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Human Observatory Study

The Human Observatory: A Prospective Individual and Population-Level Study of Aging, Health, and Longevity

Who can join

Ages 18 and older · All sexes · Healthy volunteers welcome

Inclusion Criteria:

* Enrolled in the 100-Year Human Aging Study at any fixed or mobile clinical site; OR completion of online health screener with provision of geographic anchor data and consent.

Exclusion Criteria:

* Age under 18 years (current protocol; pediatric amendment planned).

About the study

The Human Observatory Study is a prospective observational and ecological surveillance study building a continuously-updating world model for human health, disease, and death at the individual and population level. Individual multi-system clinical data from enrolled participants are linked to a continuously-ingested ecological data infrastructure spanning environmental exposures, social determinants, genealogical and family history records, mortality data, and population health databases at geographic resolutions from home address to global scale and beyond. The resulting model generates individual screening recommendations informed by population-level causal estimates, and population-level causal forecasts anchored by present-timepoint individual clinical biology. This linkage creates a feedback architecture designed to improve both simultaneously.

What is being tested

• Multi-Domain Ecological and Clinical Data Linkage (other)

Sponsor: Longevity Metrics, Inc. · Participants: 1,000,000 · Started: Apr 25, 2026

Contact the study team

• William Brandenburg, MD · Phone: 13035010016

Official record on ClinicalTrials.gov — NCT07646782

Locations in the U.S.

Conditions

• Cardiovascular Disease
• Cancer (all types)
• Mild Cognitive Impairment
• Metabolic Syndrome
• Frailty
• Degenerative Nerve Diseases
• Dementia
• Occupational Health

From ClinicalTrials.gov, data retrieved Sep 29, 2026. Each study sets its own eligibility; the study team decides who can join.