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Breast Cancer clinical trials in Saint Paul, MN

12 studies for Breast Cancer are looking for participants at sites in and around Saint Paul (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection

RecruitingObservational studyHealthy volunteers welcome
  • Regions Hospital, Saint Paul
  • United Hospital, Saint Paul
  • Minnesota Oncology Hematology PA-Maplewood, Maplewood · 5 mi away
  • and 3 more
Ages 40 to 75 · All sexes · Updated Oct 2, 2026 · NCT05334069

A Study of HER3-DXd in Subjects With Locally Advanced or Metastatic Solid Tumors

RecruitingPhase 2
  • Health Partners Cancer Center at Regions Hospital, Saint Paul
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT06172478

ROSETTA Breast-01: The Effects and Safety of Pumitamig in Patients With Triple-Negative Breast Cancer

RecruitingPhase 3
  • Healthpartners Regions Specialty Clinics, Saint Paul
Ages 18 and older · All sexes · Updated Sep 17, 2026 · NCT07173751

A Study Evaluating the Efficacy and Safety of Multiple Treatment Combinations in Patients With Metastatic or Locally Advanced Breast Cancer

RecruitingPhase 1/2
  • Metro-Minnesota Community Oncology Research Consortium, Saint Paul
Ages 18 and older · All sexes · Updated Sep 10, 2026 · NCT03424005

Evaluating the Addition of Adjuvant Chemotherapy to Ovarian Function Suppression Plus Endocrine Therapy in Premenopausal Patients With pN0-1, ER-Positive/HER2-Negative Breast Cancer and an Oncotype Recurrence Score Less Than or Equal to 25

RecruitingPhase 3
  • Regions Hospital, Saint Paul
  • United Hospital, Saint Paul
  • Minnesota Oncology Hematology PA-Maplewood, Maplewood · 5 mi away
  • and 3 more
Ages 18 to 60 · Women · Updated Sep 2, 2026 · NCT05879926

Rinatabart Sesutecan (Rina-S, PRO1184, GEN1184) for Advanced Solid Tumors (GCT1184-01/ PRO1184-001)

RecruitingPhase 1/2
  • USOR Minnesota Oncology Hematology, Maplewood · 5 mi away
Ages 18 and older · All sexes · Updated Aug 4, 2026 · NCT05579366

A Study to Learn About the Study Medicine Called PF-07248144 in Combination With Fulvestrant in People With HR-positive, HER2-negative Advanced or Metastatic Breast Cancer Who Progressed After a Prior Line of Treatment.

RecruitingPhase 3
  • Minnesota Oncology Hematology, P.A., Maplewood · 5 mi away
  • Minnesota Oncology Hematology, P.A., Woodbury · 7 mi away
Ages 18 and older · All sexes · Updated May 6, 2026 · NCT07062965

Axelopran for Advanced Cancer in Patients Receiving Opioids

RecruitingPhase 2
  • HealthPartners Cancer Center at Regions Hospital, Saint Paul
Ages 18 and older · All sexes · Updated May 5, 2026 · NCT07354919

De-Escalation of Breast Radiation Trial for Hormone Sensitive, HER-2 Negative, Oncotype Recurrence Score Less Than or Equal to 18 Breast Cancer (DEBRA)

RecruitingPhase 3
  • Regions Hospital, Saint Paul
  • United Hospital, Saint Paul
  • Minnesota Oncology Hematology PA-Maplewood, Maplewood · 5 mi away
  • and 2 more
Ages 50 to 70 · All sexes · Updated Apr 23, 2026 · NCT04852887

Assessing Benefits and Harms of Cannabis/Cannabinoid Use Among Cancer Patients Treated in Community Oncology Clinics

RecruitingObservational study
  • Regions Hospital, Saint Paul
  • United Hospital, Saint Paul
  • Minnesota Oncology Hematology PA-Maplewood, Maplewood · 5 mi away
  • and 3 more
Ages 18 and older · All sexes · Updated Mar 17, 2026 · NCT06418204

S1501 Dual Observational and Randomized Cohort Study of Patients With Metastatic HER-2+ Breast Cancer at Risk of Cardiac Toxicity

RecruitingPhase 3
  • Regions Hospital, Saint Paul
  • United Hospital, Saint Paul
  • Minnesota Oncology Hematology PA-Maplewood, Maplewood · 5 mi away
  • and 1 more
Ages 18 and older · All sexes · Updated Oct 8, 2025 · NCT03418961

About Breast Cancer

Breast cancer is a cancer that starts in the breast tissue, when cells change and grow out of control. These extra cells can form a mass called a tumor.

More about Breast Cancer on MedlinePlus

Breast Cancer trials in other cities

Other studies in Saint Paul

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.