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Breast Cancer clinical trials in Milwaukee, WI

23 studies for Breast Cancer are looking for participants at sites in and around Milwaukee (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

The Vanguard Study: Testing a New Way to Screen for Cancer

RecruitingHealthy volunteers welcome
  • Zablocki Veterans Administration Medical Center, Milwaukee
Ages 45 to 75 · All sexes · Updated Oct 5, 2026 · NCT06995898

Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection

RecruitingObservational studyHealthy volunteers welcome
  • Aurora Cancer Care-Milwaukee, Milwaukee
  • Aurora Saint Luke's Medical Center, Milwaukee
  • Aurora Sinai Medical Center, Milwaukee
  • and 9 more
Ages 40 to 75 · All sexes · Updated Oct 2, 2026 · NCT05334069

A Study of NT-175 in Adult Participants With Advanced Malignancies That Are Positive for HLA-A*02:01 and the TP53 R175H Mutation

RecruitingPhase 1
  • Research Site, Milwaukee
Ages 18 and older · All sexes · Updated Sep 29, 2026 · NCT05877599

Palazestrant in Combination With Ribociclib for the First-line Treatment of ER+/HER2- Advanced Breast Cancer

RecruitingPhase 3
  • Clinical Trial Site, Milwaukee
Ages 18 and older · All sexes · Updated Sep 23, 2026 · NCT07085767

ROSETTA Breast-01: The Effects and Safety of Pumitamig in Patients With Triple-Negative Breast Cancer

RecruitingPhase 3
  • Medical College of Wisconsin, Milwaukee
Ages 18 and older · All sexes · Updated Sep 17, 2026 · NCT07173751

A Phase 1/2 Trial of TER-2013 in Patients With Solid Tumors Harboring AKT/PI3K/PTEN Pathway Alterations

RecruitingPhase 1/2
  • Froedtert & MCW Cancer Center, Milwaukee
Ages 18 and older · All sexes · Updated Sep 17, 2026 · NCT07109726

A Study of Elacestrant Versus Standard Endocrine Therapy in Women and Men With ER+,HER2-, Early Breast Cancer With High Risk of Recurrence

RecruitingPhase 3
  • Froedtert Hospital & the Medical College of Wisconsin, Milwaukee
Ages 18 and older · All sexes · Updated Sep 15, 2026 · NCT06492616

Evaluating the Addition of Adjuvant Chemotherapy to Ovarian Function Suppression Plus Endocrine Therapy in Premenopausal Patients With pN0-1, ER-Positive/HER2-Negative Breast Cancer and an Oncotype Recurrence Score Less Than or Equal to 25

RecruitingPhase 3
  • Aurora Cancer Care-Milwaukee, Milwaukee
  • Aurora Saint Luke's Medical Center, Milwaukee
  • Medical College of Wisconsin, Milwaukee
  • and 8 more
Ages 18 to 60 · Women · Updated Sep 2, 2026 · NCT05879926

Safety, PK and Efficacy of QXL138AM in Patients With Solid Tumors and Multiple Myeloma

RecruitingPhase 1
  • Froedtert Hospital & the Medical College of Wisconsin, Milwaukee
Ages 18 and older · All sexes · Updated Aug 27, 2026 · NCT06582017

Dosing Physical Activity Among Older Cancer Survivors Who Experience Chronic Pain: a Micro-randomized Trial

Recruiting
  • Froedtert Hospital, Milwaukee
Ages 65 and older · All sexes · Updated Aug 20, 2026 · NCT07227077

Impact of Intermittent Fasting on Biomarkers of Inflammation and Health-Related Quality of Life: A Feasibility Trial for Women With HR+/HER2- Early Breast Cancer

Recruiting
  • Froedtert Hospital & the Medical College of Wisconsin, Milwaukee
Ages 18 and older · All sexes · Updated Aug 5, 2026 · NCT06106477

E-Mindfulness Approaches for Living After Breast Cancer

RecruitingPhase 3
  • UW Cancer Center at ProHealth Care, Waukesha · 17 mi away
  • ProHealth D N Greenwald Center, Mukwonago · 25 mi away
Ages 18 to 50 · All sexes · Updated Aug 4, 2026 · NCT06748222

De-Escalation of Breast Radiation Trial for Hormone Sensitive, HER-2 Negative, Oncotype Recurrence Score Less Than or Equal to 18 Breast Cancer (DEBRA)

RecruitingPhase 3
  • Aurora Cancer Care-Milwaukee, Milwaukee
  • Aurora Saint Luke's Medical Center, Milwaukee
  • Medical College of Wisconsin, Milwaukee
  • and 9 more
Ages 50 to 70 · All sexes · Updated Apr 23, 2026 · NCT04852887

Assessing Benefits and Harms of Cannabis/Cannabinoid Use Among Cancer Patients Treated in Community Oncology Clinics

RecruitingObservational study
  • Aurora Cancer Care-Milwaukee, Milwaukee
  • Ascension Columbia Saint Mary's Hospital - Milwaukee, Milwaukee
  • Aurora Saint Luke's Medical Center, Milwaukee
  • and 10 more
Ages 18 and older · All sexes · Updated Mar 17, 2026 · NCT06418204

The MOMENTUM Study: The Multiple Outcome Evaluation of Radiation Therapy Using the MR-Linac Study

RecruitingObservational study
  • Medical College of Wisconsin, Milwaukee
Ages 18 and older · All sexes · Updated Mar 5, 2026 · NCT04075305

Safety Study of MELK Inhibitor to Treat Patients With Advanced Breast Cancer and Triple Negative Breast Cancer

RecruitingPhase 1
  • Froedtert Hospital & the Medical College of Wisconsin, Milwaukee
Ages 18 and older · All sexes · Updated Feb 25, 2026 · NCT02926690

EXActDNA-003 / NSABP B-64: Study of Molecular Residual Disease Detection in Breast Cancer (MRD)

RecruitingObservational study
  • Aurora Cancer Care - Wauwatosa, Wauwatosa · 5 mi away
Ages 18 and older · All sexes · Updated Jan 20, 2026 · NCT06401421

SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

RecruitingObservational study
  • Massive Bio SYNERGY-AI site, Milwaukee
All ages · All sexes · Updated Oct 28, 2025 · NCT03452774

Molecular Analyses to Predict Pathways of Endocrine Resistance Following Short Term Neoadjuvant Endocrine Treatment in Patients With Hormone Receptor-Positive HER2-negative Breast Cancer

RecruitingPhase 2
  • Froedtert Hospital and the Medical College of Wisconsin, Milwaukee
Ages 18 and older · Women · Updated Oct 14, 2025 · NCT06361940

Individuals on Hormone Therapy Breast Cancer Screening Pilot

RecruitingObservational studyHealthy volunteers welcome
  • Medical College of Wisconsin, Milwaukee
Ages 30 to 75 · All sexes · Updated Sep 23, 2025 · NCT06383026

MammaPrint, BluePrint, and Full-genome Data Linked With Clinical Data to Evaluate New Gene EXpression Profiles

RecruitingObservational study
  • Columbia St. Mary's, Milwaukee
Ages 18 and older · All sexes · Updated Aug 20, 2025 · NCT03053193

Every Day Counts: A Lifestyle Program for Women With Metastatic Breast Cancer

Recruiting
  • Medical College of Wisconsin, Milwaukee
Ages 18 and older · Women · Updated Apr 27, 2025 · NCT03824145

About Breast Cancer

Breast cancer is a cancer that starts in the breast tissue, when cells change and grow out of control. These extra cells can form a mass called a tumor.

More about Breast Cancer on MedlinePlus

Breast Cancer trials in other cities

Other studies in Milwaukee

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.