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Healthy volunteer studies in Orlando, FL

69 studies at sites in and around Orlando accept healthy volunteers — people without the condition being studied. Many studies pay participants for their time and travel; the amount is set by each study, so ask the study team.

Testing an Enhanced Digital Delivery Model for Inherited Cancer Genetic Testing in Young Adults With Cancer

RecruitingHealthy volunteers welcome
  • Arnold Palmer Hospital for Children, Orlando
  • Nemours Children's Hospital, Orlando
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT07091617

A Study to Evaluate the Pharmacokinetics and Safety of Golcadomide in Participants With Severe Renal Impairment and End-Stage Renal Disease Compared With Participants With Normal Renal Function

RecruitingPhase 1Healthy volunteers welcome
  • Orlando Clinical Research Center OCRC, Orlando
Ages 18 to 84 · All sexes · Updated Oct 1, 2026 · NCT07763418

A Study to Evaluate the Impact of Renal Impairment on the Pharmacokinetics (PK) of Ribupatide

RecruitingPhase 1Healthy volunteers welcome
  • Kailera Clinical Site, Orlando
Ages 18 to 85 · All sexes · Updated Oct 1, 2026 · NCT07793929

Study of XmAb942 in Healthy Participants and Participants With Ulcerative Colitis

RecruitingPhase 1/2Healthy volunteers welcome
  • Xencor Investigative Site, Kissimmee · 16 mi away
Ages 18 to 75 · All sexes · Updated Sep 29, 2026 · NCT06619990

Phase 1/2 Study of Respiratory Syncytial Virus and Human Metapneumovirus (RSV+HMPV) Vaccine Candidate in Adults 60 Years of Age and Older

RecruitingPhase 1/2Healthy volunteers welcome
  • Accel Research Sites - Maitland Clinical Research Unit- Site Number : 8400074, Maitland · 6 mi away
Ages 60 and older · All sexes · Updated Sep 24, 2026 · NCT07734649

Anchoring and Postural Stability

RecruitingHealthy volunteers welcome
  • University of Central Florida Spine and Mobility Lab, Orlando
Ages 18 to 50 · All sexes · Updated Sep 24, 2026 · NCT07837778

Effect of Hepatic Impairment on the Pharmacokinetics of Mirdametinib

RecruitingPhase 1Healthy volunteers welcome
  • Orlando Clinical Research Center, Orlando
Ages 18 to 80 · All sexes · Updated Sep 21, 2026 · NCT06997276

Cessation or Reduction of Alcohol Consumption in Veterans: A Randomized Controlled Trial for Alcohol Use Disorder (CRAVE)

RecruitingPhase 3Healthy volunteers welcome
  • Orlando VA Healthcare System, Orlando, FL, Orlando
Ages 18 to 80 · All sexes · Updated Sep 21, 2026 · NCT07218354

A Study on the Efficacy of a Vaccine Against Influenza in Adults ≥65 Years of Age

RecruitingPhase 3Healthy volunteers welcome
  • GSK Investigational Site, Orlando
  • GSK Investigational Site, Orlando
  • GSK Investigational Site, Maitland · 6 mi away
  • and 1 more
Ages 65 and older · All sexes · Updated Sep 18, 2026 · NCT07805707

A Study to Evaluate the Effect of Moderate or Severe Hepatic Impairment on the Pharmacokinetics (PK) of Inavolisib

RecruitingPhase 1Healthy volunteers welcome
  • Orlando Clinical Research Center, Orlando
Ages 18 to 80 · All sexes · Updated Sep 18, 2026 · NCT07144111

A Study to Assess the Adverse Events and How Oral Emraclidine Moves Through the Body of Healthy Elderly Adult Participants

RecruitingPhase 1Healthy volunteers welcome
  • K2 Medical Research, LLC /ID# 276636, Maitland · 6 mi away
Ages 65 to 85 · All sexes · Updated Sep 15, 2026 · NCT07219030

The Effects of Pacifier-Activated Lullaby on Oral Feeding Among Preterm Infants

RecruitingHealthy volunteers welcome
  • Nemours Children's Hospital, Florida, Orlando
34 Weeks – 36 Weeks · All sexes · Updated Sep 15, 2026 · NCT07819734

A Study of Aleniglipron in Adults With Obesity or Overweight and Type 2 Diabetes Mellitus (ACCOMPLISH-2)

RecruitingPhase 3Healthy volunteers welcome
  • ACCOMPLISH-2 Research Site, Ocoee · 10 mi away
Ages 18 to 79 · All sexes · Updated Sep 11, 2026 · NCT07654374

Quality of End-of-Life Care for Children With Cancer

RecruitingObservational studyHealthy volunteers welcome
  • Nemours Children's Hospital, Orlando
Ages 18 and older · All sexes · Updated Sep 4, 2026 · NCT07412002

A Study to Test How BI 1291583 is Taken up in the Blood of People With and Without Liver Problems

RecruitingPhase 1Healthy volunteers welcome
  • Orlando Clinical Research Center, Orlando
Ages 18 to 80 · All sexes · Updated Sep 4, 2026 · NCT07023354

A Study to Learn How the Study Medicine Called Atirmociclib is Handled by the Body in People With Normal Liver Function and Different Levels of Liver Disease

RecruitingPhase 1Healthy volunteers welcome
  • Orlando Clinical Research Center, Orlando
Ages 18 and older · All sexes · Updated Aug 21, 2026 · NCT07677358

A Study to Evaluate AZD7760 Safety and Pharmacokinetics in Healthy Adults (Phase I) and Adults With End-stage Kidney Disease on Hemodialysis With a Central Venous Catheter (Phase IIa)

RecruitingPhase 1/2Healthy volunteers welcome
  • Research Site, Orlando
Ages 18 to 55 · All sexes · Updated Aug 14, 2026 · NCT06749457

Does Style Matter: Comparison of Moderate- to Low-intensity Styles of Yoga

RecruitingHealthy volunteers welcome
  • University of Central Florida, Orlando
Ages 18 to 40 · All sexes · Updated Aug 13, 2026 · NCT07638267

Determining Cell- and Spatially-distinct Skeletal Muscle Transcriptional Aberrations in Insulin Resistance

RecruitingObservational studyHealthy volunteers welcome
  • AdventHealth Translational Research Institute, Orlando
Ages 30 to 65 · All sexes · Updated Aug 12, 2026 · NCT07516509

Acute Exercise and Endogenous Glucose Production in Type 2 Diabetes: Implications for Glycemic Control and Treatment of Hepatic Steatosis

RecruitingHealthy volunteers welcome
  • AdventHealth Translational Research Institute, Orlando
Ages 25 to 55 · All sexes · Updated Aug 12, 2026 · NCT06993454

Pneumococcal Carriage Duration

RecruitingObservational studyHealthy volunteers welcome
  • University of Central Florida, Orlando
28 Days – 48 Months · All sexes · Updated Aug 6, 2026 · NCT07748832

A Study to Learn How the Body Processes the Study Medicine PF-07328948 in People With and Without Reduced Liver Function

RecruitingPhase 1Healthy volunteers welcome
  • Orlando Clinical Research Center, Orlando
Ages 18 to 74 · All sexes · Updated Jul 23, 2026 · NCT07269301

A Study to Learn About the Treatment LTP001 in Healthy Participants (Part A) and in Participants With PAH (Part B)

RecruitingPhase 1/2Healthy volunteers welcome
  • Central Florida Pulmonary Group, Orlando
Ages 18 to 100 · All sexes · Updated Jul 21, 2026 · NCT06649110

BoxX-NoAF Clinical Trial

RecruitingHealthy volunteers welcome
  • Orlando Health, Inc., Orlando
Ages 65 and older · All sexes · Updated Jun 29, 2026 · NCT06989775

Increasing Germline Genetic Testing for Patients With Cancer

RecruitingHealthy volunteers welcome
  • Orlando VA Medical Center, Orlando
All ages · All sexes · Updated Jun 9, 2026 · NCT07307664

Pharmacokinetic Study of Vorasidenib in Severe Hepatically Impaired and Matched-Control Participants

RecruitingPhase 1Healthy volunteers welcome
  • Orlando Clinical Research Center, Orlando
Ages 18 to 75 · All sexes · Updated Jun 5, 2026 · NCT07250633

A Study of Eloralintide (LY3841136) in Participants With Different Levels of Liver Damage and in Participants With Healthy Livers.

RecruitingPhase 1Healthy volunteers welcome
  • Orlando Clinical Research Center, Orlando
Ages 18 to 85 · All sexes · Updated Jun 4, 2026 · NCT07401862

A Study of LY4006895 in Healthy Participants With Early Symptomatic Alzheimer's Disease (AD)

RecruitingPhase 1Healthy volunteers welcome
  • K2 Medical Research, Maitland · 6 mi away
Ages 45 to 85 · All sexes · Updated Jun 4, 2026 · NCT06657768

A Study to Determine the Effects of ENDS Flavor Availability on Abstinence Within Smokers

RecruitingHealthy volunteers welcome
  • Sago Orlando, Maitland · 6 mi away
Ages 21 to 65 · All sexes · Updated Jun 3, 2026 · NCT07598136

A Phase 1/2a Study of DB-2304 in Healthy Adults and SLE/CLE Participants

RecruitingPhase 1/2Healthy volunteers welcome
  • US05-0, Orlando
Ages 18 to 70 · All sexes · Updated Jun 2, 2026 · NCT06625671

Role of Body Composition in Large for Gestational Age Infants (LGA) With Oral Feeding Difficulty

RecruitingHealthy volunteers welcome
  • Nemours Children's Hospital, Orlando
1 Week – 10 Weeks · All sexes · Updated May 27, 2026 · NCT04599010

A Study to Learn How the Body Processes the Study Medicine PF-07328948 in People With Reduced Kidney Function

RecruitingPhase 1Healthy volunteers welcome
  • Orlando Clinical Research Center, Orlando
Ages 18 to 80 · All sexes · Updated May 12, 2026 · NCT07315360

Quadriceps Motor Unit Adaptation to Simulated Knee Injury

RecruitingEarly phase 1Healthy volunteers welcome
  • University of Central Florida, Orlando
Ages 18 to 30 · All sexes · Updated May 1, 2026 · NCT06999057

A Study to Learn About the Medicine Called PF-08653944 in People With and Without Reduced Liver Function

RecruitingPhase 1Healthy volunteers welcome
  • Orlando Clinical Research Center, Orlando
Ages 18 to 74 · All sexes · Updated Apr 23, 2026 · NCT07519135

A Study of LY4006896 in Healthy Participants and Participants With Parkinson's Disease

RecruitingPhase 1Healthy volunteers welcome
  • Charter Research, Orlando
Ages 30 to 85 · All sexes · Updated Apr 20, 2026 · NCT06809400

Development of a Database to Investigate Digital and Blood-Based Biomarkers and Their Relationship to Tau and Amyloid PET Imaging in Older Participants Who Are Cognitively Normal (CN), Have Mild Cognitive Impairment (MCI), or Have Mild-to-Moderate AD Dementia

RecruitingObservational studyHealthy volunteers welcome
  • Charter Research, Orlando
  • Conquest Research, Winter Park · 5 mi away
  • K2 Medical Research, Maitland · 6 mi away
  • and 1 more
Ages 60 to 90 · All sexes · Updated Apr 15, 2026 · NCT06584357

A Study to Learn How the Body Processes the Study Medicine Called Vepdegestrant in People With Loss of Liver Function

RecruitingPhase 1Healthy volunteers welcome
  • Orlando Clinical Research Center, Orlando
Ages 18 to 70 · All sexes · Updated Apr 3, 2026 · NCT07231991

Development and Validation of Multi-nuclear Magnetic Resonance Imaging and Spectroscopy for Whole Body Human Applications

RecruitingObservational studyHealthy volunteers welcome
  • Translational Research Institute for Metabolism and Diabetes, Orlando
Ages 12 to 89 · All sexes · Updated Mar 30, 2026 · NCT02663362

Assessments of Adipogenesis, Lipid Turnover and Cellular Composition in Adipose Tissue in Response to Endurance Exercise

RecruitingHealthy volunteers welcome
  • AdventHealth Translational Research Institute, Orlando
Ages 18 to 45 · All sexes · Updated Mar 27, 2026 · NCT06602141

Regeneration of Acutely Injured Nerves With Temporary Electrical Stimulation

RecruitingHealthy volunteers welcome
  • Orlando Health Jewett Orthopedic Institute, Orlando
Ages 18 to 65 · All sexes · Updated Mar 16, 2026 · NCT05721261

Study to Evaluate if Exposure to Drug is Impacted in Participants With Renal Insufficiency

RecruitingPhase 1Healthy volunteers welcome
  • Orlando Clinical Research Center (OCRC), Orlando
Ages 18 to 80 · All sexes · Updated Mar 13, 2026 · NCT07385547

Beat Childhood Cancer Specimen Banking and Data Registry

RecruitingObservational studyHealthy volunteers welcome
  • Arnold Palmer Hospital for Children, Orlando
All ages · All sexes · Updated Feb 3, 2026 · NCT04715178

The Utilization of Ultrasound to Diagnose Pediatric Elbow Fractures

RecruitingHealthy volunteers welcome
  • Nemours Children's Hospital, Orlando
Up to age 18 · All sexes · Updated Jan 29, 2026 · NCT07212036

Caris Biorepository Research Protocol

RecruitingObservational studyHealthy volunteers welcome
  • Advent Health, Orlando
Ages 18 and older · All sexes · Updated Jan 21, 2026 · NCT01499394

Efficacy in Controlling Myopia in Young Children Using a Novel Spectacle Lens

RecruitingHealthy volunteers welcome
  • Omega Vision Center, Longwood · 12 mi away
Ages 6 to 8 · All sexes · Updated Dec 29, 2025 · NCT06034327

Clofutriben Pharmacokinetics in Patients With Impaired Renal Function

RecruitingPhase 1Healthy volunteers welcome
  • Orlando Clinical Research Center, Orlando
Ages 18 to 83 · All sexes · Updated Dec 23, 2025 · NCT07227922

Building on Trust: Navigating Preventive Lung, Breast, and Prostate Cancer Screenings at Community Resource Spots

RecruitingObservational studyHealthy volunteers welcome
  • Adventhealth, Orlando
Ages 18 and older · All sexes · Updated Nov 17, 2025 · NCT07231159

An Evaluation of an Online Sexual Assault Resistance Program (IDEA3)

RecruitingHealthy volunteers welcome
  • University of Central Florida, Orlando
Ages 17 to 24 · All sexes · Updated Oct 21, 2025 · NCT06058455

UCF MammoChat: Image Repository

RecruitingObservational studyHealthy volunteers welcome
  • University of Central Florida, Orlando
Ages 18 and older · All sexes · Updated Oct 9, 2025 · NCT07214883

Natural History Evaluation of Charcot Marie Tooth Disease (CMT) Types CMT1B, CMT2A, CMT4A, CMT4C, and Others

RecruitingObservational studyHealthy volunteers welcome
  • Nemours Children's Health, Orlando
  • Nemours Children's Hospital, Orlando
All ages · All sexes · Updated Oct 7, 2025 · NCT01193075

Pharmacokinetics (PK) and Safety of Zanzalintinib in Participants With Moderate Hepatic Impairment (HI)

RecruitingPhase 1Healthy volunteers welcome
  • Exelixis Clinical Site #1, Orlando
Ages 18 to 75 · All sexes · Updated Jun 22, 2025 · NCT06962332

Gut Microbiomes in HD

RecruitingObservational studyHealthy volunteers welcome
  • University of Central Florida, Orlando
Ages 18 and older · All sexes · Updated Jun 18, 2025 · NCT06448546

UCF Deciding Brains

RecruitingObservational studyHealthy volunteers welcome
  • University of Central Florida, Orlando
Ages 20 and older · All sexes · Updated Mar 27, 2025 · NCT06176092

University of Central Florida BEEAST

RecruitingObservational studyHealthy volunteers welcome
  • University of Central Florida, Orlando
Ages 18 and older · All sexes · Updated Mar 26, 2025 · NCT06781424

University of Central Florida CereBank

RecruitingObservational studyHealthy volunteers welcome
  • University of Central Florida, Orlando
Ages 18 and older · Women · Updated Mar 14, 2025 · NCT06876857

The Role of Type 2 Diabetes on Skeletal Muscle Atrophy and Recovery Following Bed Rest in Older Adults

RecruitingHealthy volunteers welcome
  • Translational Research Institute for Metabolism and Diabetes, Orlando
Ages 60 to 80 · All sexes · Updated Mar 13, 2025 · NCT03761446

AdventHealth Research Institute Non-Alcoholic Fatty Liver Disease Biobank and Registry (AVAIL)

RecruitingObservational studyHealthy volunteers welcome
  • AdventHealth Translational Research Institute, Orlando
Ages 18 and older · All sexes · Updated Mar 13, 2025 · NCT04807868

Unity Cures Future (UCF) Biobank

RecruitingObservational studyHealthy volunteers welcome
  • University of Central Florida, Orlando
Ages 18 and older · All sexes · Updated Jan 17, 2025 · NCT06781411

Effect of Resveratrol Supplementation on Exercise Performance and Recovery

RecruitingHealthy volunteers welcome
  • University of Central Florida EPIC Lab, Orlando
Ages 18 to 40 · Men · Updated Dec 9, 2024 · NCT06723119

Blood Collection for COM/BSBS

RecruitingObservational studyHealthy volunteers welcome
  • University of Central Florida, Orlando
Ages 18 and older · All sexes · Updated Dec 6, 2024 · NCT06082661

The Lake Nona Life Project

RecruitingObservational studyHealthy volunteers welcome
  • Lake Nona Institute, Orlando
Ages 18 to 110 · All sexes · Updated Dec 6, 2024 · NCT02533804

De-identified Human Tissue Project

RecruitingObservational studyHealthy volunteers welcome
  • University of Central Florida, Orlando
Ages 18 and older · All sexes · Updated Dec 6, 2024 · NCT06082687

Contact Registry for Clinical Trials

RecruitingObservational studyHealthy volunteers welcome
  • University of Central Florida, Orlando
Ages 18 and older · All sexes · Updated Dec 6, 2024 · NCT06084312

HIV Prevention Intervention for Latino Male Couples

RecruitingHealthy volunteers welcome
  • University of Central Florida, Orlando
Ages 18 to 100 · Men · Updated Dec 6, 2024 · NCT06131931

Post Pandemic Pneumococcal Carriage Among Children and Adults

RecruitingObservational studyHealthy volunteers welcome
  • University of Central Florida, Orlando
7 Months · All sexes · Updated Dec 6, 2024 · NCT06373328

Extracellular Vesicles for HD

RecruitingObservational studyHealthy volunteers welcome
  • University of Central Florida, Orlando
Ages 18 to 75 · All sexes · Updated Dec 6, 2024 · NCT06082713

Innate Immunity in Allergic Asthma

RecruitingObservational studyHealthy volunteers welcome
  • University of Central Florida, Orlando
Ages 18 and older · All sexes · Updated Dec 6, 2024 · NCT06068335

PyloPlus Urea Breath Test System Pediatric Safety and Efficacy Study

RecruitingPhase 3Healthy volunteers welcome
  • Orlando Health, Inc., Orlando
Ages 3 to 17 · All sexes · Updated May 6, 2023 · NCT05276557

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.