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Pancreatic Cancer clinical trials in Rochester, MN

22 studies for Pancreatic Cancer are looking for participants at sites in and around Rochester (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

BMS-986340 in Combination With Nivolumab, Gemcitabine and Nab-paclitaxel for the Treatment of Metastatic and Recurrent Pancreatic Adenocarcinoma

RecruitingPhase 2
  • Mayo Clinic in Rochester, Rochester
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT07226856

A Study of IDE892 as Monotherapy and Combination in MTAP-deleted Advanced Solid Tumors

RecruitingPhase 1
  • Mayo Clinic Rochester, Rochester
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07277413

Solid Tumor Analysis for HLA Loss of Heterozygosity (LOH) and Apheresis for CAR T- Cell Manufacturing

RecruitingObservational study
  • Mayo Clinic Rochester, Rochester
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT04981119

A Study to Learn About the Medicine Ponsegromab in Adults With Cancer of the Pancreas Which Has Spread and Caused Significant Body Weight Loss and Fatigue

RecruitingPhase 2/3
  • Mayo Clinic Cancer Center Outpatient Pharmacy, Rochester
  • Mayo Clinic, Rochester
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06989437

Study of Daraxonrasib (RMC-6236) in Patients With Resected Pancreatic Ductal Adenocarcinoma (PDAC)

RecruitingPhase 3
  • Mayo Clinic Cancer Center, Rochester
Ages 18 and older · All sexes · Updated Sep 23, 2026 · NCT07252232

Study of RAS(ON) Inhibitors in Patients With Gastrointestinal Solid Tumors

RecruitingPhase 1/2
  • Mayo Clinic, Rochester
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT06445062

Pancreatic Cancer Detection Consortium (PCDC) Prospective Cohorts

RecruitingObservational study
  • Mayo Clinic in Rochester, Rochester
Ages 18 and older · All sexes · Updated Sep 21, 2026 · NCT06271291

A Study of Nuzefatide Pevedotin (BT5528) in Patients With Metastatic Pancreatic Ductal Adenocarcinoma (PDAC)

RecruitingPhase 2
  • Mayo Clinic Rochester, Rochester
Ages 18 and older · All sexes · Updated Sep 18, 2026 · NCT07450859

A Study of BMS-986504 Monotherapy and in Combination With Other Agents in Participants With Advanced and/or Metastatic Solid Tumors With Homozygous MTAP Deletion (MountainTAP-5)

RecruitingPhase 2
  • Local Institution - 0129, Rochester
  • Local Institution - 0174, Rochester
  • Local Institution - 0181, Rochester
Ages 18 and older · All sexes · Updated Sep 16, 2026 · NCT07492680

Hyperthermic Intraperitoneal Chemotherapy for the Treatment of Pancreatic Cancer and Peritoneal Metastasis

RecruitingPhase 2
  • Mayo Clinic in Rochester, Rochester
Ages 18 to 80 · All sexes · Updated Sep 14, 2026 · NCT04858009

CREO - Microwave Ablation Feasibility Study

Recruiting
  • Mayo Clinic Rochester, Rochester
Ages 18 and older · All sexes · Updated Sep 14, 2026 · NCT07817147

Comparing the Clinical Impact of Pancreatic Cyst Surveillance Programs and Associated Biomarkers

RecruitingObservational study
  • Mayo Clinic in Rochester, Rochester
Ages 50 to 75 · All sexes · Updated Sep 4, 2026 · NCT04239573

A Phase 2 Study of VS-7375 in Patients With KRAS G12D-Mutated Pancreatic Cancer

RecruitingPhase 2
  • Mayo Clinical Rochester, Rochester
Ages 18 and older · All sexes · Updated Sep 3, 2026 · NCT07644559

Phase 1 Study of MRTX1719 in Solid Tumors With MTAP Deletion

RecruitingPhase 1
  • Mayo Clinic, Rochester
Ages 18 and older · All sexes · Updated Sep 2, 2026 · NCT05245500

Investigational Scan (68Ga-FAPI-46 PET/CT) for Imaging of Cancer-Associated Fibroblasts for Localized Pancreatic Ductal Adenocarcinoma

RecruitingPhase 2
  • Mayo Clinic in Rochester, Rochester
Ages 18 and older · All sexes · Updated Aug 10, 2026 · NCT05518903

A Study to Evaluate the Safety and Efficacy of Mesothelin-Targeting Logic-gated CAR T, in Participants With Solid Tumors That Express MSLN and Have Lost HLA-A*02 Expression

RecruitingPhase 1/2
  • Mayo Clinic Rochester, Rochester
Ages 18 and older · All sexes · Updated Jun 12, 2026 · NCT06051695

A Prospective Registry for Patients at High-Risk for Pancreatic Cancer

RecruitingObservational studyHealthy volunteers welcome
  • Mayo Clinic in Rochester, Rochester
Ages 18 and older · All sexes · Updated Mar 10, 2026 · NCT06151223

Collecting Medical Information and Tissue Samples From Patients With Pancreatic Cancer or Other Pancreatic Disorders

RecruitingObservational study
  • Mayo Clinic in Rochester, Rochester
Ages 18 and older · All sexes · Updated Mar 9, 2026 · NCT00830557

A Phase II Nationwide, Fully Decentralized, Telemedicine Study of Pemigatinib in Adult Patients With Advanced or Metastatic Pancreatic Cancer With FGFR Genetic Alterations

RecruitingPhase 2
  • Ohio State University Telemedicine, Rochester
Ages 18 and older · All sexes · Updated Feb 17, 2026 · NCT06906562

cfDNA Assay Prospective Observational Validation for Early Cancer Detection and Minimal Residual Disease

RecruitingObservational studyHealthy volunteers welcome
  • Mayo Clinic, Rochester
Ages 40 and older · All sexes · Updated Jan 20, 2026 · NCT05366881

JAB-23E73 in Adult Participants With Advanced Solid Tumors With KRAS Alteration

RecruitingPhase 1/2
  • Mayo Clinic, Rochester
Ages 18 and older · All sexes · Updated Jan 16, 2026 · NCT06973564

A Phase 1 Study of XL309 (ISM3091) Alone and in Combination in Participants With Advanced Solid Tumors

RecruitingPhase 1
  • Exelixis Clinical Site #14, Rochester
Ages 18 and older · All sexes · Updated Sep 5, 2025 · NCT05932862

About Pancreatic Cancer

The pancreas is a gland behind your stomach that produces insulin. Pancreatic cancer is hard to catch early. Find out about risk factors and symptoms.

More about Pancreatic Cancer on MedlinePlus

Pancreatic Cancer trials in other cities

Other studies in Rochester

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.