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COVID-19 and Coronavirus Infections clinical trials in Boston, MA

5 studies for COVID-19 and Coronavirus Infections are looking for participants at sites in and around Boston (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

A Safety and Immunogenicity Trial of OCU500, ChAd36 Vector Encoding SARS-CoV-2 Spike Vaccine Via Intranasal and Inhalational Routes in Previously Vaccinated Adults

RecruitingPhase 1Healthy volunteers welcome
  • Brigham and Women's Hospital, Boston
Ages 18 to 64 · All sexes · Updated Oct 2, 2026 · NCT07536308

A Study to Learn About the Study Medicine Ibuzatrelvir in Adults With COVID-19 Who Are Severely Immunocompromised

RecruitingPhase 3
  • Brigham and Women's Hospital, Boston
  • Clinical Trials Center, Boston
  • Clinical Trials Hub, Boston
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT07013474

Randomized Double-Blind Placebo-Controlled Trial EValuating Baricitinib on PERSistent NEurologic and Cardiopulmonary Symptoms of Long COVID

RecruitingPhase 3
  • Brigham and Women's Hospital, Boston
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06631287

A Study to Learn About a Study Medicine Called Ibuzatrelvir in Adult and Adolescent Patients With COVID-19 Who Are Not Hospitalized But Are at Risk For Severe Disease

RecruitingPhase 3
  • Brigham and Women's Hospital, Boston
Ages 12 and older · All sexes · Updated Sep 25, 2026 · NCT06679140

Phase III DAS181 Lower Tract PIV Infection in Immunocompromised Subjects (Substudy: DAS181 for COVID-19): RCT Study

RecruitingPhase 3
  • Brigham and Women's Hospital, Boston
All ages · All sexes · Updated Jun 23, 2026 · NCT03808922

COVID-19 and Coronavirus Infections trials in other cities

Other studies in Boston

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.