecruitingPhase 1
  • Duke University Medical Center, Durham
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07213791

Pharmacologic Therapies to Mitigate Radiation- Associated Heart Disease

RecruitingPhase 2
  • Lineberger Comprehensive Cancer Center at University of North Carolina, Chapel Hill, Chapel Hill · 10 mi away
Ages 18 and older · All sexes · Updated Sep 17, 2026 · NCT07685938

ORACLE: Observation of ResiduAl Cancer With Liquid Biopsy Evaluation

RecruitingObservational study
  • UNC- Chapel Hill, Chapel Hill · 10 mi away
Ages 18 and older · All sexes · Updated Sep 14, 2026 · NCT05059444

Genetic Determinants of Barrett's Esophagus and Esophageal Adenocarcinoma

RecruitingObservational studyHealthy volunteers welcome
  • University of North Carolina at Chapel Hill, Chapel Hill · 10 mi away
Ages 18 and older · All sexes · Updated Aug 10, 2026 · NCT00288119

SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

RecruitingObservational study
  • Massive Bio SYNERGY-AI site, Chapel Hill · 10 mi away
All ages · All sexes · Updated Oct 28, 2025 · NCT03452774

About Esophageal Cancer

Early esophageal cancer does not have symptoms. Factors that increase risk include heavy drinking and smoking. Learn how you can reduce your risk.

More about Esophageal Cancer on MedlinePlus

Esophageal Cancer trials in other cities

Other studies in Durham

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.