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Post-COVID Conditions (Long COVID) clinical trials in Boston, MA

13 studies for Post-COVID Conditions (Long COVID) are looking for participants at sites in and around Boston (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

A Safety and Immunogenicity Trial of OCU500, ChAd36 Vector Encoding SARS-CoV-2 Spike Vaccine Via Intranasal and Inhalational Routes in Previously Vaccinated Adults

RecruitingPhase 1Healthy volunteers welcome
  • Brigham and Women's Hospital, Boston
Ages 18 to 64 · All sexes · Updated Oct 2, 2026 · NCT07536308

A Study to Learn About the Study Medicine Ibuzatrelvir in Adults With COVID-19 Who Are Severely Immunocompromised

RecruitingPhase 3
  • Brigham and Women's Hospital, Boston
  • Clinical Trials Center, Boston
  • Clinical Trials Hub, Boston
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT07013474

Randomized Double-Blind Placebo-Controlled Trial EValuating Baricitinib on PERSistent NEurologic and Cardiopulmonary Symptoms of Long COVID

RecruitingPhase 3
  • Brigham and Women's Hospital, Boston
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06631287

A Study to Learn About a Study Medicine Called Ibuzatrelvir in Adult and Adolescent Patients With COVID-19 Who Are Not Hospitalized But Are at Risk For Severe Disease

RecruitingPhase 3
  • Brigham and Women's Hospital, Boston
Ages 12 and older · All sexes · Updated Sep 25, 2026 · NCT06679140

Defibrotide for the Treatment of Severe COVID-19

RecruitingPhase 2Healthy volunteers welcome
  • Brigham and Women's Hospital, Boston
Ages 18 to 100 · All sexes · Updated Jul 20, 2026 · NCT04652115

Kisspeptin to Quantify GnRH Neuronal Function in Health and Disease

RecruitingPhase 1
  • Massachusetts General Hospital, Boston
Ages 18 to 60 · All sexes · Updated Jul 13, 2026 · NCT07224490

Phase III DAS181 Lower Tract PIV Infection in Immunocompromised Subjects (Substudy: DAS181 for COVID-19): RCT Study

RecruitingPhase 3
  • Brigham and Women's Hospital, Boston
All ages · All sexes · Updated Jun 23, 2026 · NCT03808922

Positron Emission Tomography (PET) Imaging of Thrombosis

RecruitingPhase 1Healthy volunteers welcome
  • Massachusetts General Hospital, Boston
Ages 18 to 85 · All sexes · Updated Feb 27, 2026 · NCT03830320

Mind Body Intervention for Long COVID-19

Recruiting
  • Beth Israel Deaconess Medical Center, Boston
Ages 18 to 65 · All sexes · Updated Feb 18, 2026 · NCT06045338

Influenza & COVID-19 Obstetric and Perinatal Epidemiology Study in India

RecruitingObservational study
  • Boston University School of Public Health, Global Health, Boston
Ages 18 to 50 · Women · Updated Nov 28, 2025 · NCT06168019

Sauna for Long Covid

Recruiting
  • Depression Clinical and Research Program, Boston
Ages 18 to 65 · All sexes · Updated Nov 13, 2025 · NCT05931497

LIFT: Life Improvement Trial

RecruitingPhase 2
  • Brigham and Women's Hospital, Boston
Ages 18 to 70 · All sexes · Updated Oct 22, 2025 · NCT06366724

Ventilatory and Perfusion Abnormalities in Individuals With Post-Acute Sequelae of SARS-CoV-2 Infection

RecruitingObservational studyHealthy volunteers welcome
  • Tufts Medical Center, Boston
Ages 18 to 99 · All sexes · Updated Jul 20, 2025 · NCT05866952

About Post-COVID Conditions (Long COVID)

Anyone who had COVID-19 can have ongoing symptoms. Learn about post-COVID conditions (long COVID), including symptoms, diagnosis, treatments, and prevention.

More about Post-COVID Conditions (Long COVID) on MedlinePlus

Post-COVID Conditions (Long COVID) trials in other cities

Other studies in Boston

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.