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Breast Cancer clinical trials in Ann Arbor, MI

27 studies for Breast Cancer are looking for participants at sites in and around Ann Arbor (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

Phase 3 Study of RLY-2608 + Fulvestrant vs Capivasertib + Fulvestrant as Treatment for Locally Advanced or Metastatic PIK3CA-mutant HR+/HER2- Breast Cancer

RecruitingPhase 3
  • University of Michigan, Ann Arbor
Ages 18 and older · All sexes · Updated Oct 5, 2026 · NCT06982521

A Study of PHST001 in Advanced Solid Tumors

RecruitingPhase 1
  • University of Michigan Rogel Cancer Center, Ann Arbor
Ages 18 and older · All sexes · Updated Oct 5, 2026 · NCT06840886

Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection

RecruitingObservational studyHealthy volunteers welcome
  • Trinity Health Saint Joseph Mercy Hospital Ann Arbor, Ann Arbor
  • Huron Gastroenterology PC, Ypsilanti · 7 mi away
  • Trinity Health IHA Medical Group Hematology Oncology Ann Arbor Campus, Ypsilanti · 7 mi away
  • and 4 more
Ages 40 to 75 · All sexes · Updated Oct 2, 2026 · NCT05334069

ASPEN-09-03: A Study of Evorpacept in Combination With Trastuzumab and Chemotherapy in Metastatic HER2-Positive Breast Cancer

RecruitingPhase 2
  • University of Michigan Rogel Cancer Center, Ann Arbor
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT07007559

Palazestrant in Combination With Ribociclib for the First-line Treatment of ER+/HER2- Advanced Breast Cancer

RecruitingPhase 3
  • Clinical Trial Site, Ann Arbor
Ages 18 and older · All sexes · Updated Sep 23, 2026 · NCT07085767

A Phase 1/1b Study of IAM1363 in HER2 Cancers

RecruitingPhase 1
  • University of Michigan, Ann Arbor
Ages 18 and older · All sexes · Updated Sep 9, 2026 · NCT06253871

Testing Laser Therapy for Treatment of Vaginal Dryness in Survivors of Breast Cancer, The Revitalize Trial

RecruitingPhase 3
  • Trinity Health IHA - Obstetrics and Gynecology West Arbor, Ann Arbor
Ages 22 and older · Women · Updated Sep 3, 2026 · NCT05379153

Evaluating Minimal Residual Disease (MRD) Through Longitudinal Circulating Tumor DNA (ctDNA) Profiling in Breast Malignancies

RecruitingObservational study
  • Trinity Health, Ann Arbor
Ages 18 to 99 · All sexes · Updated Sep 3, 2026 · NCT07211178

Evaluating the Addition of Adjuvant Chemotherapy to Ovarian Function Suppression Plus Endocrine Therapy in Premenopausal Patients With pN0-1, ER-Positive/HER2-Negative Breast Cancer and an Oncotype Recurrence Score Less Than or Equal to 25

RecruitingPhase 3
  • Trinity Health Saint Joseph Mercy Hospital Ann Arbor, Ann Arbor
  • University of Michigan Rogel Cancer Center, Ann Arbor
  • Huron Gastroenterology PC, Ypsilanti · 7 mi away
  • and 6 more
Ages 18 to 60 · Women · Updated Sep 2, 2026 · NCT05879926

E-Mindfulness Approaches for Living After Breast Cancer

RecruitingPhase 3
  • Trinity Health Saint Joseph Mercy Hospital Ann Arbor, Ann Arbor
Ages 18 to 50 · All sexes · Updated Aug 4, 2026 · NCT06748222

Low Dose Tamoxifen With or Without Omega-3 Fatty Acids for Breast Cancer Risk Reduction

RecruitingPhase 2Healthy volunteers welcome
  • University of Michigan Rogel Cancer Center, Ann Arbor
Ages 45 to 74 · Women · Updated Aug 4, 2026 · NCT06195306

Finding the Best Tamoxifen Dose for Breast Cancer Risk Reduction in Premenopausal Women, RENAISSANCE Trial

RecruitingPhase 2
  • University of Michigan Rogel Cancer Center, Ann Arbor
Ages 18 to 55 · Women · Updated Jul 27, 2026 · NCT06184750

Study of Ribociclib Administered Concurrently With Postoperative Radiation Therapy in Patients With High-Risk, HR+/HER2- Breast Cancer

RecruitingPhase 1
  • University of Michigan, Ann Arbor
Ages 18 and older · Women · Updated Jul 15, 2026 · NCT05996107

Pharmacokinetic Study of Skeletal Muscle Area-based Paclitaxel Infusion in Patients With Cancer

RecruitingPhase 4
  • University of Michigan Rogel Cancer Center, Ann Arbor
Ages 18 and older · Women · Updated Jul 2, 2026 · NCT05183126

Leuprolide and Goserelin for Ovarian Function Suppression in Pre- or Peri-menopausal Women With Breast Cancer, OFS Trial

RecruitingPhase 2
  • University of Michigan Comprehensive Cancer Center, Ann Arbor
Ages 18 and older · Women · Updated Jun 23, 2026 · NCT07158021

De-Escalation of Breast Radiation Trial for Hormone Sensitive, HER-2 Negative, Oncotype Recurrence Score Less Than or Equal to 18 Breast Cancer (DEBRA)

RecruitingPhase 3
  • Trinity Health Saint Joseph Mercy Hospital Ann Arbor, Ann Arbor
  • University of Michigan Rogel Cancer Center, Ann Arbor
  • Trinity Health IHA Medical Group Hematology Oncology Ann Arbor Campus, Ypsilanti · 7 mi away
  • and 5 more
Ages 50 to 70 · All sexes · Updated Apr 23, 2026 · NCT04852887

Evexomostat Plus PI3K or AKT Inhibitor and Fulvestrant in Patients With a PI3K Alteration and HR+/Her2- Breast Cancer

RecruitingPhase 1/2
  • Trinity Health, Ypsilanti · 7 mi away
Ages 18 and older · All sexes · Updated Apr 22, 2026 · NCT05455619

CIPN Decision Aid for the Improvement of Chemotherapy Decision Making in Patients With Breast Cancer

Recruiting
  • University of Michigan Comprehensive Cancer Center, Ann Arbor
All ages · All sexes · Updated Apr 8, 2026 · NCT06915168

Assessing Benefits and Harms of Cannabis/Cannabinoid Use Among Cancer Patients Treated in Community Oncology Clinics

RecruitingObservational study
  • Trinity Health Saint Joseph Mercy Hospital Ann Arbor, Ann Arbor
Ages 18 and older · All sexes · Updated Mar 17, 2026 · NCT06418204

A Self-Monitoring Platform for Tracking Medication Safety and Concerns in Cancer Patients

Recruiting
  • University of Michigan Comprehensive Cancer Center, Ann Arbor
Ages 18 and older · All sexes · Updated Jan 21, 2026 · NCT07291414

SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

RecruitingObservational study
  • Massive Bio SYNERGY-AI site, Ann Arbor
All ages · All sexes · Updated Oct 28, 2025 · NCT03452774

The Cancer of the Pancreas Screening-5 CAPS5)Study

RecruitingPhase 3
  • University of Michigan, Ann Arbor
Ages 18 and older · All sexes · Updated Oct 9, 2025 · NCT02000089

S1501 Dual Observational and Randomized Cohort Study of Patients With Metastatic HER-2+ Breast Cancer at Risk of Cardiac Toxicity

RecruitingPhase 3
  • Saint Joseph Mercy Hospital, Ann Arbor
  • University of Michigan Comprehensive Cancer Center, Ann Arbor
  • Trinity Health IHA Medical Group Hematology Oncology Ann Arbor Campus, Ypsilanti · 7 mi away
Ages 18 and older · All sexes · Updated Oct 8, 2025 · NCT03418961

A Study to Evaluate TROP2 ADC LCB84 Single Agent and in Combination With an Anti-PD-1 Ab in Advanced Solid Tumors

RecruitingPhase 1/2
  • University of Michigan, Ann Arbor
Ages 18 and older · All sexes · Updated Sep 24, 2025 · NCT05941507

CtDNA Based MRD Testing for NAC Monitoring in TNBC

RecruitingObservational study
  • Trinity Health-Michigan, Ypsilanti · 7 mi away
Ages 18 and older · Women · Updated Jan 7, 2025 · NCT06230185

About Breast Cancer

Breast cancer is a cancer that starts in the breast tissue, when cells change and grow out of control. These extra cells can form a mass called a tumor.

More about Breast Cancer on MedlinePlus

Breast Cancer trials in other cities

Other studies in Ann Arbor

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.