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Cancer (all types) clinical trials in Springfield, MO

10 studies for Cancer (all types) are looking for participants at sites in and around Springfield (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

A Study of First-Line Olomorasib (LY3537982) and Pembrolizumab With or Without Chemotherapy in Patients With Advanced KRAS G12C-Mutant Non-small Cell Lung Cancer

RecruitingPhase 3
  • Oncology Hematology Associates, Springfield
Ages 18 and older · All sexes · Updated Sep 8, 2026 · NCT06119581

A Longitudinal Multi-Omic Biomarker Profiling Study of Patients With Head & Neck Squamous Cell Carcinoma (HNSCC)

RecruitingObservational study
  • Oncology Hematology Associates, Springfield
Ages 18 and older · All sexes · Updated Sep 3, 2026 · NCT06163534

Testing Olaparib for One or Two Years, With or Without Bevacizumab, to Treat Ovarian Cancer

RecruitingPhase 3
  • Mercy Hospital Springfield, Springfield
  • CoxHealth South Hospital, Springfield
Ages 18 and older · All sexes · Updated Aug 7, 2026 · NCT06580314

Predicting Response to Immunotherapy From Analysis of Live Tumor Biopsies (ELEPHAS-05)

RecruitingObservational study
  • Mercy Hospital - SPG, Springfield
Ages 18 and older · All sexes · Updated Jun 29, 2026 · NCT07327489

Galleri® in the Medicare Population.

RecruitingHealthy volunteers welcome
  • Mercy Health - Springfield, Springfield
Ages 50 and older · All sexes · Updated May 22, 2026 · NCT05673018

TEMPUS ARIES: A Biobank Registry Platform Study in Oncology

RecruitingObservational study
  • Oncology Hematology Associates, Springfield
Ages 18 to 99 · All sexes · Updated Feb 24, 2026 · NCT06207032

GEMINI-NSCLC: NSCLC Biomarker Study

RecruitingObservational study
  • Mercy Clinic Cancer and Hematology - Chub O'Reilly Cancer Center, Springfield
  • Oncology Hematology Associates, Springfield
Ages 18 and older · All sexes · Updated Feb 5, 2026 · NCT05236114

Tempus CRC Surveillance Study: A ctDNA Biomarker Profiling Study of Patients With CRC Using NGS Assays

RecruitingObservational study
  • Mercy Clinic Cancer and Hematology - Chub O'Reilly Cancer Center, Springfield
Ages 18 and older · All sexes · Updated May 6, 2025 · NCT05234177

Melanoma Margins Trial-II: 1cm v 2cm Wide Surgical Excision Margins for AJCC Stage II Primary Cutaneous Melanoma

Recruiting
  • Cox South Hospital, Springfield
Ages 18 and older · All sexes · Updated Nov 27, 2024 · NCT03860883

About Cancer (all types)

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Other studies in Springfield

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.