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Melanoma clinical trials in Oklahoma City, OK

10 studies for Melanoma are looking for participants at sites in and around Oklahoma City (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection

RecruitingObservational studyHealthy volunteers welcome
  • Mercy Hospital Oklahoma City, Oklahoma City
Ages 40 to 75 · All sexes · Updated Oct 2, 2026 · NCT05334069

BiCaZO: A Study Combining Two Immunotherapies (Cabozantinib and Nivolumab) to Treat Patients With Advanced Melanoma or Squamous Cell Head and Neck Cancer, an immunoMATCH Pilot Study

RecruitingPhase 2
  • University of Oklahoma Health Sciences Center, Oklahoma City
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT05136196

Comparing the Effectiveness of Less Invasive Procedures With the Current Standard of Care for the Treatment of Older Adults With Early-Stage Melanoma

RecruitingPhase 3
  • University of Oklahoma Health Sciences Center, Oklahoma City
Ages 75 and older · All sexes · Updated Sep 24, 2026 · NCT07068074

A Study to Compare the Administration of Encorafenib + Binimetinib + Nivolumab Versus Ipilimumab + Nivolumab in BRAF-V600 Mutant Melanoma With Brain Metastases

RecruitingPhase 2
  • University of Oklahoma Health Sciences Center, Oklahoma City
  • Mercy Hospital Oklahoma City, Oklahoma City
Ages 18 and older · All sexes · Updated Sep 15, 2026 · NCT04511013

Project: Every Child for Younger Patients With Cancer

RecruitingObservational study
  • University of Oklahoma Health Sciences Center, Oklahoma City
Up to age 25 · All sexes · Updated Aug 25, 2026 · NCT02402244

Predicting Response to Immunotherapy From Analysis of Live Tumor Biopsies (ELEPHAS-05)

RecruitingObservational study
  • Mercy Hospital - OKC, Oklahoma City
Ages 18 and older · All sexes · Updated Jun 29, 2026 · NCT07327489

Neoadjuvant Darovasertib in Primary Uveal Melanoma

RecruitingPhase 3
  • Retina Consultants of Oklahoma, Oklahoma City
Ages 18 and older · All sexes · Updated May 6, 2026 · NCT07015190

Assessing Benefits and Harms of Cannabis/Cannabinoid Use Among Cancer Patients Treated in Community Oncology Clinics

RecruitingObservational study
  • Mercy Hospital Oklahoma City, Oklahoma City
Ages 18 and older · All sexes · Updated Mar 17, 2026 · NCT06418204

Tebentafusp Regimen Versus Investigator's Choice in Previously Treated Advanced Melanoma (TEBE-AM)

RecruitingPhase 3
  • OU Health Stephenson Cancer Center, Oklahoma City
Ages 18 and older · All sexes · Updated Feb 25, 2026 · NCT05549297

Melanoma Margins Trial-II: 1cm v 2cm Wide Surgical Excision Margins for AJCC Stage II Primary Cutaneous Melanoma

Recruiting
  • OUHSC Stephenson Cancer Center, Oklahoma City
  • Mercy Health Center - Oncology Hematology, Oklahoma City
Ages 18 and older · All sexes · Updated Nov 27, 2024 · NCT03860883

About Melanoma

Melanoma is the most serious type of skin cancer. Most have a black or black-blue area. Learn the 'ABCDE' of what to watch for and treatment options.

More about Melanoma on MedlinePlus

Melanoma trials in other cities

Other studies in Oklahoma City

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.