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Healthy volunteer studies in Louisville, KY

31 studies at sites in and around Louisville accept healthy volunteers — people without the condition being studied. Many studies pay participants for their time and travel; the amount is set by each study, so ask the study team.

A Clinical Study of Novel Pneumococcal Vaccine V118C in Children (V118C-002)

RecruitingPhase 1Healthy volunteers welcome
  • University of Louisville, Norton Children's Research Institute ( Site 1005), Louisville
2 Months – 15 Months · All sexes · Updated Oct 2, 2026 · NCT07300267

Observational Study of Decentralized Urine Optical Interaction Patterns Associated With Environmental Microplastic and Nanoplastic Exposure

RecruitingObservational studyHealthy volunteers welcome
  • Decentralized / At-Home Participation (U.S.), Louisville
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT07775495

Study of XmAb942 in Healthy Participants and Participants With Ulcerative Colitis

RecruitingPhase 1/2Healthy volunteers welcome
  • Xencor Investigative Site, Louisville
Ages 18 to 75 · All sexes · Updated Sep 29, 2026 · NCT06619990

A Randomized Comparison of Stage-Based Care Versus Risk Factor-Based Care for Prevention of Cardiovascular Events

RecruitingHealthy volunteers welcome
  • UofL Health, Louisville
Ages 55 and older · All sexes · Updated Sep 28, 2026 · NCT06112418

Pragmatic Evaluation of Events And Benefits of Lipid-lowering in Older Adults

RecruitingPhase 4Healthy volunteers welcome
  • Louisville VA Medical Center, Louisville
Ages 75 and older · All sexes · Updated Sep 1, 2026 · NCT04262206

Modified P200TE Data Collection

RecruitingObservational studyHealthy volunteers welcome
  • Bennett & Bloom Eye Centers, Louisville
Ages 22 and older · All sexes · Updated Sep 1, 2026 · NCT07796230

Study of GS-4321 in Healthy Participants and Participants With Chronic Hepatitis Delta Virus

RecruitingPhase 1/2Healthy volunteers welcome
  • University of Louisville, Clinical Trials Unit, Louisville
Ages 18 to 69 · All sexes · Updated Aug 27, 2026 · NCT07096193

A Study to Learn About the Treatment LTP001 in Healthy Participants (Part A) and in Participants With PAH (Part B)

RecruitingPhase 1/2Healthy volunteers welcome
  • Norton Infectious Diseases Specialists, Louisville
Ages 18 to 100 · All sexes · Updated Jul 21, 2026 · NCT06649110

Motiva Implants® Post-Approval Study

RecruitingHealthy volunteers welcome
  • CaloAesthetics® Plastic Surgery Center, Louisville
Ages 22 and older · Women · Updated Jul 17, 2026 · NCT06938399

Kentucky - Quality Improvement Implementation Lung Cancer Screening (QUILS™) Health Services Research Intervention

RecruitingHealthy volunteers welcome
  • The James Graham Brown Cancer Center at University of Louisville, Louisville
Ages 18 to 100 · All sexes · Updated Jul 6, 2026 · NCT07682610

Genetic and Environmental Risk Factors for Hemorrhagic Stroke

RecruitingObservational studyHealthy volunteers welcome
  • Baptist Health Louisville, Louisville
Ages 18 and older · All sexes · Updated Jul 2, 2026 · NCT00682695

EXoPERT EMERALD Clinical Study

RecruitingObservational studyHealthy volunteers welcome
  • KCTL, Louisville
Ages 45 and older · All sexes · Updated Jul 1, 2026 · NCT07186296

BoxX-NoAF Clinical Trial

RecruitingHealthy volunteers welcome
  • Norton Healthcare, Louisville
Ages 65 and older · All sexes · Updated Jun 29, 2026 · NCT06989775

Aptis PRUJ Prosthesis for the Treatment of Patients With Proximal Radial Ulna Joint Disorders.

RecruitingHealthy volunteers welcome
  • Kleinert Kutz Hand Care Center, Louisville
Ages 18 to 85 · All sexes · Updated Jun 12, 2026 · NCT05796908

A Study on the Immune Response and Safety of an Investigational Chickenpox Vaccine When Given to Healthy Children 12 to 15 Months of Age

RecruitingPhase 3Healthy volunteers welcome
  • GSK Investigational Site, Louisville
12 Months – 15 Months · All sexes · Updated May 29, 2026 · NCT06740630

Intermediate Visual Space Perception

RecruitingHealthy volunteers welcome
  • University of Louisville, Louisville
Ages 18 to 40 · All sexes · Updated May 7, 2026 · NCT05419713

Ventral or Inguinal Hernia, Robotically Repaired With OviTex Mesh

RecruitingHealthy volunteers welcome
  • University of Louisville, Louisville
Ages 21 and older · All sexes · Updated May 5, 2026 · NCT04779918

Esophageal and Gastric Registry and Biorepository

RecruitingObservational studyHealthy volunteers welcome
  • Norton Healthcare, Louisville
Ages 18 to 85 · All sexes · Updated May 4, 2026 · NCT05180253

Betadine vs Sterile Water for Periurethral Preparation

RecruitingPhase 4Healthy volunteers welcome
  • UofL Physicians - Urogynecology Springs Urogynecology Office, Louisville
  • UofL Health - Urogynecology Mary & Elizabeth Hospital, Medical Plaza 3, Louisville
Ages 18 and older · Women · Updated May 4, 2026 · NCT07044726

Pyloric Sphincter Abnormalities in Patients With Gastroparesis Symptoms

RecruitingObservational studyHealthy volunteers welcome
  • University of Louisville, Louisville
Ages 18 to 85 · All sexes · Updated Apr 3, 2026 · NCT04661215

Health, Environment and Action in Louisville (HEAL) Green Heart Louisville Project

RecruitingHealthy volunteers welcome
  • University of Louisville, Louisville
Ages 30 to 70 · All sexes · Updated Feb 10, 2026 · NCT03670524

Beat Childhood Cancer Specimen Banking and Data Registry

RecruitingObservational studyHealthy volunteers welcome
  • Norton Children's Research Institute/Affiliated with University of Louisville School of Medicine, Louisville
All ages · All sexes · Updated Feb 3, 2026 · NCT04715178

cfDNA Assay Prospective Observational Validation for Early Cancer Detection and Minimal Residual Disease

RecruitingObservational studyHealthy volunteers welcome
  • Baptist Floyd, New Albany · 4 mi away
Ages 40 and older · All sexes · Updated Jan 20, 2026 · NCT05366881

Acute Partial Thickness Burn Study Comparing Transforming Powder Dressing to Standard of Care Dressing

RecruitingPhase 4Healthy volunteers welcome
  • University of Louisville Health, Louisville
Ages 18 to 65 · All sexes · Updated Nov 19, 2025 · NCT05424354

Reactions to Distress (RED) In Louisville, KY Study

RecruitingHealthy volunteers welcome
  • Davidson Hall, Louisville
Ages 18 and older · All sexes · Updated Jun 12, 2025 · NCT07016945

Study Roles of Heavy Metals and Essential Metal Dyshomeostasis in Pulmonary Arterial Hypertension Patients

RecruitingObservational studyHealthy volunteers welcome
  • University of Louisville Health, Louisville
Ages 18 and older · All sexes · Updated May 30, 2025 · NCT04756076

Supporting Resilience Among Re-entered Seniors

RecruitingHealthy volunteers welcome
  • New Legacy Reentry, Louisville
Ages 45 and older · Men · Updated Mar 26, 2025 · NCT06276452

Transvaginal Versus Fluoroscopy-guided Trans Gluteal Pudendal Nerve Block for Pudendal Neuralgia

RecruitingPhase 4Healthy volunteers welcome
  • University of Louisville Division of Urogynecology and Reconstructive Pelvic Surgery, Louisville
Ages 18 and older · Women · Updated Dec 18, 2024 · NCT06644261

Alcohol Misuse, Gut Microbial Dysbiosis and PrEP Care Continuum: Application and Efficacy of SBIRT Intervention

RecruitingHealthy volunteers welcome
  • University of Louisville, Louisville
Ages 18 to 85 · All sexes · Updated Jul 22, 2024 · NCT06005298

Enroll -HD: A Prospective Registry Study in a Global Huntington's Disease Cohort

RecruitingObservational studyHealthy volunteers welcome
  • University of Louisville, Louisville
Ages 18 and older · All sexes · Updated Feb 28, 2024 · NCT01574053

Peppermint Oil for the Treatment of Interstitial Cystitis / Bladder Pain Syndrome

RecruitingPhase 1/2Healthy volunteers welcome
  • Springs Medical Center, Louisville
Ages 18 to 65 · Women · Updated Aug 22, 2022 · NCT04845217

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.