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Head and Neck Cancer clinical trials in New York City, NY

21 studies for Head and Neck Cancer are looking for participants at sites in and around New York City (within about 30 miles). Open a study to see who can join and how to contact the study team.

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The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)

RecruitingPhase 1/2
  • Columbia University Medical Center, New York
  • Memorial Sloan Kettering, New York
Ages 12 and older · All sexes · Updated Oct 2, 2026 · NCT04585750

FORTIFI-HN01: A Study of Ficerafusp Alfa (BCA101) or Placebo in Combination With Pembrolizumab in First-Line PD-L1-pos, R or M HNSCC

RecruitingPhase 2/3
  • Site #0155, New York
  • Site#0142, New York
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT06788990

A Study of HER3-DXd in Subjects With Locally Advanced or Metastatic Solid Tumors

RecruitingPhase 2
  • Memorial Sloan Kettering Hospital, New York
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT06172478

A Study of [225Ac]Ac-AKY-1189 in Patients With Solid Tumors

RecruitingPhase 1
  • Icahn School of Medicine at Mt. Sinai, New York
  • Memorial Sloan Kettering Cancer Center, New York
Ages 18 and older · All sexes · Updated Sep 17, 2026 · NCT07020117

First in Human Study of TUB-030 in Patients With Advanced Solid Tumors

RecruitingPhase 1/2
  • Mount Sinai, New York
Ages 18 and older · All sexes · Updated Sep 11, 2026 · NCT06657222

A Study of Decreasing Radiation Therapy and Chemotherapy in People With Head and Neck Cancer

RecruitingPhase 2
  • Memorial Sloan Kettering Cancer Center (All Protocol Activities), New York
Ages 18 and older · All sexes · Updated Aug 12, 2026 · NCT05544136

Reflectance Confocal Microscopy of Oral Cancers in Vivo: a Preliminary Trial Comparing Intra-oral Imaging With Pathology

RecruitingObservational study
  • Memorial Sloan Kettering Cancer Center, New York
Ages 18 and older · All sexes · Updated Aug 4, 2026 · NCT02507141

A Study of Cemiplimab With Chemotherapy and Immunotherapy in People With Head and Neck Cancer

RecruitingPhase 1
  • Memorial Sloan Kettering Cancer Center, New York
Ages 18 and older · All sexes · Updated Jul 21, 2026 · NCT04722523

A Study of a New PET Scanner in People With Cancer

RecruitingObservational study
  • Memorial Sloan Kettering Cancer Center, New York
Ages 18 and older · All sexes · Updated Jul 8, 2026 · NCT07690917

First-in-Human Study of Tersolisib (STX-478) as Monotherapy and in Combination With Other Antineoplastic Agents in Participants With Advanced Solid Tumors

RecruitingPhase 1/2
  • Memorial Sloan Kettering Cancer Center, New York
Ages 18 and older · All sexes · Updated Jul 7, 2026 · NCT05768139

Implementing the NYU Electronic Patient Visit Assessment (ePVA) for Head and Neck Cancer In Rural and Urban Populations

Recruiting
  • NYU Meyers College of Nursing, New York
  • NYU Langone Perlmutter Cancer Center, New York
Ages 18 and older · All sexes · Updated Jul 6, 2026 · NCT06030011

A Study of Neurocognitive Tests and Questionnaires for People With Head and Neck Cancer Who Are Undergoing Radiation Therapy

RecruitingObservational study
  • Memorial Sloan Kettering Cancer Center (All Protocol Activities), New York
Ages 18 to 89 · All sexes · Updated Jun 5, 2026 · NCT05207098

Brodalumab in the Treatment of Immune-Related Adverse Events

RecruitingPhase 1
  • Columbia University Irving Medical Center, New York
Ages 18 and older · All sexes · Updated May 13, 2026 · NCT06673329

New MRI Biomarkers in Head and Neck Cancers

RecruitingObservational study
  • Memorial Sloan Kettering Cancer Center, New York
Ages 18 and older · All sexes · Updated Apr 14, 2026 · NCT03483337

Prospective Evaluation of Pencil Beam Scanning Proton Therapy for Previously Irradiated Tumors

Recruiting
  • The New York Proton Center, New York
Ages 18 and older · All sexes · Updated Apr 13, 2026 · NCT05313191

Impact of Photobiomodulation (PBM) on Biomarkers of Radiation Lymphedema and Fibrosis in Head and Neck Cancer Patients

Recruiting
  • NYU Langone Health, New York
Ages 18 and older · All sexes · Updated Mar 30, 2026 · NCT06708754

Stereotactic MRI-guided Focused Ultrasound Mesencephalotomy

Recruiting
  • Weill Cornell Medicine, New York
Ages 18 to 85 · All sexes · Updated Feb 12, 2026 · NCT07405645

VMD-928 Monotherapy and in Combination With Pembrolizumab to Treat TrkA Overexpression Driven Solid Tumors or Lymphoma

RecruitingPhase 1/2
  • Weill Cornell Medicine, Cornell University (site 126), New York
Ages 18 to 80 · All sexes · Updated Dec 11, 2025 · NCT03556228

SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

RecruitingObservational study
  • Massive Bio SYNERGY-AI site, New York
All ages · All sexes · Updated Oct 28, 2025 · NCT03452774

Study of Safety and Tolerability of BCA101 Monotherapy and in Combination Therapy in Patients With EGFR-driven Advanced Solid Tumors

RecruitingPhase 1
  • Memorial Sloan Kettering, New York
  • Columbia University Herbert Irving Comprehensive Cancer Center, New York
Ages 18 and older · All sexes · Updated Aug 15, 2025 · NCT04429542

Comprehensive Outcomes for After Cancer Health

RecruitingHealthy volunteers welcome
  • Memorial Sloan Kettering Cancer Center, New York
Ages 18 and older · All sexes · Updated Dec 11, 2024 · NCT05349227

About Head and Neck Cancer

Head and neck cancer includes cancers of the mouth, nose, sinuses, salivary glands, throat, and lymph nodes. Read the different symptoms of each type.

More about Head and Neck Cancer on MedlinePlus

Head and Neck Cancer trials in other cities

Other studies in New York City

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.