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Glioma clinical trials recruiting in the U.S.

118 studies for Glioma are recruiting participants at sites across the United States.

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Recently updated studies

MCT for the Harvard/UCSF ROBIN Center

Recruiting
All ages ยท All sexes ยท Updated Oct 1, 2026 ยท NCT06000787

A Study of the Drug Selinexor With Radiation Therapy in Patients With Newly-Diagnosed Diffuse Intrinsic Pontine (DIPG) Glioma and High-Grade Glioma (HGG)

RecruitingPhase 1/2
12 Months โ€“ 21 Years ยท All sexes ยท Updated Oct 1, 2026 ยท NCT05099003

Preoperative Radiosurgery for the Treatment of High Grade Glioma, NeoGlioma Trial

RecruitingPhase 1
Ages 18 and older ยท All sexes ยท Updated Sep 30, 2026 ยท NCT05030298

Language Network Prehab Via fMRI Neurofeedback

Recruiting
Ages 18 and older ยท All sexes ยท Updated Sep 29, 2026 ยท NCT07488780

Study of Silevertinib With Temozolomide for the Treatment of Newly Diagnosed GBM With Unmethylated MGMT and EGFRvIII

RecruitingPhase 2
Ages 18 and older ยท All sexes ยท Updated Sep 28, 2026 ยท NCT07326566

Novel Indenoisoquinolone CMYC/TOPOISOMERASE 1 Inhibitor (LMP744) in Recurrent Glioblastoma

RecruitingPhase 1/2
Ages 18 to 99 ยท All sexes ยท Updated Sep 28, 2026 ยท NCT07416188

A Study of Repotrectinib in Pediatric and Young Adult Subjects Harboring ALK, ROS1, OR NTRK1-3 Alterations

RecruitingPhase 1/2
Up to age 25 ยท All sexes ยท Updated Sep 25, 2026 ยท NCT04094610

MSC-DNX-2401 in Treating Patients With Recurrent High-Grade Glioma

RecruitingPhase 1
Ages 18 and older ยท All sexes ยท Updated Sep 25, 2026 ยท NCT03896568

Evaluation of 18F-Fluciclovine Positron Emission Tomography - Magnetic Resonance Imaging (PET-MRI) in LGG

RecruitingEarly phase 1
Ages 1 to 21 ยท All sexes ยท Updated Sep 22, 2026 ยท NCT05555550

ACT001 for the Treatment of Diffuse Intrinsic Pontine Gliomas and H3K27-altered High Grade Gliomas

RecruitingPhase 2
12 Months โ€“ 39 Years ยท All sexes ยท Updated Sep 21, 2026 ยท NCT06838676

Trial of Anti-PD-1 Immunotherapy and Stereotactic Radiation in Patients With Recurrent Glioblastoma

RecruitingPhase 1/2
Ages 18 and older ยท All sexes ยท Updated Sep 21, 2026 ยท NCT04977375

Development of MRF for Characterization of Brain Tumors After Radiotherapy

RecruitingHealthy volunteers welcome
Ages 18 to 60 ยท All sexes ยท Updated Sep 15, 2026 ยท NCT06101069

A Study of the Safety, Dosing, and Delivery of NEO100 in Patients With Pediatric Brain Tumors

RecruitingPhase 1
Ages 5 to 18 ยท All sexes ยท Updated Sep 15, 2026 ยท NCT06357377

A Study of Temodar With Abexinostat (PCI-24781) for Patients With Recurrent Glioma

RecruitingPhase 1
Ages 19 and older ยท All sexes ยท Updated Sep 14, 2026 ยท NCT05698524

Serial Advanced Magnetic Resonance Imaging Scan for Guidance of Personalized Adaptive Radiotherapy for High Grade Glioma

RecruitingObservational study
Ages 18 and older ยท All sexes ยท Updated Sep 14, 2026 ยท NCT04771806

NgFUS NIVO: NeuroNavigation-Guided Focused Ultrasound With Nivolumab in Relapsed and Progressive DMG and Other High Grade Brain Tumors

RecruitingPhase 1
Ages 3 to 25 ยท All sexes ยท Updated Sep 9, 2026 ยท NCT07664176

Targeted Pediatric High-Grade Glioma Therapy

RecruitingObservational study
12 Months โ€“ 39 Years ยท All sexes ยท Updated Sep 8, 2026 ยท NCT05839379

HSV G207 in Children With Recurrent or Refractory Cerebellar Brain Tumors

RecruitingPhase 1
36 Months โ€“ 22 Years ยท All sexes ยท Updated Sep 4, 2026 ยท NCT03911388

A Study of Mirdametinib in People With Central Nervous System Tumors

RecruitingPhase 1/2
Ages 18 and older ยท All sexes ยท Updated Sep 3, 2026 ยท NCT07539441

Assessing Brain Metabolism Using MRS With Deuterated Glucose

RecruitingObservational studyHealthy volunteers welcome
Ages 18 and older ยท All sexes ยท Updated Sep 2, 2026 ยท NCT06594315

Study of Olutasidenib and Temozolomide in HGG

RecruitingPhase 2
Ages 12 to 39 ยท All sexes ยท Updated Sep 1, 2026 ยท NCT06161974

Glioma Developmental and HyperActive Ras Tumor (DHART) Board

RecruitingObservational study
Ages 18 and older ยท All sexes ยท Updated Aug 31, 2026 ยท NCT05489783

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.