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Liver Cancer (Hepatocellular Carcinoma) clinical trials in Houston, TX

31 studies for Liver Cancer (Hepatocellular Carcinoma) are looking for participants at sites in and around Houston (within about 30 miles). Open a study to see who can join and how to contact the study team.

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A Study of ZW251 in Participants With Advanced Solid Tumors

RecruitingPhase 1
  • MD Anderson Cancer Center, Houston
Ages 18 and older · All sexes · Updated Oct 5, 2026 · NCT07164313

Study of the Theranostic Pair RYZ811 (Diagnostic) and RYZ801 (Therapeutic) to Identify and Treat Subjects With GPC3+ (Glypican-3) Unresectable HCC

RecruitingPhase 1/2
  • Research Facility, Houston
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT06726161

National Liver Cancer Screening Trial

RecruitingPhase 4
  • Baylor College of Medicine, Houston
Ages 18 to 85 · All sexes · Updated Sep 25, 2026 · NCT06084234

A Phase 1/2 Study of BGB-B2033, Alone or in Combination With Tislelizumab With or Without Bevacizumab, in Participants With Advanced or Metastatic Solid Tumors

RecruitingPhase 1/2
  • The University of Texas Md Anderson Cancer Center, Houston
Ages 18 and older · All sexes · Updated Sep 16, 2026 · NCT06427941

Nivolumab, Fluorouracil, and Interferon Alpha 2B for the Treatment of Unresectable Fibrolamellar Cancer

RecruitingPhase 1/2
  • M D Anderson Cancer Center, Houston
Ages 12 and older · All sexes · Updated Sep 14, 2026 · NCT04380545

Phase III Study of Rilvegostomig in Combination With Bevacizumab With or Without Tremelimumab as First-line Treatment of Hepatocellular Carcinoma

RecruitingPhase 3
  • Research Site, Houston
Ages 18 and older · All sexes · Updated Sep 3, 2026 · NCT06921785

Tegavivint for the Treatment of Recurrent or Refractory Solid Tumors, Including Lymphomas and Desmoid Tumors

RecruitingPhase 1/2
  • Baylor College of Medicine/Dan L Duncan Comprehensive Cancer Center, Houston
12 Months – 30 Years · All sexes · Updated Aug 25, 2026 · NCT04851119

FOG-001 in Locally Advanced or Metastatic Solid Tumors

RecruitingPhase 1/2
  • The University of Texas MD Anderson Cancer Center, Houston
Ages 18 and older · All sexes · Updated Aug 17, 2026 · NCT05919264

First in Human Study to Evaluate AZD9793 in Participants With Advanced or Metastatic Solid Tumours

RecruitingPhase 1/2
  • Research Site, Houston
Ages 18 and older · All sexes · Updated Aug 13, 2026 · NCT06795022

A Study of MGC026 in Participants With Advanced Solid Tumors

RecruitingPhase 1
  • The University of Texas MD Anderson Cancer Center, Houston
  • University of Texas Health Science Center at Houston, Houston
Ages 18 and older · All sexes · Updated Aug 11, 2026 · NCT06242470

IDOV-Immune for Advanced Solid Tumors

RecruitingPhase 1
  • MD Anderson Cancer Center, Houston
Ages 18 and older · All sexes · Updated Aug 5, 2026 · NCT06910657

A Study to Assess the Efficacy and Safety of FORE8394 in Participants With Cancer Harboring BRAF Alterations

RecruitingPhase 2
  • University of Texas MD Anderson Cancer Center, Houston
Ages 8 and older · All sexes · Updated Jul 27, 2026 · NCT05503797

A Study of PF-08046054/SGN-PDL1V in Advanced Solid Tumors

RecruitingPhase 1
  • The University of Texas MD Anderson Cancer Center Investigational Pharmacy Services, Houston
  • The University of Texas MD Anderson Cancer Center, Houston
Ages 18 and older · All sexes · Updated Jul 22, 2026 · NCT05208762

A Study to Evaluate ALN-BCAT in Patients With Hepatocellular Carcinoma

RecruitingPhase 1
  • Clinical Trial Site, Houston
Ages 18 and older · All sexes · Updated Jun 17, 2026 · NCT06600321

Preventing Liver Cancer Mortality Through Imaging With Ultrasound vs. MRI

Recruiting
  • Michael E. DeBakey VA Medical Center, Houston, TX, Houston
Ages 18 to 75 · All sexes · Updated Jun 17, 2026 · NCT05486572

A Trial Utilizing 18F-FS PG PET to Guide Therapy in Hepatocellular Carcinoma

RecruitingPhase 1
  • The University of Texas M. D. Anderson Cancer Center, Houston
Ages 18 and older · All sexes · Updated Jun 10, 2026 · NCT07116486

A Phase 1/1B Study of ST-01156, a Small Molecule RBM39 Degrader, in Patients With Advanced Solid Malignancies

RecruitingPhase 1
  • The University of Texas MD Anderson Cancer Center, Houston
Ages 16 and older · All sexes · Updated Jun 2, 2026 · NCT07197554

Short Stitch Versus Traditional Suture for the Prevention of Incisional Hernia After Open Hepatectomy

RecruitingPhase 2
  • M D Anderson Cancer Center, Houston
Ages 18 and older · All sexes · Updated May 26, 2026 · NCT04982653

High Dose-Rate Brachytherapy for the Treatment of Both Primary and Secondary Unresectable Liver Malignancies

Recruiting
  • M D Anderson Cancer Center, Houston
Ages 19 and older · All sexes · Updated May 22, 2026 · NCT05053555

DB-1311 in Combination With BNT327 or DB-1305 in Advanced/Metastatic Solid Tumors

RecruitingPhase 2
  • USA12-0, Houston
Ages 18 and older · All sexes · Updated May 22, 2026 · NCT06953089

A Study of TTI-101 as Monotherapy and in Combination in Participants With Locally Advanced or Metastatic, and Unresectable Hepatocellular Carcinoma

RecruitingPhase 1/2
  • University of Texas MD Anderson Cancer Center, Houston
Ages 18 and older · All sexes · Updated Apr 27, 2026 · NCT05440708

Impact of "Teaching the Teachers" Concept on Global Education and Application of Hepatocellular Carcinoma Diagnosis Guidelines

RecruitingObservational studyHealthy volunteers welcome
  • M D Anderson Cancer Center, Houston
All ages · All sexes · Updated Apr 15, 2026 · NCT05143619

A Study of Oral 7HP349 (Alintegimod) in Combination With Ipilimumab Followed by Nivolumab Monotherapy

RecruitingPhase 1/2
  • MD Anderson Cancer Center, Houston
Ages 18 and older · All sexes · Updated Apr 13, 2026 · NCT06362369

Study of RP2 in Combination With Second-line Therapy in Patients With Locally Advanced or Metastatic HCC

RecruitingPhase 2
  • Houston Methodist Hospital Cancer Center, Houston
Ages 18 and older · All sexes · Updated Apr 2, 2026 · NCT05733598

Checkpoint Inhibition In Pediatric Hepatocellular Carcinoma

RecruitingPhase 2
  • Baylor College of Medicine, Houston
Ages 0 to 30 · All sexes · Updated Feb 24, 2026 · NCT04134559

Zanzalintinib (XL-092) Plus Durvalumab and Tremelimumab in Unresectable Hepatocellular Carcinoma (ZENOBIA)

RecruitingPhase 2
  • Houston Methodist Neal Cancer Center, Houston
Ages 18 and older · All sexes · Updated Nov 6, 2025 · NCT06698250

Immunotherapy For Adults With GPC3-Positive Solid Tumors Using IL-15 and IL-21 Armored GPC3-CAR T Cells

RecruitingPhase 1
  • Houston Methodist Hospital, Houston
Up to age 21 · All sexes · Updated Nov 3, 2025 · NCT06198296

SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

RecruitingObservational study
  • Massive Bio SYNERGY-AI site, Houston
All ages · All sexes · Updated Oct 28, 2025 · NCT03452774

Atezolizumab and Bevacizumab Pre-Liver Transplantation for Patients With Hepatocellular Carcinoma Beyond Milan Criteria

RecruitingPhase 4
  • Houston Methodist Research Institute, Houston
Ages 18 and older · All sexes · Updated Feb 1, 2023 · NCT05185505

Liver Cancer (Hepatocellular Carcinoma) trials in other cities

Other studies in Houston

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.