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Melanoma clinical trials in Washington, DC

17 studies for Melanoma are looking for participants at sites in and around Washington (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

Clinical, Laboratory, and Epidemiologic Characterization of Individuals and Families at High Risk of Melanoma

RecruitingObservational studyHealthy volunteers welcome
  • National Cancer Institute (NCI), Bethesda · 7 mi away
  • National Institutes of Health Clinical Center, Bethesda · 7 mi away
4 Weeks – 99 Years · All sexes · Updated Oct 2, 2026 · NCT00040352

Phase II Trial of Combination Anti-PD-1 and Aldesleukin for Metastatic Melanoma and Renal Cell Carcinoma

RecruitingPhase 2
  • National Institutes of Health Clinical Center, Bethesda · 7 mi away
Ages 18 to 120 · All sexes · Updated Oct 2, 2026 · NCT05155033

Evaluation for NCI Surgery Branch Clinical Research Protocols

RecruitingObservational study
  • National Institutes of Health Clinical Center, Bethesda · 7 mi away
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT00001823

Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection

RecruitingObservational studyHealthy volunteers welcome
  • MedStar Georgetown University Hospital, Washington D.C.
  • MedStar Washington Hospital Center, Washington D.C.
  • Walter Reed National Military Medical Center, Bethesda · 7 mi away
Ages 40 to 75 · All sexes · Updated Oct 2, 2026 · NCT05334069

Study to Investigate Lifileucel Regimen Plus Pembrolizumab Compared With Pembrolizumab Alone in Participants With Untreated Advanced Melanoma.

RecruitingPhase 3
  • National Cancer Institute, Bethesda · 7 mi away
Ages 18 to 70 · All sexes · Updated Sep 24, 2026 · NCT05727904

A Study of Therapeutic Drug Monitoring-Based Atezolizumab Dosing

RecruitingPhase 1
  • National Institutes of Health Clinical Center, Bethesda · 7 mi away
Ages 18 to 120 · All sexes · Updated Sep 22, 2026 · NCT06066138

Immunotherapy in Combination With Prednisone and Sirolimus for Kidney Transplant Recipients With Unresectable or Metastatic Skin Cancer

RecruitingPhase 1/2
  • Sibley Memorial Hospital, Washington D.C.
Ages 18 and older · All sexes · Updated Aug 31, 2026 · NCT05896839

Project: Every Child for Younger Patients With Cancer

RecruitingObservational study
  • MedStar Georgetown University Hospital, Washington D.C.
  • Children's National Medical Center, Washington D.C.
  • Walter Reed National Military Medical Center, Bethesda · 7 mi away
Up to age 25 · All sexes · Updated Aug 25, 2026 · NCT02402244

Tegavivint for the Treatment of Recurrent or Refractory Solid Tumors, Including Lymphomas and Desmoid Tumors

RecruitingPhase 1/2
  • Children's National Medical Center, Washington D.C.
12 Months – 30 Years · All sexes · Updated Aug 25, 2026 · NCT04851119

A Phase 2 Trial for Metastatic Melanoma Using Adoptive Cell Therapy With Tumor Infiltrating Lymphocytes Plus IL-2 Either Alone or Following the Administration of Pembrolizumab

RecruitingPhase 2
  • National Institutes of Health Clinical Center, Bethesda · 7 mi away
Ages 18 to 72 · All sexes · Updated Aug 20, 2026 · NCT02621021

Administering Peripheral Blood Lymphocytes Transduced With a CD70-Binding Chimeric Antigen Receptor to People With CD70 Expressing Cancers

RecruitingPhase 1/2
  • National Institutes of Health Clinical Center, Bethesda · 7 mi away
Ages 18 to 72 · All sexes · Updated Aug 13, 2026 · NCT02830724

A Study of a Selective T Cell Receptor (TCR) Targeting, Bifunctional Antibody-fusion Molecule STAR0602 in Participants With Advanced Solid Tumors

RecruitingPhase 1/2
  • National Institutes of Health, Bethesda · 7 mi away
Ages 18 and older · All sexes · Updated Aug 11, 2026 · NCT05592626

DB-1311 in Combination With BNT327 or DB-1305 in Advanced/Metastatic Solid Tumors

RecruitingPhase 2
  • USA11-0, Bethesda · 7 mi away
Ages 18 and older · All sexes · Updated May 22, 2026 · NCT06953089

Cancer Experience Registry (CER) for Cancer Patients and Caregivers

RecruitingObservational studyHealthy volunteers welcome
  • Cancer Support Community Research & Training Institute, Washington D.C.
Ages 18 and older · All sexes · Updated Apr 23, 2026 · NCT02333604

A Randomized, Phase 2/3 Study to Investigate the Efficacy and Safety of RP2 in Combination With Nivolumab in Immune Checkpoint Inhibitor-Naïve Adult Patients With Metastatic Uveal Melanoma

RecruitingPhase 2/3
  • Georgetown University Medical Center, Washington D.C.
All ages · All sexes · Updated Apr 2, 2026 · NCT06581406

SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

RecruitingObservational study
  • Massive Bio SYNERGY-AI site, Silver Spring · 7 mi away
  • Massive Bio SYNERGY-AI site, Bethesda · 7 mi away
All ages · All sexes · Updated Oct 28, 2025 · NCT03452774

Melanoma Margins Trial-II: 1cm v 2cm Wide Surgical Excision Margins for AJCC Stage II Primary Cutaneous Melanoma

Recruiting
  • MedStar Georgetown University Hospital, Washington D.C.
  • MedStar Washington Hospital Center, Washington D.C.
Ages 18 and older · All sexes · Updated Nov 27, 2024 · NCT03860883

About Melanoma

Melanoma is the most serious type of skin cancer. Most have a black or black-blue area. Learn the 'ABCDE' of what to watch for and treatment options.

More about Melanoma on MedlinePlus

Melanoma trials in other cities

Other studies in Washington

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.