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Metastatic Cancer clinical trials in Indianapolis, IN

19 studies for Metastatic Cancer are looking for participants at sites in and around Indianapolis (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

A Study of LY4052031 in Participants With Advanced or Metastatic Urothelial Cancer or Other Solid Tumors

RecruitingPhase 1
  • IU Simon Cancer Center, Indianapolis
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT06465069

Open-Label Study of BBO-10203 in Subjects With Advanced Solid Tumors

RecruitingPhase 1
  • Indiana University Simon Comprehensive Cancer Center, Indianapolis
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT06625775

Symbiotic-GI-03: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Metastatic Colorectal Cancer

RecruitingPhase 3
  • Franciscan Health, Indianapolis
  • Franciscan Health Mooresville, Mooresville · 16 mi away
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07222800

Symbiotic-Lung-01 : A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Locally Advanced or Metastatic Non-Small Cell Lung Cancer

RecruitingPhase 3
  • Community Health Network, Inc, Indianapolis
  • Community Health Network, Inc., Indianapolis
  • Community Health Network, Inc., Indianapolis
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT07222566

A Three-Part Phase 3 Study of Sofetabart Mipitecan in Participants With Platinum-Resistant (Part A) and Platinum-Sensitive (Parts B and C) Ovarian Cancer

RecruitingPhase 3
  • Indiana University Melvin and Bren Simon Cancer Center, Indianapolis
  • Franciscan Health, Indianapolis
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07213804

A Study of Vepugratinib (LY3866288) in Participants With Cancer in the Urinary Tract

RecruitingPhase 3
  • Indiana University Melvin and Bren Simon Cancer Center, Indianapolis
  • Franciscan Health, Indianapolis
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07218380

A Study of Tersolisib (LY4064809/STX-478) With Other Anti-Cancer Treatments in Participants With Advanced Breast Cancer With a Genetic Change (PIK3CA)

RecruitingPhase 3
  • Indiana University Health University Hospital, Indianapolis
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07174336

Study of Elironrasib and Daraxonrasib as Monotherapies and Combination Therapy in Participants With Advanced KRAS G12C Mutant Solid Tumors

RecruitingPhase 1/2
  • Community Health Network, Indianapolis
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT06128551

AMG 436 as Monotherapy and Combination Therapy in Participants With MSI-H/dMMR Solid Tumors

RecruitingPhase 1
  • Community Health Network MD Anderson Cancer Center - North, Indianapolis
Ages 18 to 99 · All sexes · Updated Sep 21, 2026 · NCT07403721

Prospective Validation of a Points Score System Predicting 30-day Survival

RecruitingObservational study
  • Methodist Hospital, Indianapolis
  • IU Health West, Avon · 13 mi away
Ages 18 and older · All sexes · Updated Sep 17, 2026 · NCT05100342

A Study of First-Line Olomorasib (LY3537982) and Pembrolizumab With or Without Chemotherapy in Patients With Advanced KRAS G12C-Mutant Non-small Cell Lung Cancer

RecruitingPhase 3
  • Indiana University Melvin and Bren Simon Cancer Center, Indianapolis
  • Franciscan Health, Indianapolis
  • Community Cancer Center North, Indianapolis
Ages 18 and older · All sexes · Updated Sep 8, 2026 · NCT06119581

A Study of IDP-001 in Advanced or Metastatic Solid Tumors

RecruitingPhase 1/2
  • Community Cancer Center North, Indianapolis
Ages 18 and older · All sexes · Updated Sep 3, 2026 · NCT07602842

FORAGER-1: A Study of Vepugratinib (LY3866288; LOXO-435) in Participants With Cancer With a Change in a Gene Called FGFR3

RecruitingPhase 1
  • Indiana University (IU) Melvin and Bren Simon Cancer Center, Indianapolis
Ages 18 and older · All sexes · Updated Aug 20, 2026 · NCT05614739

A Study of ART0380 for the Treatment of Advanced or Metastatic Solid Tumors

RecruitingPhase 1/2
  • Community Health Network, Indianapolis
Ages 18 and older · All sexes · Updated Jul 30, 2026 · NCT04657068

Puxitatug Samrotecan (AZD8205) Monotherapy vs Chemotherapy in B7-H4-selected Endometrial Cancer (Bluestar-Endometrial01)

RecruitingPhase 3
  • Research Site, Indianapolis
Ages 18 and older · Women · Updated Jul 29, 2026 · NCT07044336

LUNAR-2: TTFields With Pembrolizumab + Platinum-based Chemotherapy for Metastatic NSCLC

RecruitingPhase 3
  • Franciscan Health Indianapolis, Indianapolis
Ages 18 and older · All sexes · Updated Jun 25, 2026 · NCT06216301

A Study of LY4175408 in Participants With Advanced Cancer

RecruitingPhase 1
  • Community Health Network, Indianapolis
Ages 18 and older · All sexes · Updated Jun 23, 2026 · NCT07046923

Evaluating Disparities in Precision Oncology

RecruitingObservational study
  • Indiana University Health Melvin and Bren Simon Comprehensive Cancer Center, Indianapolis
Ages 18 and older · All sexes · Updated Jun 16, 2026 · NCT06081517

Veterans Affairs Seamless Phase II/III Randomized Trial of STAndard Systemic theRapy With or Without PET-directed Local Therapy for Oligometastatic pRosTate Cancer

RecruitingPhase 2/3
  • Richard L. Roudebush VA Medical Center, Indianapolis, IN, Indianapolis
Ages 18 and older · Men · Updated Apr 8, 2026 · NCT04787744

Metastatic Cancer trials in other cities

Other studies in Indianapolis

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.