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Multiple Myeloma clinical trials in St. Louis, MO

24 studies for Multiple Myeloma are looking for participants at sites in and around St. Louis (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

A Study Evaluating the Prophylactic Use of Tocilizumab to Prevent Cytokine Release Syndrome With Ramantamig Administration in Participants With Relapsed/Refractory Multiple Myeloma

RecruitingPhase 2
  • Washington University School Of Medicine, St Louis
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT07589634

A Study of Talquetamab in Participants With Relapsed or Refractory Multiple Myeloma

RecruitingPhase 2
  • Washington University School Of Medicine, St Louis
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT04634552

A Long-term Study for Participants Previously Treated With Ciltacabtagene Autoleucel

RecruitingPhase 4
  • Washington University School Of Medicine, St Louis
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT05201781

Collection of Tissue Samples for Cancer Research

RecruitingObservational study
  • Washington University - St. Louis, St Louis
2 Months · All sexes · Updated Sep 16, 2026 · NCT00900198

Study of Arlocabtagene Autoleucel (BMS-986393) a GPRC5D-directed CAR T Cell Therapy in Adult Participants With Relapsed or Refractory Multiple Myeloma

RecruitingPhase 2
  • Washington University School of Medicine, St Louis
Ages 18 and older · All sexes · Updated Sep 14, 2026 · NCT06297226

A Study of Gammagard Liquid (Immune Globulin Infusion, 10%) to Prevent Infections in Adults With Multiple Myeloma

RecruitingPhase 3
  • Washington University School of Medicine, St Louis
Ages 18 and older · All sexes · Updated Sep 9, 2026 · NCT06980480

A Modular, Phase I/II, Multicentre Study to Evaluate AZD4045, in Participants With Relapsed or Refractory Multiple Myeloma

RecruitingPhase 1/2
  • Research Site, St Louis
Ages 18 and older · All sexes · Updated Aug 27, 2026 · NCT07681596

A Study to Evaluate the Efficacy and Safety of Belantamab Mafodotin in Combination With Standard of Care in Participants With Relapsed-Refractory Multiple Myeloma (RRMM)

RecruitingPhase 2
  • GSK Investigational Site, Bridgeton · 15 mi away
Ages 18 and older · All sexes · Updated Aug 25, 2026 · NCT07227311

Testing the Use of Combination Therapy in Adult Patients With Newly Diagnosed Multiple Myeloma, the EQUATE Trial

RecruitingPhase 3
  • Mercy Infusion Center - Chippewa, St Louis
  • Mercy Hospital South, St Louis
  • Missouri Baptist Medical Center, St Louis
  • and 4 more
Ages 18 and older · All sexes · Updated Aug 19, 2026 · NCT04566328

Study of AZD0120 in Newly Diagnosed Multiple Myeloma Ineligible for ASCT

RecruitingPhase 3
  • Research Site, St Louis
Ages 18 and older · All sexes · Updated Aug 14, 2026 · NCT07764978

Measurable Residual Disease-Guided Post-Transplant Elranatamab Maintenance

RecruitingPhase 2
  • Washington University School of Medicine, St Louis
Ages 18 and older · All sexes · Updated Aug 6, 2026 · NCT06483100

A Study to Evaluate the Efficacy of Cemsidomide + Dexamethasone in Participants With Relapsed/Refractory Multiple Myeloma

RecruitingPhase 2
  • Washington University/Siteman Cancer Center, St Louis
Ages 18 and older · All sexes · Updated Aug 6, 2026 · NCT07284758

Recombinant Human IL-7 (NT-I7) in Relapsed/Refractory Multiple Myeloma Following BCMA CAR-T Therapy (Cilta-cel)

RecruitingPhase 1
  • Washington University School of Medicine, St Louis
Ages 18 and older · All sexes · Updated Jul 21, 2026 · NCT07200089

Washington University Participant Engagement and Cancer Genomic Sequencing Center (WU-PE-CGS)

Recruiting
  • Washington University School of Medicine, St Louis
Ages 18 and older · All sexes · Updated Jul 14, 2026 · NCT06340646

Safety and Efficacy of CS1 CAR-T (WS-CART-CS1) in Subjects With Multiple Myeloma

RecruitingPhase 1
  • Washington University School of Medicine, St Louis
Ages 18 and older · All sexes · Updated Jul 9, 2026 · NCT06185751

64Cu-LLP2A for Imaging Hematologic Malignancies

RecruitingEarly phase 1Healthy volunteers welcome
  • Washington University School of Medicine, St Louis
Ages 18 and older · All sexes · Updated Jun 17, 2026 · NCT06636175

Comparing Combinations of Drugs to Treat Newly Diagnosed Multiple Myeloma (NDMM) When a Stem Cell Transplant is Not a Medically Suitable Treatment

RecruitingPhase 3
  • Saint Louis Cancer and Breast Institute-South City, St Louis
  • Mercy Hospital South, St Louis
  • Missouri Baptist Medical Center, St Louis
  • and 5 more
All ages · All sexes · Updated Jun 10, 2026 · NCT05561387

Selinexor Maintenance Post CAR-T Cell Therapy for Multiple Myeloma

RecruitingPhase 1
  • Washington University School of Medicine, St Louis
Ages 18 and older · All sexes · Updated Jun 8, 2026 · NCT07200102

An AI-Generated, Personalized Question Prompt List Intervention for Patients With Hematologic Cancers

Recruiting
  • Washington University School of Medicine, St Louis
Ages 18 to 99 · All sexes · Updated Jun 1, 2026 · NCT07226934

Post-Op Pain Control for Prophylactic Intramedullary Nailing.

RecruitingPhase 3
  • Saint Louis University, St Louis
Ages 18 and older · All sexes · Updated Apr 22, 2026 · NCT03823534

Lymphodepleting Total Body Irradiation (TBI) Plus Cyclophosphamide Prior to Ciltacabtagene Autoleucel (Carvykti; Cilta-cel) for Multiple Myeloma (MM) Patients With Impaired Renal Function

RecruitingPhase 1
  • Washington University School of Medicine, St Louis
Ages 18 and older · All sexes · Updated Mar 11, 2026 · NCT06623630

About Multiple Myeloma

Multiple myeloma is a cancer that begins in plasma cells, a type of white blood cell. Discover symptoms, diagnostic tests, and treatments for myeloma.

More about Multiple Myeloma on MedlinePlus

Multiple Myeloma trials in other cities

Other studies in St. Louis

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.