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Non-Small Cell Lung Cancer clinical trials in Saint Paul, MN

19 studies for Non-Small Cell Lung Cancer are looking for participants at sites in and around Saint Paul (within about 30 miles). Open a study to see who can join and how to contact the study team.

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Testing the Impact of an Anti-Cancer Drug, Atezolizumab, After Surgery to Prevent Early Stage Non-small Cell Lung Cancer From Returning, AASI-NSCLC Trial

RecruitingPhase 3
  • United Hospital, Saint Paul
Ages 18 and older · All sexes · Updated Oct 5, 2026 · NCT07388524

A Study of HER3-DXd in Subjects With Locally Advanced or Metastatic Solid Tumors

RecruitingPhase 2
  • Health Partners Cancer Center at Regions Hospital, Saint Paul
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT06172478

Immunotherapy After Surgery for People Who Have No Remaining Cancer Cells After Standard Treatment for Early-Stage Non-Small Cell Lung Cancer, INSIGHT Trial

RecruitingPhase 3
  • Regions Hospital, Saint Paul
  • United Hospital, Saint Paul
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT06498635

A Study to Learn About the Study Medicine Called PF-08046054/SGN-PDL1V Versus Docetaxel in Adult Participants With Previously-Treated Programmed Cell Death Ligand 1 (PD-L1) Positive Non-Small-Cell Lung Cancer (NSCLC)

RecruitingPhase 3
  • Allina Health Cancer Institute - United Hospital, Saint Paul
  • Minnesota Oncology Hematology, P.A., Maplewood · 5 mi away
  • Minnesota Oncology Hematology, PA, Woodbury · 7 mi away
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07144280

Symbiotic-Lung-01 : A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Locally Advanced or Metastatic Non-Small Cell Lung Cancer

RecruitingPhase 3
  • Allina Health Cancer Institute - United Hospital, Saint Paul
  • Minnesota Oncology Hematology, P.A., Maplewood · 5 mi away
  • Minnesota Oncology Hematology, P.A., Woodbury · 7 mi away
  • and 1 more
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT07222566

This is a Study to Learn About How the Combination of the Study Medicines Sigvotatug Vedotin Plus Pembrolizumab Works in People With Non-small Cell Lung Cancer With High Levels of PD-L1.

RecruitingPhase 3
  • Regions Hospital, Saint Paul
  • M Health Fairview St. John's Hospital, Maplewood · 5 mi away
  • Minnesota Oncology Hematology PA, Maplewood · 5 mi away
  • and 1 more
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06758401

Testing Osimertinib as a Treatment for Lung Cancers With an EGFR Exon 20 Change

RecruitingPhase 2
  • Regions Hospital, Saint Paul
  • United Hospital, Saint Paul
  • Minnesota Oncology Hematology PA-Maplewood, Maplewood · 5 mi away
  • and 3 more
Ages 18 and older · All sexes · Updated Sep 24, 2026 · NCT03191149

Clinical Study of Ivonescimab for First-line Treatment of Metastatic NSCLC Patients With High PD-L1

RecruitingPhase 3
  • Clinical Study Site, Saint Paul
Ages 18 and older · All sexes · Updated Sep 18, 2026 · NCT06767514

A Study of First-Line Olomorasib (LY3537982) and Pembrolizumab With or Without Chemotherapy in Patients With Advanced KRAS G12C-Mutant Non-small Cell Lung Cancer

RecruitingPhase 3
  • HealthPartners Cancer Research Center, Saint Paul
Ages 18 and older · All sexes · Updated Sep 8, 2026 · NCT06119581

Phase III, Open-label Study of First-line Osimertinib With or Without Datopotamab Deruxtecan for EGFRm Locally Advanced or Metastatic Non-small Cell Lung Cancer

RecruitingPhase 3
  • Research Site, Saint Paul
Ages 18 and older · All sexes · Updated Aug 26, 2026 · NCT06350097

Rinatabart Sesutecan (Rina-S, PRO1184, GEN1184) for Advanced Solid Tumors (GCT1184-01/ PRO1184-001)

RecruitingPhase 1/2
  • USOR Minnesota Oncology Hematology, Maplewood · 5 mi away
Ages 18 and older · All sexes · Updated Aug 4, 2026 · NCT05579366

Study of RAS(ON) Inhibitors in Combination With Ivonescimab in Patients With Solid Tumors

RecruitingPhase 1/2
  • Health Partners Cancer Center at Regions Hospital, Saint Paul
Ages 18 and older · All sexes · Updated Aug 3, 2026 · NCT07397338

Study of STK-012 Alone and With Other Treatments in Patients With Advanced Lung Cancer and Other Cancers

RecruitingPhase 1/2
  • HealthPartners Cancer Center at Regions Hospital, Saint Paul
Ages 18 and older · All sexes · Updated Jul 21, 2026 · NCT05098132

A Study of Sigvotatug Vedotin in Advanced Solid Tumors

RecruitingPhase 1
  • Allina Health Cancer Institute - United Hospital, Saint Paul
  • Allina Health Cancer Institute, Saint Paul
Ages 18 and older · All sexes · Updated Jul 6, 2026 · NCT04389632

Comparing Combinations of Targeted Drugs for Advanced Non-Small Cell Lung Cancer That Has EGFR and MET Gene Changes (A Lung-MAP Treatment Trial)

RecruitingPhase 2
  • Regions Hospital, Saint Paul
  • United Hospital, Saint Paul
Ages 18 and older · All sexes · Updated Jun 3, 2026 · NCT05642572

Adding the Immunotherapy Drug Cemiplimab to Usual Treatment for People With Advanced Non-Small Cell Lung Cancer Who Had Previous Treatment With Platinum Chemotherapy and Immunotherapy (An Expanded Lung-MAP Treatment Trial)

RecruitingPhase 2/3
  • Regions Hospital, Saint Paul
  • United Hospital, Saint Paul
  • Minnesota Oncology Hematology PA-Woodbury, Woodbury · 7 mi away
Ages 18 and older · All sexes · Updated May 5, 2026 · NCT06616584

Assessing Benefits and Harms of Cannabis/Cannabinoid Use Among Cancer Patients Treated in Community Oncology Clinics

RecruitingObservational study
  • Regions Hospital, Saint Paul
  • United Hospital, Saint Paul
  • Minnesota Oncology Hematology PA-Maplewood, Maplewood · 5 mi away
  • and 3 more
Ages 18 and older · All sexes · Updated Mar 17, 2026 · NCT06418204

A Phase 1/2a Study of DB-1311/BNT324 in Advanced/Metastatic Solid Tumors

RecruitingPhase 1/2
  • Research Site 121, Saint Paul
Ages 18 and older · All sexes · Updated Nov 21, 2025 · NCT05914116

Non-Small Cell Lung Cancer trials in other cities

Other studies in Saint Paul

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.