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Lung Diseases clinical trials in Durham, NC

13 studies for Lung Diseases are looking for participants at sites in and around Durham (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

Efficacy and Safety of Tozorakimab in Patients Hospitalised for Viral Lung Infection Requiring Supplemental Oxygen

RecruitingPhase 3
  • Research Site, Durham
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT05624450

Neladalkib (NVL-655) for TKI-naive Patients With Advanced ALK-Positive NSCLC

RecruitingPhase 3
  • Duke Cancer Center, Durham
Ages 18 and older · All sexes · Updated Sep 30, 2026 · NCT06765109

A Study to Learn About the Study Medicine Ibuzatrelvir in Adults With COVID-19 Who Are Severely Immunocompromised

RecruitingPhase 3
  • Duke Vaccine and Trials Unit, Durham
  • Duke Vaccine and Trials Unit, Durham
  • Duke University - Main Hospital and Clinics, Durham
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT07013474

American Lung Association (ALA) Lung Health Cohort

RecruitingObservational studyHealthy volunteers welcome
  • Duke University, Durham
Ages 25 to 35 · All sexes · Updated Sep 23, 2026 · NCT04543461

A Study of the Efficacy and Safety of Belimumab in Adults With Interstitial Lung Disease Associated With Connective Tissue Disease

RecruitingPhase 3
  • GSK Investigational Site, Durham
Ages 18 and older · All sexes · Updated Sep 8, 2026 · NCT06572384

A Study of First-Line Olomorasib (LY3537982) and Pembrolizumab With or Without Chemotherapy in Patients With Advanced KRAS G12C-Mutant Non-small Cell Lung Cancer

RecruitingPhase 3
  • Duke Cancer Institute, Durham
  • University of North Carolina Medical Center, Chapel Hill · 10 mi away
Ages 18 and older · All sexes · Updated Sep 8, 2026 · NCT06119581

A Study to Learn About a COVID-19 Vaccine in Healthy Adults 18 Through 64 Years of Age

RecruitingPhase 4Healthy volunteers welcome
  • Duke Vaccine and Trials Unit, Durham
Ages 18 to 64 · All sexes · Updated Aug 7, 2026 · NCT07730450

H01 in Adults With Interstitial Lung Disease (The SOLIS Study)

RecruitingPhase 2
  • NIEHS Clinical Research Unit (CRU), Research Triangle Park · 7 mi away
Ages 18 to 100 · All sexes · Updated Jul 28, 2026 · NCT06325696

Deep Functional Phenotyping of the ALA Lung Health Cohort

RecruitingObservational studyHealthy volunteers welcome
  • Duke University, Durham
Ages 25 to 35 · All sexes · Updated Jul 17, 2026 · NCT06177717

Autologous LN-145 in Patients With Metastatic Non-Small-Cell Lung Cancer

RecruitingPhase 2
  • University of North Carolina, Chapel Hill · 10 mi away
Ages 18 to 70 · All sexes · Updated Jun 26, 2026 · NCT04614103

Veterans Affairs Lung Cancer Surgery Or Stereotactic Radiotherapy

Recruiting
  • Durham VA Medical Center, Durham, NC, Durham
Ages 18 and older · All sexes · Updated Feb 19, 2026 · NCT02984761

Hyperpolarized 129Xe MRI for Imaging Pulmonary Function

RecruitingPhase 2Healthy volunteers welcome
  • Duke University Medical Center, Durham
Ages 18 and older · All sexes · Updated Jan 16, 2026 · NCT01280994

A Study to Evaluate Vimseltinib in Adults With Active Chronic Graft-Versus-Host Disease (cGVHD)

RecruitingPhase 2
  • Duke University Hospital, Durham
Ages 18 and older · All sexes · Updated Dec 15, 2025 · NCT06619561

About Lung Diseases

Lung diseases are disorders or infections that affect the lungs and cause breathing problems. Some can lead to respiratory failure. Find out more about prevention, living with lung diseases, and treatment.

More about Lung Diseases on MedlinePlus

Lung Diseases trials in other cities

Other studies in Durham

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.