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Colorectal Cancer clinical trials in Atlanta, GA

29 studies for Colorectal Cancer are looking for participants at sites in and around Atlanta (within about 30 miles). Open a study to see who can join and how to contact the study team.

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A Phase 1 Study of PLN-101095 in Adults With Advanced or Metastatic Solid Tumors

RecruitingPhase 1
  • Winship Cancer Institute of Emory University, Atlanta
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT06270706

Testing the Addition of Total Ablative Therapy to Usual Systemic Therapy Treatment for Limited Metastatic Colorectal Cancer, ERASur Trial

RecruitingPhase 2
  • Grady Health System, Atlanta
  • Emory Proton Therapy Center, Atlanta
  • Emory University Hospital Midtown, Atlanta
  • and 2 more
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT05673148

Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection

RecruitingObservational studyHealthy volunteers welcome
  • Atlanta VA Medical Center, Decatur · 6 mi away
Ages 40 to 75 · All sexes · Updated Oct 2, 2026 · NCT05334069

A Study of Amivantamab and FOLFIRI Versus Cetuximab/Bevacizumab and FOLFIRI in Participants With KRAS/NRAS and BRAF Wild-type Colorectal Cancer Who Have Previously Received Chemotherapy

RecruitingPhase 3
  • Grady Memorial Hospital, Atlanta
  • Piedmont Cancer Institute, Atlanta
  • Winship Cancer Institute Emory University, Atlanta
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06750094

A Study of Amivantamab and mFOLFOX6 or FOLFIRI Versus Cetuximab and mFOLFOX6 or FOLFIRI as First-line Treatment in Participants With KRAS/NRAS and BRAF Wild-type Unresectable or Metastatic Left-sided Colorectal Cancer

RecruitingPhase 3
  • Grady Memorial Hospital, Atlanta
  • Winship Cancer Institute Emory University, Atlanta
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06662786

A Study to Evaluate the Safety, Pharmacokinetics, and Anti-Tumor Activity of VVD-133214 as Monotherapy and in Combination in Participants With Advanced Solid Tumors

RecruitingPhase 1
  • Emory University School of Medicine, Atlanta
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06004245

Testing Pump Chemotherapy in Addition to Standard of Care Chemotherapy Versus Standard of Care Chemotherapy Alone for Patients With Unresectable Colorectal Liver Metastases: The PUMP Trial

RecruitingPhase 3
  • Emory University Hospital/Winship Cancer Institute, Atlanta
  • Emory Saint Joseph's Hospital, Atlanta
Ages 18 and older · All sexes · Updated Sep 24, 2026 · NCT05863195

A Study of LY4257496 in Participants With Cancer (OMNIRAY)

RecruitingPhase 1
  • Emory University School of Medicine - Winship Cancer Institute, Atlanta
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07114601

Testing the Effectiveness of the Anti-cancer Drug Pidnarulex (CX-5461), in Combination With Another Anti-cancer Drug Cemiplimab (REGN2810), in Treating Refractory Microsatellite Stable Colorectal Cancer

RecruitingPhase 1/2
  • Emory University Hospital Midtown, Atlanta
  • Emory University Hospital/Winship Cancer Institute, Atlanta
  • Emory Saint Joseph's Hospital, Atlanta
Ages 18 and older · All sexes · Updated Sep 9, 2026 · NCT07147231

Phase III Study of Ivonescimab or Bevacizumab Combined With FOLFOX in Patients With Metastatic Colorectal Cancer

RecruitingPhase 3
  • Clinical Study Site, Atlanta
  • Clinical Study Site, Atlanta
Ages 18 and older · All sexes · Updated Sep 8, 2026 · NCT07228832

A Study of Sofe-M in Participants With Selected Advanced Solid Tumors

RecruitingPhase 1
  • Emory University, Atlanta
Ages 18 and older · All sexes · Updated Sep 4, 2026 · NCT06400472

Tegavivint for the Treatment of Recurrent or Refractory Solid Tumors, Including Lymphomas and Desmoid Tumors

RecruitingPhase 1/2
  • Children's Healthcare of Atlanta - Arthur M Blank Hospital, Atlanta
12 Months – 30 Years · All sexes · Updated Aug 25, 2026 · NCT04851119

MOONRAY-01, A Study of LY3962673 in Participants With KRAS G12D-Mutant Solid Tumors

RecruitingPhase 1
  • Emory University School of Medicine, Atlanta
Ages 18 and older · All sexes · Updated Aug 24, 2026 · NCT06586515

AMG 410 Alone and in Combination With Other Agents in Participants With KRAS Altered Advanced or Metastatic Solid Tumors

RecruitingPhase 1
  • Emory University, Atlanta
Ages 18 and older · All sexes · Updated Jul 30, 2026 · NCT07094113

A Study of Bispecific Antibody MCLA-158 in Patients With Advanced Solid Tumors

RecruitingPhase 1/2
  • Emory University, Atlanta
Ages 18 and older · All sexes · Updated Jul 29, 2026 · NCT03526835

A Study of Tucatinib With Trastuzumab and mFOLFOX6 Versus Standard of Care Treatment in First-line HER2+ Metastatic Colorectal Cancer

RecruitingPhase 3
  • Emory University Hospital Midtown, Atlanta
  • Emory University Hospital, Atlanta
  • Winship Cancer Institute, Atlanta
  • and 1 more
Ages 18 and older · All sexes · Updated Jul 22, 2026 · NCT05253651

A Study of CHS-114 (Tagmokitug) in Combination With Toripalimab and/or Other Treatments in Participants With Advanced Solid Tumors

RecruitingPhase 1
  • Winship Cancer Center - Emory University, Atlanta
Ages 18 and older · All sexes · Updated Jul 15, 2026 · NCT06657144

A Trial to Evaluate the Safety and Activity of Fruquintinib in Minority Populations With Advanced, Previously Treated Colorectal Cancer

RecruitingPhase 4
  • Emory University, Atlanta
Ages 18 and older · All sexes · Updated Jul 7, 2026 · NCT06562543

A Study to Find a Suitable Dose of ASP5834 in Adults With Solid Tumors

RecruitingPhase 1
  • Winship Cancer Institute at Emory University, Atlanta
Ages 18 and older · All sexes · Updated May 18, 2026 · NCT07094204

Study of RMC-6236 in Patients With Advanced Solid Tumors Harboring Specific Mutations in RAS

RecruitingPhase 1/2
  • Piedmont Healthcare, Atlanta
Ages 18 and older · All sexes · Updated May 15, 2026 · NCT05379985

Zanidatamab Before Surgery for the Treatment of HER2 Positive Colon and Rectal Cancer in Patients Planned for Curative Intent Treatment

RecruitingPhase 2
  • Emory University Hospital Midtown, Atlanta
  • Emory University Hospital, Atlanta
  • Emory Saint Joseph's Hospital, Atlanta
  • and 1 more
Ages 18 and older · All sexes · Updated Apr 17, 2026 · NCT07405476

Assessing Benefits and Harms of Cannabis/Cannabinoid Use Among Cancer Patients Treated in Community Oncology Clinics

RecruitingObservational study
  • Northside Hospital, Atlanta
Ages 18 and older · All sexes · Updated Mar 17, 2026 · NCT06418204

A Phase 1/2 Study to Evaluate CHM-2101, an Autologous Cadherin 17 Chimeric Antigen Receptor (CAR) T Cell Therapy

RecruitingPhase 1/2
  • Emory University, Atlanta
Ages 18 to 85 · All sexes · Updated Jan 29, 2026 · NCT06055439

LOTUS-CC: An Observational Research Study to Uncover Subtypes of Cancer Cachexia

RecruitingObservational study
  • Northside Hospital, Atlanta
Ages 18 and older · All sexes · Updated Jan 9, 2026 · NCT06073431

A Web-Based Dyadic Intervention for Colorectal Cancer

RecruitingHealthy volunteers welcome
  • Emory University/Winship Cancer Institute, Atlanta
Ages 18 and older · All sexes · Updated Dec 19, 2025 · NCT05663203

A Beta-only IL-2 ImmunoTherapY Study

RecruitingPhase 1/2
  • Emory - Winship Cancer Institute, Atlanta
Ages 18 and older · All sexes · Updated Jul 9, 2025 · NCT05086692

About Colorectal Cancer

Colorectal cancer starts in the colon or rectum. It may not cause symptoms at first. Screening tests can help find it early, when treatment is most effective.

More about Colorectal Cancer on MedlinePlus

Colorectal Cancer trials in other cities

Other studies in Atlanta

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.