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Cardiovascular Disease clinical trials in New York City, NY

33 studies for Cardiovascular Disease are looking for participants at sites in and around New York City (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

EASi-PROTKT™ - A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease

RecruitingPhase 3
  • NYC Research Inc., New York
  • New York Cardiovascular Specialist PC, New York
Ages 18 and older · All sexes · Updated Sep 30, 2026 · NCT07064473

A Prospective, Multicenter, Randomized Controlled Trial to Investigate the Value of Coronary CT Angiography in the Understanding and Management of Coronary Calcium (The Optimal Trial)

Recruiting
  • Columbia University Irving Medical Center/NewYork-Presbyterian Hospital, New York
  • Weill Medical College of Cornell University, New York
Ages 18 to 85 · All sexes · Updated Sep 28, 2026 · NCT07286578

Capitalizing on AI to CapTure Undiagnosed Structural Heart Disease

Recruiting
  • Columbia University Irving Medical Center / NewYork-Presbyterian, New York
Ages 40 and older · All sexes · Updated Sep 25, 2026 · NCT07843004

Product Surveillance Registry

RecruitingObservational study
  • New York, New York
All ages · All sexes · Updated Sep 18, 2026 · NCT01524276

Zenith® Fenestrated+ Clinical Study

Recruiting
  • New York University Langone Medical Center, New York
  • Columbia University Irving Medical Center/NY Presbyterian Hospital, New York
Ages 18 and older · All sexes · Updated Sep 17, 2026 · NCT04875429

Transcatheter Mitral Valve Replacement With the Medtronic Intrepid™ TMVR System in Patients With Severe Symptomatic Mitral Regurgitation.

Recruiting
  • NYU Langone Medical Center, New York
  • The Mount Sinai Hospital, New York
  • New York-Presbyterian Hospital Columbia University Medical Center, New York
  • and 1 more
Ages 18 and older · All sexes · Updated Sep 15, 2026 · NCT03242642

Investigation of the BrioVAD System for the Treatment of Left Ventricular Heart Failure

Recruiting
  • NYU Langone Health, New York
  • Mount Sinai, New York
  • Columbia University Irving Medical Center/ New York Presbyterian Hospital, New York
  • and 1 more
Ages 18 to 100 · All sexes · Updated Sep 9, 2026 · NCT06310031

An Open Label Extension (OLE) Study (Following Completion of CTQJ230A12301) to Evaluate Long-term Safety and Tolerability of Pelacarsen (TQJ230)

RecruitingPhase 3
  • Weill Cornell Medical Center, New York
  • Icahn School of Med at Mt Sinai, New York
  • Lenox Hill Hospital, New York
Ages 18 to 100 · All sexes · Updated Sep 4, 2026 · NCT07517263

Safety and Performance Assessment of the Sphere-9™ Catheter and Affera™ Ablation System for the Treatment of Ventricular Tachycardia (Sphere-9 VT EFS)

Recruiting
  • Icahn School of Medicine at Mount Sinai, New York
Ages 18 to 85 · All sexes · Updated Sep 3, 2026 · NCT06703489

Pragmatic Evaluation of Events And Benefits of Lipid-lowering in Older Adults

RecruitingPhase 4Healthy volunteers welcome
  • VA New York Harbor Healthcare System, New York
  • Weill Cornell Medical College, New York
Ages 75 and older · All sexes · Updated Sep 1, 2026 · NCT04262206

Exercise Activity Intervention With Sensor-Based Engagement in Patients With Atrial Fibrillation

Recruiting
  • Icahn School of Medicine at Mount Sinai, New York
Ages 18 and older · All sexes · Updated Aug 24, 2026 · NCT06938412

A Phase III Study of AZD0780 on Major Adverse CV Events in Patients With a History of ASCVD Events or at High Risk for a First Event

RecruitingPhase 3
  • Research Site, New York
  • Research Site, New York
  • Research Site, New York
Ages 18 and older · All sexes · Updated Aug 24, 2026 · NCT07000357

OCEAN(a)-PreEvent - Olpasiran Trials of Cardiovascular Events And LipoproteiN(a) Reduction to Prevent First Major Cardiovascular Events

RecruitingPhase 3
  • Icahn School of Medicine at Mount Sinai, New York
  • Mount Sinai Queens, New York
Ages 50 to 105 · All sexes · Updated Aug 21, 2026 · NCT07136012

Improving the Heart Health of Home Health Aides

RecruitingHealthy volunteers welcome
  • 1199 SEIU Home Care Industry Education Fund, New York
  • Weill Cornell Medicine, New York
Ages 18 and older · All sexes · Updated Aug 20, 2026 · NCT07067398

Global Paradise System US Post Approval Study

RecruitingObservational study
  • NYU Langone Health - Bellevue Hosptial, New York
  • Columbia University Medical Center/New York Presbyterian Hospital, New York
Ages 18 and older · All sexes · Updated Aug 12, 2026 · NCT06297291

The TRICURE EFS Study

Recruiting
  • Columbia University Medical Center/ NewYork Presbyterian Hospital, New York
Ages 18 and older · All sexes · Updated Jul 23, 2026 · NCT06506942

PROACTIVE-HF-2 Trial Heart Failure NYHA Class II and III

Recruiting
  • Mount Sinai West, New York
  • Mount Sinai, New York
  • Lenox Hill/ Northwell Health, New York
Ages 18 and older · All sexes · Updated Jun 29, 2026 · NCT05934487

Trial to Evaluate Safety And Effectiveness of Mechanical Circulatory Support in Patients With Advancing Heart Failure

Recruiting
  • New York-Presbyterian/Columbia University Medical Center, New York
Ages 18 and older · All sexes · Updated Jun 10, 2026 · NCT06526195

Study to Evaluate Efficacy and Safety of Inclisiran in Children With Heterozygous Familial Hypercholesterolemia

RecruitingPhase 3
  • Icahn School of Med at Mt Sinai, New York
Ages 6 to 11 · All sexes · Updated May 15, 2026 · NCT06597019

Pivotal Study for the Cardiac Performance System (CPS)

RecruitingObservational study
  • Columbia University Irving Medical Center / NewYork-Presbyterian Hospital, New York
Ages 18 and older · All sexes · Updated Apr 24, 2026 · NCT06870591

HARP Mindfulness Study

Recruiting
  • NYU Langone Health, New York
Ages 18 and older · All sexes · Updated Apr 17, 2026 · NCT05841784

DELINEATE-Prospective

RecruitingObservational study
  • Columbia University Irving Medical Center, New York
Ages 18 and older · All sexes · Updated Apr 16, 2026 · NCT07197736

The EMPOWER Trial - The Carillon Mitral Contour System® in Treating Heart Failure With FMR

Recruiting
  • Northwell Staten Island, New York
Ages 18 and older · All sexes · Updated Apr 13, 2026 · NCT03142152

A Patient Activation Approach to Implementing Depression Treatment in Cardiac Patients

Recruiting
  • Columbia University Irving Medical Center, New York
Ages 18 and older · All sexes · Updated Mar 6, 2026 · NCT07390331

A Pilot Feasibility and Acceptability Study of Remote ExerciSe Training mOdalities (PRESTO)

Recruiting
  • NYU Langone Health, New York
Ages 45 and older · All sexes · Updated Mar 5, 2026 · NCT06931470

Food and Microbiome Longitudinal Investigation (FAMiLI)

RecruitingObservational studyHealthy volunteers welcome
  • New York University School of Medicine, New York
Ages 40 and older · All sexes · Updated Feb 25, 2026 · NCT03293758

Community Health Workers United to Reduce Colorectal Cancer and Cardiovascular Disease Among People at Higher Risk

RecruitingHealthy volunteers welcome
  • Columbia University Irving Medical Center, New York
Ages 45 and older · All sexes · Updated Sep 16, 2025 · NCT05174286

MagicTouch™Sirolimus-Coated Balloon for Treatment of Coronary Artery Lesions in Small Vessels

Recruiting
  • Icahn School of Medicine at Mount Sinai/ Mount Sinai Hospital, New York
  • Columbia University/NYP, New York
Ages 18 to 80 · All sexes · Updated Sep 11, 2025 · NCT06271590

Pericardiotomy in Cardiac Surgery

Recruiting
  • Weill Cornell Medicine, New York
Ages 18 and older · All sexes · Updated Jul 14, 2025 · NCT06486636

MagicTouch for Treatment of In-Stent Restenosis in Coronary Artery Lesions

Recruiting
  • VA New York Harbor Healthcare System, New York
  • NYU Langone Health, New York
  • Columbia University Medical Center/NYPH, New York
Ages 18 to 110 · All sexes · Updated Feb 25, 2025 · NCT05908331

PARTNER 3 Trial - Aortic Valve-in-Valve

Recruiting
  • Cornell University, New York
  • Columbia University Medical Center/ New York Presbyterian Hospital, New York
All ages · All sexes · Updated May 10, 2024 · NCT03003299

Cardiovascular Disease trials in other cities

Other studies in New York City

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.