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Breast Cancer clinical trials in Charleston, SC

12 studies for Breast Cancer are looking for participants at sites in and around Charleston (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

CBD for Breast Cancer Primary Tumors

RecruitingPhase 1
  • Medical University of South Carolina, Charleston
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT06148038

A Clinical Study of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) in People With Breast Cancer (MK-2870-032)

RecruitingPhase 3
  • Medical University of South Carolina-Hollings Cancer Center ( Site 0016), Charleston
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06966700

A Study of Tersolisib (LY4064809/STX-478) With Other Anti-Cancer Treatments in Participants With Advanced Breast Cancer With a Genetic Change (PIK3CA)

RecruitingPhase 3
  • Medical University of South Carolina, Charleston
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07174336

A Study of Elacestrant Versus Standard Endocrine Therapy in Women and Men With ER+,HER2-, Early Breast Cancer With High Risk of Recurrence

RecruitingPhase 3
  • Hollings Cancer Center, Charleston
Ages 18 and older · All sexes · Updated Sep 15, 2026 · NCT06492616

E-Mindfulness Approaches for Living After Breast Cancer

RecruitingPhase 3
  • Medical University of South Carolina, Charleston
Ages 18 to 50 · All sexes · Updated Aug 4, 2026 · NCT06748222

Finding the Best Tamoxifen Dose for Breast Cancer Risk Reduction in Premenopausal Women, RENAISSANCE Trial

RecruitingPhase 2
  • Medical University of South Carolina, Charleston
Ages 18 to 55 · Women · Updated Jul 27, 2026 · NCT06184750

Sacituzumab Govitecan +/- Pembrolizumab in Metastatic TNBC

RecruitingPhase 2
  • Medical University of South Carolina, Charleston
Ages 18 and older · All sexes · Updated Apr 29, 2026 · NCT04468061

De-Escalation of Breast Radiation Trial for Hormone Sensitive, HER-2 Negative, Oncotype Recurrence Score Less Than or Equal to 18 Breast Cancer (DEBRA)

RecruitingPhase 3
  • Medical University of South Carolina, Charleston
Ages 50 to 70 · All sexes · Updated Apr 23, 2026 · NCT04852887

Assessing Benefits and Harms of Cannabis/Cannabinoid Use Among Cancer Patients Treated in Community Oncology Clinics

RecruitingObservational study
  • Medical University of South Carolina, Charleston
Ages 18 and older · All sexes · Updated Mar 17, 2026 · NCT06418204

cfDNA Assay Prospective Observational Validation for Early Cancer Detection and Minimal Residual Disease

RecruitingObservational studyHealthy volunteers welcome
  • Medical University of South Carolina, Charleston
Ages 40 and older · All sexes · Updated Jan 20, 2026 · NCT05366881

MammaPrint, BluePrint, and Full-genome Data Linked With Clinical Data to Evaluate New Gene EXpression Profiles

RecruitingObservational study
  • Roper St. Francis Physician Partners - Breast Surgery, Charleston
Ages 18 and older · All sexes · Updated Aug 20, 2025 · NCT03053193

About Breast Cancer

Breast cancer is a cancer that starts in the breast tissue, when cells change and grow out of control. These extra cells can form a mass called a tumor.

More about Breast Cancer on MedlinePlus

Breast Cancer trials in other cities

Other studies in Charleston

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.