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Chronic Lymphocytic Leukemia clinical trials in Rochester, MN

19 studies for Chronic Lymphocytic Leukemia are looking for participants at sites in and around Rochester (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

Acalabrutinib With or Without Obinutuzumab in Treating Patients With Early-Stage Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma

RecruitingPhase 2
  • Mayo Clinic in Rochester, Rochester
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT03516617

A Study to Evaluate Safety, PK, PD and Efficacy of AZD5492, a T Cell-engaging Antibody Targeting CD20 in Subjects With R/R B-Cell Malignancies.

RecruitingPhase 1/2
  • Research Site, Rochester
Ages 18 and older · All sexes · Updated Sep 30, 2026 · NCT06542250

A Dose-Escalation and Expansion Study of Tacabrutideg (BGB-16673) in Participants With B-Cell Malignancies

RecruitingPhase 1/2
  • Mayo Clinic Rochester, Rochester
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT05006716

Study of SLS009 (Formerly GFH009) a Potent Highly Selective CDK9 Inhibitor in Patients With Hematologic Malignancies and High-Risk Newly Diagnosed AML

RecruitingPhase 1/2
  • Mayo Clinic, Rochester
Ages 12 and older · All sexes · Updated Sep 3, 2026 · NCT04588922

Gene Therapy for CD19-Positive Hematologic Malignancies (SENTRY-CD19)

RecruitingPhase 1/2
  • Mayo Clinic, Clinical Trials Referral Office, Rochester
Ages 13 to 90 · All sexes · Updated Aug 6, 2026 · NCT06533579

A Study of Emavusertib + An Approved Bruton Tyrosine Kinase Inhibitor (BTKi) in Participants With Chronic Lymphocytic Leukemia (CLL) and Other B-cell Malignancies

RecruitingPhase 2
  • Mayo Clinic, Rochester
Ages 18 and older · All sexes · Updated Jun 12, 2026 · NCT07271667

CD19-Directed CAR-T Cell Therapy for the Treatment of Relapsed/Refractory B Cell Malignancies

RecruitingPhase 1
  • Mayo Clinic in Rochester, Rochester
Ages 18 and older · All sexes · Updated Jun 9, 2026 · NCT04892277

The Effects of Exercise on Immune Phenotype of Indolent Non-Hodgkin Lymphoma and Chronic Lymphocytic Leukemia Patients

RecruitingHealthy volunteers welcome
  • Mayo Clinic in Rochester, Rochester
Ages 18 to 80 · All sexes · Updated Apr 9, 2026 · NCT05876923

Hematopoiesis in MBL and CLL Versus Healthy Age-Matched Control Subjects

RecruitingObservational studyHealthy volunteers welcome
  • Mayo Clinic in Rochester, Rochester
Ages 40 and older · All sexes · Updated Mar 31, 2026 · NCT06536452

Acalabrutinib, Venetoclax and Durvalumab for the Treatment of Richter Transformation From Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma

RecruitingPhase 2
  • Mayo Clinic in Rochester, Rochester
Ages 18 and older · All sexes · Updated Mar 25, 2026 · NCT05388006

A Study of (LY3527727) Pirtobrutinib in Participants With Previously Treated Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma or Non-Hodgkin Lymphoma

RecruitingPhase 4
  • Mayo Clinic- Minnesota, Rochester
Ages 18 and older · All sexes · Updated Mar 2, 2026 · NCT06876662

A Master Protocol to Evaluate the Long-Term Safety of (LY3527727) Pirtobrutinib

RecruitingPhase 4
  • Mayo Clinic- Minnesota, Rochester
Ages 18 and older · All sexes · Updated Mar 2, 2026 · NCT06876649

Family Study of Lymphoproliferative Disorders

RecruitingObservational studyHealthy volunteers welcome
  • Mayo Clinic, Rochester
Ages 18 to 100 · All sexes · Updated Oct 14, 2025 · NCT00626496

Q702 for the Treatment of Patients With Hematologic Malignancies

RecruitingPhase 1
  • Mayo Clinic in Rochester, Rochester
Ages 18 and older · All sexes · Updated Oct 10, 2025 · NCT06712810

Chronic Lymphocytic Leukemia trials in other cities

Other studies in Rochester

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.