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Head and Neck Cancer clinical trials in Los Angeles, CA

10 studies for Head and Neck Cancer are looking for participants at sites in and around Los Angeles (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)

RecruitingPhase 1/2
  • UCLA Jonsson Comprehensive Cancer Center, Los Angeles
  • USC Norris Comprehensive Cancer Center, Los Angeles
Ages 12 and older · All sexes · Updated Oct 2, 2026 · NCT04585750

FORTIFI-HN01: A Study of Ficerafusp Alfa (BCA101) or Placebo in Combination With Pembrolizumab in First-Line PD-L1-pos, R or M HNSCC

RecruitingPhase 2/3
  • Site #0106, Los Angeles
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT06788990

A Study to Learn About the Study Medicine Called PF-08046876 in People With Advanced Solid Tumors

RecruitingPhase 1
  • Ronald Reagan UCLA Medical Center, Los Angeles
  • UCLA Department of Medicine-Hematology/Oncology, Los Angeles
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT07090499

Intratumoral N17350 in Advanced Solid Tumors

RecruitingPhase 1/2
  • The Angeles Clinic and Research Institute, Los Angeles
  • UCLA - Jonsson Comprehensive Cancer Center, Los Angeles
Ages 18 and older · All sexes · Updated Sep 23, 2026 · NCT07339176

A Phase 1 Study of EPI-326 in EGFR-mutant NSCLC and HNSCC

RecruitingPhase 1
  • Site 105 - START Los Angeles, Los Angeles
Ages 18 and older · All sexes · Updated Sep 10, 2026 · NCT07462377

Study of INBRX-106 and INBRX-106 in Combination With Pembrolizumab (Keytruda®) in Subjects With Locally Advanced or Metastatic Solid Tumors (Hexavalent OX40 Agonist)

RecruitingPhase 1/2
  • California Research Institute, Los Angeles
  • Valkyrie Clinical Trials, Los Angeles
Ages 18 and older · All sexes · Updated Jul 29, 2026 · NCT04198766

First-in-Human Study of Tersolisib (STX-478) as Monotherapy and in Combination With Other Antineoplastic Agents in Participants With Advanced Solid Tumors

RecruitingPhase 1/2
  • Ellison Clinic at Saint John's, Los Angeles
Ages 18 and older · All sexes · Updated Jul 7, 2026 · NCT05768139

A Study of Dostarlimab vs Placebo After Chemoradiation in Adult Participants With Locally Advanced Unresected Head and Neck Squamous Cell Carcinoma

RecruitingPhase 3
  • GSK Investigational Site, Los Angeles
Ages 18 and older · All sexes · Updated May 26, 2026 · NCT06256588

A Study to Evaluate TROP2 ADC LCB84 Single Agent and in Combination With an Anti-PD-1 Ab in Advanced Solid Tumors

RecruitingPhase 1/2
  • Cedars Sinai Medical Center, Los Angeles
Ages 18 and older · All sexes · Updated Sep 24, 2025 · NCT05941507

Study of Safety and Tolerability of BCA101 Monotherapy and in Combination Therapy in Patients With EGFR-driven Advanced Solid Tumors

RecruitingPhase 1
  • Keck School of Medicine of USC, Los Angeles
  • UCLA, Los Angeles
Ages 18 and older · All sexes · Updated Aug 15, 2025 · NCT04429542

About Head and Neck Cancer

Head and neck cancer includes cancers of the mouth, nose, sinuses, salivary glands, throat, and lymph nodes. Read the different symptoms of each type.

More about Head and Neck Cancer on MedlinePlus

Head and Neck Cancer trials in other cities

Other studies in Los Angeles

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.