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Metastatic Cancer clinical trials in Tampa, FL

29 studies for Metastatic Cancer are looking for participants at sites in and around Tampa (within about 30 miles). Open a study to see who can join and how to contact the study team.

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BEACON-1: Study of AVZO-103 as a Single Agent and in Combination Therapy in Patients With Locally Advanced or Metastatic Urothelial Cancer or Other Solid Tumors (AVZO-103-1001)

RecruitingPhase 1/2
  • Avenzo Therapeutics Recruiting Site, Tampa
Ages 18 and older · All sexes · Updated Oct 5, 2026 · NCT07193511

Open-Label Study of BBO-10203 in Subjects With Advanced Solid Tumors

RecruitingPhase 1
  • Moffitt Cancer Center, Tampa
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT06625775

A First in Human Study of ALX2004 With Advanced or Metastatic Selected Solid Tumors

RecruitingPhase 1
  • ALX Center 7, Tampa
Ages 18 and older · All sexes · Updated Sep 30, 2026 · NCT07085091

Zanzalintinib Versus Everolimus in Participants With Locally Advanced or Metastatic Neuroendocrine Tumors

RecruitingPhase 2/3
  • Moffitt Cancer Center, Tampa
Ages 18 and older · All sexes · Updated Sep 29, 2026 · NCT06943755

A Study of IDE892 as Monotherapy and Combination in MTAP-deleted Advanced Solid Tumors

RecruitingPhase 1
  • Moffitt Cancer Center, Tampa
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07277413

ASPEN-09-03: A Study of Evorpacept in Combination With Trastuzumab and Chemotherapy in Metastatic HER2-Positive Breast Cancer

RecruitingPhase 2
  • Moffitt Cancer Center, Tampa
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT07007559

A Study of LY4257496 in Participants With Cancer (OMNIRAY)

RecruitingPhase 1
  • Moffitt, Tampa
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07114601

A Three-Part Phase 3 Study of Sofetabart Mipitecan in Participants With Platinum-Resistant (Part A) and Platinum-Sensitive (Parts B and C) Ovarian Cancer

RecruitingPhase 3
  • Moffitt Cancer Center, Tampa
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07213804

A Study of Tersolisib (LY4064809/STX-478) With Other Anti-Cancer Treatments in Participants With Advanced Breast Cancer With a Genetic Change (PIK3CA)

RecruitingPhase 3
  • Moffitt Cancer Center, Richard M. Shulze Family Foundation Outpatient Center, Tampa
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07174336

Study of Elironrasib and Daraxonrasib as Monotherapies and Combination Therapy in Participants With Advanced KRAS G12C Mutant Solid Tumors

RecruitingPhase 1/2
  • Moffitt Cancer Center and Research Institute, Tampa
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT06128551

A First-in-Human Trial of BLU-924 (SAR449336) in Advanced Solid Tumors Harboring KRAS Mutations

RecruitingPhase 1/2
  • Moffitt Cancer Center, Tampa
Ages 18 and older · All sexes · Updated Sep 21, 2026 · NCT07629960

AVENTINE-1: Study of AVZO-1418 as a Single Agent and in Combination Therapy in Patients With Locally Advanced or Metastatic Solid Tumors (AVZO-1418-1001)

RecruitingPhase 1/2
  • Avenzo Therapeutics Recruiting Site, Tampa
Ages 18 to 75 · All sexes · Updated Sep 4, 2026 · NCT07038343

A Study of ERAS-0015 in Patients With Advanced or Metastatic Solid Tumors

RecruitingPhase 1
  • Moffitt Cancer Center, Tampa
Ages 18 to 99 · All sexes · Updated Sep 1, 2026 · NCT06983743

Puxitatug Samrotecan (AZD8205) Monotherapy vs Chemotherapy in B7-H4-selected Endometrial Cancer (Bluestar-Endometrial01)

RecruitingPhase 3
  • Research Site, Tampa
Ages 18 and older · Women · Updated Jul 29, 2026 · NCT07044336

Study of Orally Administered MOMA-341 in Participants With Advanced or Metastatic Solid Tumors

RecruitingPhase 1
  • Investigative Site #128, Tampa
Ages 18 and older · All sexes · Updated Jul 23, 2026 · NCT06974110

A Phase 1 Dose-escalation Trial of KST-6051 in Participants With Advanced Solid Tumors With Kirsten Rat Sarcoma Viral Oncogene Homolog (KRAS) Mutation

RecruitingPhase 1
  • Moffitt Cancer Center, Tampa
Ages 18 and older · All sexes · Updated Jun 29, 2026 · NCT07458347

LUNAR-2: TTFields With Pembrolizumab + Platinum-based Chemotherapy for Metastatic NSCLC

RecruitingPhase 3
  • Moffitt Cancer Center, Tampa
Ages 18 and older · All sexes · Updated Jun 25, 2026 · NCT06216301

A Study of XB628 Alone and in Combination With Zanzalintinib in Participants With Recurrent Advanced or Metastatic Solid Tumors

RecruitingPhase 1
  • Exelixis Clinical Site #8, Tampa
Ages 18 and older · All sexes · Updated Jun 24, 2026 · NCT06952010

(Peak) A Phase 3 Randomized Trial of CGT9486+Sunitinib vs. Sunitinib in Subjects With Gastrointestinal Stromal Tumors

RecruitingPhase 3
  • Moffitt Cancer Center, Tampa
Ages 18 and older · All sexes · Updated Jun 16, 2026 · NCT05208047

Abiraterone, Enzalutamide, or Apalutamide in Castrate-sensitive Prostate Cancer.

RecruitingPhase 2
  • James A. Haley Veterans Administration Hospital, Tampa
Ages 18 and older · Men · Updated Jun 15, 2026 · NCT05422911

MEM-288 Oncolytic Virus Alone and in Combination With Standard of Care Therapy in Advanced Solid Tumors

RecruitingPhase 1
  • Moffitt Cancer Center, Tampa
Ages 18 and older · All sexes · Updated Jun 11, 2026 · NCT05076760

Study of RMC-9805 in Participants With KRAS G12D-Mutant Solid Tumors

RecruitingPhase 1
  • Lee Moffitt Cancer Center, Tampa
Ages 18 and older · All sexes · Updated Jun 3, 2026 · NCT06040541

BBO-11818 in Adult Subjects With KRAS Mutant Cancer

RecruitingPhase 1
  • Moffitt Cancer Center, Tampa
Ages 18 and older · All sexes · Updated Jun 2, 2026 · NCT06917079

Study of RMC-6236 in Patients With Advanced Solid Tumors Harboring Specific Mutations in RAS

RecruitingPhase 1/2
  • Moffitt Cancer Center, Tampa
Ages 18 and older · All sexes · Updated May 15, 2026 · NCT05379985

Placebo-Controlled Trial of IFx-Hu2.0 Followed By Pembrolizumab In Checkpoint Inhibitor Naïve Participants With Advanced Or Metastatic Merkel Cell Carcinoma

RecruitingPhase 2/3
  • Moffitt Cancer Center, Tampa
Ages 18 and older · All sexes · Updated Apr 17, 2026 · NCT06947928

A Study of Ficlatuzumab in Combination With Cetuximab in Participants With Recurrent or Metastatic (R/M) HPV Negative Head and Neck Squamous Cell Carcinoma

RecruitingPhase 3
  • Moffitt Cancer Center, Tampa
Ages 18 and older · All sexes · Updated Apr 9, 2026 · NCT06064877

SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

RecruitingObservational study
  • Massive Bio SYNERGY-AI site, Tampa
All ages · All sexes · Updated Oct 28, 2025 · NCT03452774

IFx-Hu2.0 As An Adjunctive Therapy To Pembrolizumab In Advanced Or Metastatic Merkel Cell Carcinoma (MCC)

RecruitingPhase 1
  • H. Lee Moffitt Cancer Center and Research Institute, Tampa
Ages 18 and older · All sexes · Updated Oct 15, 2025 · NCT06940440

Metastatic Cancer trials in other cities

Other studies in Tampa

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.