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Coronary Artery Disease clinical trials in Boston, MA

16 studies for Coronary Artery Disease are looking for participants at sites in and around Boston (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

Combined Dose-Finding and CV Outcomes Study With CSL300 (Clazakizumab) in Adult Subjects With ESKD Undergoing Dialysis (POSIBIL6ESKD)

RecruitingPhase 2/3
  • Tufts Medical Center, Boston
  • Massachusetts General Hospital, Boston
Ages 18 and older · All sexes · Updated Sep 21, 2026 · NCT05485961

Product Surveillance Registry

RecruitingObservational study
  • Boston, Boston
All ages · All sexes · Updated Sep 18, 2026 · NCT01524276

Investigational Trial to Evaluate XC001 Delivered Via an Cardiac Catheter in Subjects With Chronic Angina.

RecruitingPhase 2
  • Massachusetts General Hospital, Boston
Ages 18 to 85 · All sexes · Updated Sep 11, 2026 · NCT07048808

REvascularization CHoices Among Under-Represented Groups Evaluation: The RECHARGE Trial - Minorities

RecruitingPhase 3
  • Massachusetts General Hospital, Boston
Ages 18 and older · All sexes · Updated Sep 8, 2026 · NCT06399705

REvascularization CHoices Among Under-Represented Groups Evaluation: The RECHARGE Trial - Women

RecruitingPhase 3
  • Massachusetts General Hospital, Boston
Ages 18 and older · All sexes · Updated Sep 8, 2026 · NCT06399692

Prospective Global Registry for the Study of Chronic Total Occlusion Intervention

RecruitingObservational study
  • Massachusetts General Hospital, Boston
  • Beth Israel Deaconess Medical Center, Boston
All ages · All sexes · Updated Aug 19, 2026 · NCT02061436

Safety and Effectiveness of the Orsiro Mission 48-mm Sirolimus Eluting Coronary Stent System in Subjects With Coronary Artery Lesions

Recruiting
  • Massachusetts General Hospital, Boston
Ages 18 and older · All sexes · Updated Jul 24, 2026 · NCT06779630

ANDREAS Registry (Assessment of Novel Drug-coated Balloon Revascularization: Effectiveness, Angiographic Outcomes, and Safety)

RecruitingObservational study
  • Tufts Medical Center, Boston
  • Brigham and Women's Hospital, Boston
Ages 18 and older · All sexes · Updated Jun 15, 2026 · NCT07559903

Physiological Assessment of Severe Coronary Stenosis for Informing Planned PCI

RecruitingObservational study
  • Beth Israel Deaconess Medical Center, Boston
Ages 18 and older · All sexes · Updated Jun 11, 2026 · NCT05491668

Impact of Disclosing Coronary Artery Disease Polygenic Risk Score on Cardiovascular Health

Recruiting
  • Massachusetts General Hospital, Boston
Ages 30 to 75 · All sexes · Updated Mar 23, 2026 · NCT07087431

AI Detection of Incidental Coronary Artery Calcium to Enhance Cardiovascular Disease Prevention

Recruiting
  • Brigham and Women's Hospital, Boston
Ages 40 to 75 · All sexes · Updated Jan 23, 2026 · NCT06235112

Investigation of Metformin in Pre-Diabetes on Atherosclerotic Cardiovascular OuTcomes

RecruitingPhase 4
  • VA Boston Healthcare System Jamaica Plain Campus, Jamaica Plain, MA, Boston
Ages 18 and older · All sexes · Updated Dec 17, 2025 · NCT02915198

The Impact of Renal Transplant on Coronary Microvascular Function Among Patients With Advanced Chronic Kidney Disease

RecruitingObservational study
  • Brigham and Women's Hospital, Boston
Ages 18 and older · All sexes · Updated Oct 30, 2025 · NCT07222683

Staged Complete Revascularization for Coronary Artery Disease vs Medical Management Alone in Patients With AS Undergoing Transcatheter Aortic Valve Replacement

Recruiting
  • Tufts Medical, Boston
  • Massachusetts General Hospital, Boston
All ages · All sexes · Updated Jul 24, 2025 · NCT04634240

MagicTouch for Treatment of In-Stent Restenosis in Coronary Artery Lesions

Recruiting
  • Beth Israel Deaconess Medical Center, Boston
Ages 18 to 110 · All sexes · Updated Feb 25, 2025 · NCT05908331

About Coronary Artery Disease

Coronary artery disease (CAD) is the most common type of heart disease. It can lead to angina and heart attack. Read about symptoms and tests.

More about Coronary Artery Disease on MedlinePlus

Coronary Artery Disease trials in other cities

Other studies in Boston

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.