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Cognitive-Behavioral Therapy and Exercise Training in Adolescents At-Risk for Type 2 Diabetes
Who can join
Ages 12 to 17 · Women · Healthy volunteers welcome
Full eligibility criteria
Inclusion Criteria: * Female * Age 12-17 years * Body Mass Index (BMI)\>= 85 for age and sex * Type 2 Diabetes (T2D) first-or second-degree relative * Center for Epidemiologic Studies Depression Scale (CES-D) total score \>=21 Exclusion Criteria: * T2D/ Type 1 Diabetes (T1D) or any major medical condition (e.g. cardiovascular, renal) that would prohibit the ability to participate in exercise training * Diagnostic and Statistical Manual of Mental Disorders, 5th Edition (DSM-5) conduct disorder, substance abuse/ dependence, obsessive compulsive disorder, panic attacks, post-traumatic stress disorder, anorexia/bulimia, \& schizophrenia * Insulin sensitizers, weight loss medications \& chronic steroids * Structured weight loss treatment or bariatric surgery * Pregnancy, nursing
About the study
The investigators are doing this study to learn more about how to prevent type 2 diabetes in teenage girls. The purpose of this study is to find out if taking part in a cognitive-behavioral therapy group, exercise training group, or a combination of cognitive-behavioral therapy and exercise training groups, decreases stress, improves mood, increases physical activity and physical fitness, and decreases insulin resistance among teenagers at risk for diabetes.
What is being tested
- Cognitive-Behavioral Therapy followed by Exercise Training (behavioral)
- Exercise Training followed by Cognitive-Behavioral Therapy (behavioral)
- Cognitive-Behavioral Therapy Only (behavioral)
- Exercise Training Only (behavioral)
Sponsor: Colorado State University · Participants: 300 · Started: Jun 2, 2023
Contact the study team
- Lauren B Shomaker, PhD · Phone: 970-491-3217
- Madison Bristol · Phone: 720-777-6128
Official record on ClinicalTrials.gov — NCT05543083
Locations in the U.S.
| Colorado | Children's Hospital Colorado, Aurora Colorado State University, Fort Collins |
Conditions
From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.