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Endometrial Cancer clinical trials in Durham, NC

16 studies for Endometrial Cancer are looking for participants at sites in and around Durham (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

Tirzepatide in Obesity-Driven Endometrial Cancer

RecruitingEarly phase 1
  • Lineberger Comprehensive Cancer Center, Chapel Hill · 10 mi away
Ages 18 and older · Women · Updated Oct 2, 2026 · NCT07065552

Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Advanced Solid Tumors, The ComboMATCH Screening Trial

RecruitingPhase 2
  • Duke University Medical Center, Durham
All ages · All sexes · Updated Oct 2, 2026 · NCT05564377

The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)

RecruitingPhase 1/2
  • Duke University, Durham
Ages 12 and older · All sexes · Updated Oct 2, 2026 · NCT04585750

Testing the Addition of an Antiangiogenic Drug (Bevacizumab) to Chemotherapy (Carboplatin and Paclitaxel) Combined With Immunotherapy (Pembrolizumab) for pMMR, TP53 Mutated Endometrial Cancer

RecruitingPhase 3
  • Duke University Medical Center, Durham
  • UNC Lineberger Comprehensive Cancer Center, Chapel Hill · 10 mi away
Ages 18 and older · Women · Updated Oct 2, 2026 · NCT07198074

Testing Nivolumab With or Without Ipilimumab in Deficient Mismatch Repair System (dMMR) Recurrent Endometrial Carcinoma

RecruitingPhase 2
  • Duke University Medical Center, Durham
Ages 18 and older · Women · Updated Sep 28, 2026 · NCT05112601

DESTINY-PANTUMOUR04

RecruitingObservational study
  • Research Site, Durham
Ages 18 to 130 · All sexes · Updated Sep 25, 2026 · NCT07124000

Adjuvant Therapy in POLE-Mutated and p53-Wildtype/NSMP Early Stage Endometrial Cancer RAINBO BLUE & TAPER

RecruitingPhase 2
  • Duke University Medical Center, Durham
  • UNC Lineberger Comprehensive Cancer Center, Chapel Hill · 10 mi away
Ages 18 and older · Women · Updated Sep 24, 2026 · NCT05640999

ORACLE: Observation of ResiduAl Cancer With Liquid Biopsy Evaluation

RecruitingObservational study
  • UNC- Chapel Hill, Chapel Hill · 10 mi away
Ages 18 and older · All sexes · Updated Sep 14, 2026 · NCT05059444

Study to Assess the Efficacy and Safety of Rina-S Compared to Treatment of Investigator's Choice in Participants With Endometrial Cancer

RecruitingPhase 3
  • Duke Cancer Institute, Durham
Ages 18 and older · Women · Updated Sep 9, 2026 · NCT07166094

A Phase 1 Study of CTIM-76 in Patients With Recurring Ovarian Cancer and Other Advanced Solid Tumors

RecruitingPhase 1
  • Duke Cancer Institute, Durham
Ages 18 and older · All sexes · Updated Sep 3, 2026 · NCT06515613

FOG-001 in Locally Advanced or Metastatic Solid Tumors

RecruitingPhase 1/2
  • Duke University, Durham
Ages 18 and older · All sexes · Updated Aug 17, 2026 · NCT05919264

A Study of PHST001 in Advanced Solid Tumors

RecruitingPhase 1
  • Duke Cancer Institute, Durham
Ages 18 and older · All sexes · Updated Aug 12, 2026 · NCT06840886

ONC201 and Atezolizumab in Obesity-Driven Endometrial Cancer

RecruitingPhase 1
  • Lineberger Comprehensive Cancer Center, Chapel Hill · 10 mi away
Ages 18 and older · Women · Updated Jan 29, 2026 · NCT05542407

Multimedia Aid for Genetic Testing in Gynecologic Oncology

Recruiting
  • Univeristy of North Carolina at Chapel Hill, Chapel Hill · 10 mi away
Ages 18 and older · Women · Updated Nov 12, 2025 · NCT07084168

SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

RecruitingObservational study
  • Massive Bio SYNERGY-AI site, Chapel Hill · 10 mi away
All ages · All sexes · Updated Oct 28, 2025 · NCT03452774

Endometrial Cancer trials in other cities

Other studies in Durham

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.