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Glioma clinical trials in St. Louis, MO

10 studies for Glioma are looking for participants at sites in and around St. Louis (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

A Study of the Drug Selinexor With Radiation Therapy in Patients With Newly-Diagnosed Diffuse Intrinsic Pontine (DIPG) Glioma and High-Grade Glioma (HGG)

RecruitingPhase 1/2
  • Cardinal Glennon Children's Medical Center, St Louis
  • Washington University School of Medicine, St Louis
  • Mercy Hospital Saint Louis, St Louis
12 Months – 21 Years · All sexes · Updated Oct 1, 2026 · NCT05099003

Study of Silevertinib With Temozolomide for the Treatment of Newly Diagnosed GBM With Unmethylated MGMT and EGFRvIII

RecruitingPhase 2
  • Washington University School of Medicine Siteman Cancer Center, St Louis
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07326566

A Study of Repotrectinib in Pediatric and Young Adult Subjects Harboring ALK, ROS1, OR NTRK1-3 Alterations

RecruitingPhase 1/2
  • Washington University School of Medicine in St. Louis, St Louis
Up to age 25 · All sexes · Updated Sep 25, 2026 · NCT04094610

ACT001 for the Treatment of Diffuse Intrinsic Pontine Gliomas and H3K27-altered High Grade Gliomas

RecruitingPhase 2
  • St. Louis Children's Hospital, St Louis
12 Months – 39 Years · All sexes · Updated Sep 21, 2026 · NCT06838676

HSV G207 in Children With Recurrent or Refractory Cerebellar Brain Tumors

RecruitingPhase 1
  • Siteman Cancer Center at Washington University, St Louis
36 Months – 22 Years · All sexes · Updated Sep 4, 2026 · NCT03911388

SIGMA (Safusidenib in IDH1 Mutant Glioma Maintenance)

RecruitingPhase 3
  • Washington University, St Louis
Ages 18 and older · All sexes · Updated Aug 28, 2026 · NCT05303519

PEP-CMV Vaccine Targeting CMV Antigen to Treat Newly Diagnosed Pediatric HGG and DIPG and Recurrent Medulloblastoma

RecruitingPhase 2
  • St. Louis Children's Hospital, St Louis
Ages 3 to 39 · All sexes · Updated Aug 24, 2026 · NCT05096481

Trametinib and Everolimus for Treatment of Pediatric and Young Adult Patients With Recurrent Gliomas (PNOC021)

RecruitingPhase 1
  • Washington University in St. Louis, St Louis
Ages 1 to 25 · All sexes · Updated Aug 18, 2026 · NCT04485559

Window of Opportunity Study of DSP-0390 in Gliomas

RecruitingEarly phase 1
  • Washington University School of Medicine, St Louis
Ages 18 and older · All sexes · Updated May 6, 2026 · NCT06636162

Inflammation in Primary and Secondary Malignancies of the Central Nervous System Using [C-11]-CS1P1

RecruitingPhase 2
  • Washington University School of Medicine, St Louis
Ages 18 and older · All sexes · Updated Apr 21, 2026 · NCT07462507

Glioma trials in other cities

Other studies in St. Louis

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.