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Breast Cancer clinical trials in Los Angeles, CA
73 studies for Breast Cancer are looking for participants at sites in and around Los Angeles (within about 30 miles). Open a study to see who can join and how to contact the study team.
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Study of AZD9574 as Monotherapy and in Combination With Anti-cancer Agents in Participants With Advanced Solid Malignancies
RecruitingPhase 1/2
- Research Site, Los Angeles
Phase 3 Study of RLY-2608 + Fulvestrant vs Capivasertib + Fulvestrant as Treatment for Locally Advanced or Metastatic PIK3CA-mutant HR+/HER2- Breast Cancer
RecruitingPhase 3
- Cedars-Sinai Medical Center, Los Angeles
A Study of PHST001 in Advanced Solid Tumors
RecruitingPhase 1
- USC Norris Comprehensive Cancer Center, Los Angeles
The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)
RecruitingPhase 1/2
- UCLA Jonsson Comprehensive Cancer Center, Los Angeles
- USC Norris Comprehensive Cancer Center, Los Angeles
Phase IIIb Study of Ribociclib + ET in Early Breast Cancer
RecruitingPhase 3
- Los Angeles Cancer Network Good Samaritan, Los Angeles
A Study of Patritumab Deruxtecan (HER3-DXd) in Combination With Trastuzumab Deruxtecan (T-DXd) in Participants With HR-Positive, HER2-Low or HER2-Ultralow Unresectable or Metastatic Breast Cancer
RecruitingPhase 1/2
- Cedars-Sinai Medical Center - Samuel Oschin Comprehensive Cancer Institute, Los Angeles
A Study of Alisertib in Combination With Endocrine Therapy in Patients With HR-positive, HER2-negative Recurrent or Metastatic Breast Cancer
RecruitingPhase 2
- LA Cancer Network, Los Angeles
- UCLA Department of Medicine - Hematology/Oncology, Los Angeles
Open-Label Study of BBO-10203 in Subjects With Advanced Solid Tumors
RecruitingPhase 1
- University of California Los Angeles, Los Angeles
Beamion BCGC-1: A Study to Find a Suitable Dose of Zongertinib Used Alone and in Combination With Other Treatments to Test Whether it Helps People With Different Types of HER2+ Cancer That Has Spread
RecruitingPhase 1/2
- Ellison Medical Institute, Los Angeles
- Valkyrie Clinical Trials, Los Angeles
- University of California Los Angeles, Los Angeles
A Study of NT-175 in Adult Participants With Advanced Malignancies That Are Positive for HLA-A*02:01 and the TP53 R175H Mutation
RecruitingPhase 1
- Research Site, Los Angeles
A Clinical Study of Patritumab Deruxtecan to Treat Breast Cancer (MK-1022-016)
RecruitingPhase 3
- Los Angeles Hematology Oncology Medical Group ( Site 0026), Los Angeles
A Study to Test Inavolisib Treatments in Participants With Early-Stage, PIK3CA-Mutated Breast Cancer
RecruitingPhase 2
- Los Angeles Cancer Network, Los Angeles
A Study of Tersolisib (LY4064809/STX-478) With Other Anti-Cancer Treatments in Participants With Advanced Breast Cancer With a Genetic Change (PIK3CA)
RecruitingPhase 3
- USC/Norris Comprehensive Cancer Center, Los Angeles
A Study of Imlunestrant (LY3484356) in Premenopausal Women With Estrogen Receptor-Positive (ER+) Human Epidermal Growth Factor Receptor 2 Negative (HER2-) Early Breast Cancer
RecruitingPhase 2
- USC/Norris Comprehensive Cancer Center, Los Angeles
Women Informed to Screen Depending on Measures of Risk (Wisdom Study)
RecruitingHealthy volunteers welcome
- University of California Los Angeles, Los Angeles
A Study to Evaluate the Efficacy and Safety of Inavolisib in Combination With Phesgo Versus Placebo in Combination With Phesgo in Participants With PIK3CA-Mutated HER2-Positive Locally Advanced or Metastatic Breast Cancer
RecruitingPhase 3
- Ellison Medical Institute, Los Angeles
ROSETTA Breast-01: The Effects and Safety of Pumitamig in Patients With Triple-Negative Breast Cancer
RecruitingPhase 3
- Cedar Sinai - Samuel Oschin Cancer Center, Los Angeles
A Study of Breast Cancer Risk Factors and Outcomes of People in Florida
RecruitingObservational studyHealthy volunteers welcome
- University of California, Los Angeles (Specimen Analysis only), Los Angeles
A Study of Elacestrant Versus Standard Endocrine Therapy in Women and Men With ER+,HER2-, Early Breast Cancer With High Risk of Recurrence
RecruitingPhase 3
- USC/Norris Comprehensive Cancer Center, Los Angeles
- UCLA Department of Medicine - Hematology/Oncology, Los Angeles
A Study Evaluating the Efficacy and Safety of Multiple Treatment Combinations in Patients With Metastatic or Locally Advanced Breast Cancer
RecruitingPhase 1/2
- UCLA Health 200 Medical Plaza, Los Angeles
Open Label Study to Evaluate BL-M07D1 in HER2 Expressing Malignant Solid Tumors
RecruitingPhase 1
- START - Los Angeles, Los Angeles
- Cedars Sinai, Los Angeles
A Phase 1/1b Study of IAM1363 in HER2 Cancers
RecruitingPhase 1
- USC Norris Comprehensive Cancer Center, Los Angeles
A Study to Evaluate Safety, Tolerability and Preliminary Activity of AGX101 in Participants With Advanced Solid Tumors
RecruitingPhase 1
- USC/Norris Comprehensive Cancer Center, Los Angeles
Study of Abemaciclib and Elacestrant in Participants With Brain Metastasis Due to ER+/HER-2- Breast Cancer
RecruitingPhase 1/2
- California Research Institute, Los Angeles
Study of AMXT 1501 and DFMO in Combination With Standard Therapies in Advanced Solid Tumors
RecruitingPhase 1/2
- START Los Angeles, Los Angeles
To Study the Effect of Inavolisib in Combination With Fulvestrant in Participants With Breast Cancer
RecruitingPhase 2
- Los Angeles Cancer Network, Los Angeles
A Study Evaluating the Efficacy and Safety of Inavolisib Plus CDK4/6 Inhibitor and Letrozole vs Placebo + CDK4/6i and Letrozole in Participants With Endocrine-Sensitive PIK3CA-Mutated, Hormone Receptor-Positive, HER2-Negative Advanced Breast Cancer
RecruitingPhase 3
- Ellison Medical Institute, Los Angeles
Study of the Bria-IMT Regimen and CPI vs Physicians' Choice in Advanced Metastatic Breast Cancer.
RecruitingPhase 3
- Los Angeles Cancer Network, Los Angeles
- Cedars-Sinai Cancer at Cedars-Sinai Medical Facility, Los Angeles
- Los Angeles Cancer Network_Century City, Los Angeles
- and 3 more
FT836 With or Without Chemotherapy and/or Monoclonal Antibodies, in Participants With Advanced Solid Tumors
RecruitingPhase 1
- University of Southern California, Los Angeles
Evaluating the Addition of Adjuvant Chemotherapy to Ovarian Function Suppression Plus Endocrine Therapy in Premenopausal Patients With pN0-1, ER-Positive/HER2-Negative Breast Cancer and an Oncotype Recurrence Score Less Than or Equal to 25
RecruitingPhase 3
- The Angeles Clinic and Research Institute - West Los Angeles Office, Los Angeles
- Kaiser Permanente Los Angeles Medical Center, Los Angeles
- Kaiser Permanente West Los Angeles, Los Angeles
- and 2 more
Safety, PK and Efficacy of QXL138AM in Patients With Solid Tumors and Multiple Myeloma
RecruitingPhase 1
- University of Southern California, Los Angeles
- Cedars-Sanai Medical Center - Samuel Oschin Comprehensive Cancer, Los Angeles
- Cedars-Sanai Medical Center, Los Angeles
Study of ECI830 Single Agent or in Combination in Patients With Advanced HR+/HER2- Breast Cancer and in Patients With Other Advanced Solid Tumors
RecruitingPhase 1/2
- University of California LA, Los Angeles
A Study of Mutant Selective-Inhibitor (CGT6297), in Patients With Advanced Solid Tumors
RecruitingPhase 1
- START Los Angeles, Los Angeles
A Pivotal Phase II Clinical Trial of Utidelone Injection Plus Capecitabine in HER2-negative Breast Cancer Patients With Brain Metastases
RecruitingPhase 2
- Univ. of California Los Angeles, Los Angeles
FIH Study of RGT-419B Alone and With Endocrine Therapy in HR-Positive, HER2-Negative Advanced/Metastatic Breast Cancer
RecruitingPhase 1
- University California, Los Angeles, Los Angeles
A Study of MGC026 in Participants With Advanced Solid Tumors
RecruitingPhase 1
- The Angeles Clinic and Research Institute, Los Angeles
IIT2023-09-Chung-UpfrontTAD: Upfront TAD/SNB in Patients With Breast Cancer With Nodal Metastases
RecruitingPhase 2
- Cedars-Sinai Medical Center, Samuel Oschin Comprehensive Cancer Institute, Los Angeles
A Study of Izalontamab Brengitecan Versus Chemotherapy in Participants With Previously Untreated, Locally Advanced, Recurrent Inoperable, or Metastatic Triple-negative Breast Cancer Ineligible for Anti-PD(L)1 Drugs (IZABRIGHT-Breast01)
RecruitingPhase 2/3
- USC/Norris Comprehensive Cancer Center, Los Angeles
- Valkyrie Clinical Trials, Los Angeles
Tart Cherry and Omega-3's for Aromatase Inhibitor Musculoskeletal Symptoms
RecruitingEarly phase 1
- Cedars-Sinai Medical Center, Los Angeles
E-Mindfulness Approaches for Living After Breast Cancer
RecruitingPhase 3
- Kaiser Permanente Los Angeles Medical Center, Los Angeles
- Los Angeles General Medical Center, Los Angeles
- USC / Norris Comprehensive Cancer Center, Los Angeles
- and 1 more
Rinatabart Sesutecan (Rina-S, PRO1184, GEN1184) for Advanced Solid Tumors (GCT1184-01/ PRO1184-001)
RecruitingPhase 1/2
- University of California Los Angeles Medical Center, Los Angeles
Testing the Safety and Efficacy of the Combination of Two Anti-cancer Drugs, ZEN003694 and Abemaciclib, for Adult and Pediatric Patients (12-17 Years) With Metastatic or Unresectable NUT Carcinoma, Breast Cancer and Other Solid Tumors
RecruitingPhase 1
- Keck Medicine of USC Koreatown, Los Angeles
- Los Angeles General Medical Center, Los Angeles
- USC / Norris Comprehensive Cancer Center, Los Angeles
Phase I Study of [177Lu]Lu-NNS309 in Patients With Pancreatic, Lung, Breast and Colorectal Cancers
RecruitingPhase 1
- University of California LA, Los Angeles
Study of RGT-490 in Patients With PIK3CA-Mutated Advanced Solid Tumors
RecruitingPhase 1
- START Los Angeles, Los Angeles
First-in-Human Study of Tersolisib (STX-478) as Monotherapy and in Combination With Other Antineoplastic Agents in Participants With Advanced Solid Tumors
RecruitingPhase 1/2
- Ellison Clinic at Saint John's, Los Angeles
Brain Health in Breast Cancer Survivors
RecruitingObservational studyHealthy volunteers welcome
- University of California at Los Angeles, Los Angeles
Sapanisertib and Serabelisib (PIKTOR) in Various Combinations in Patients With HR+/HER2- Advanced/Metastatic Breast Cancer
RecruitingPhase 1/2
- START Los Angeles, Los Angeles
EXoPERT EMERALD Clinical Study
RecruitingObservational studyHealthy volunteers welcome
- City of Hope Duarte Cancer Center, Los Angeles
A Long-term Treatment Extension Study of Niraparib in Participants Who Completed a Prior GlaxoSmithKline/TESARO-sponsored Niraparib Study
RecruitingPhase 2
- GSK Investigational Site, Los Angeles
Breast Cancer Screening Adherence for Women at Moderate Risk for Breast Cancer
RecruitingObservational studyHealthy volunteers welcome
- Los Angeles General Medical Center, Los Angeles
- USC / Norris Comprehensive Cancer Center, Los Angeles
Phase 3 Study of Gedatolisib as First-Line Treatment for Patients With HR-Positive, HER2-Negative Advanced Breast Cancer (VIKTORIA-2)
RecruitingPhase 3
- UCLA Hematology Oncology Santa Monica, Los Angeles
Core Biopsies for Establishing a Breast Tumor Tissue Repository
RecruitingObservational study
- USC Norris Comprehensive Cancer Center, Los Angeles
I-SPY TRIAL: Neoadjuvant and Personalized Adaptive Novel Agents to Treat Breast Cancer
RecruitingPhase 2
- University of Southern California, Los Angeles
A Study to Learn About the Study Medicine Called PF-07248144 in Combination With Fulvestrant in People With HR-positive, HER2-negative Advanced or Metastatic Breast Cancer Who Progressed After a Prior Line of Treatment.
RecruitingPhase 3
- Los Angeles Cancer Network - Good Samaritan, Los Angeles
- Los Angeles Hematology Oncology Medical Group, Los Angeles
Randomized Feasibility Trial for Mesh in Pre-Pectoral Reconstruction
Recruiting
- University of California Los Angeles, Los Angeles
Comparative Effectiveness Trial of Two Supportive Cancer Care Delivery Models for Adults With Cancer
Recruiting
- Oncology Institute for Hope and Innovation, Los Angeles
De-Escalation of Breast Radiation Trial for Hormone Sensitive, HER-2 Negative, Oncotype Recurrence Score Less Than or Equal to 18 Breast Cancer (DEBRA)
RecruitingPhase 3
- Kaiser Permanente Los Angeles Medical Center, Los Angeles
- Los Angeles General Medical Center, Los Angeles
- USC / Norris Comprehensive Cancer Center, Los Angeles
- and 1 more
Reinvigorating TNBC Response to Immunotherapy With Combination Myeloid Inhibition and Radiation
RecruitingPhase 2
- Cedars-Sinai Medical Center, Los Angeles
SDM POSSIBLE: A Breast Cancer Treatment Decision Aid for Women 70+ With Low-Risk Stage I Breast Cancers
Recruiting
- Beckman Research Institute of the City of Hope, Los Angeles
Access to Genetic Testing in Underserved Patients With Cancer
RecruitingHealthy volunteers welcome
- USC / Norris Comprehensive Cancer Center, Los Angeles
Gene Modified Immune Cells After Conditioning Regimen for the Treatment of Stage IIIC or IV Melanoma or Metastatic Solid Tumors
RecruitingPhase 1
- UCLA / Jonsson Comprehensive Cancer Center, Los Angeles
A Validation Study to Determine Concordance of Liquid Biopsy and Breast Cancer Diagnosis
RecruitingObservational study
- Keck Medicine of USC Koreatown, Los Angeles
- Los Angeles General Medical Center, Los Angeles
- USC / Norris Comprehensive Cancer Center, Los Angeles
A Study of CLSP-1025 in Adult Patients With Solid Tumors That Harbor the p53 R175H Mutation
RecruitingPhase 1
- USC - Norris Comprehensive Cancer Center, Los Angeles
Contrast Enhanced Ultrasound Medical Imaging for Identifying Breast Masses
RecruitingPhase 1
- Los Angeles County-USC Medical Center, Los Angeles
- USC / Norris Comprehensive Cancer Center, Los Angeles
Project SOAR (Speaking Our African American Realities) Awakenings for Black American Women Diagnosed With Breast Cancer
Recruiting
- UCLA, Los Angeles
A Study of MT-4561 in Patients With Various Advanced Solid Tumors
RecruitingPhase 1/2
- University of Southern California, Los Angeles
Trastuzumab Deruxtecan Alone or in Combination With Anastrozole for the Treatment of Early Stage HER2 Low, Hormone Receptor Positive Breast Cancer
RecruitingPhase 2
- UCLA / Jonsson Comprehensive Cancer Center, Los Angeles
Utilizing Advocates and Supporters to Increase Lung Cancer Screening Rates in Eligible Participants
RecruitingHealthy volunteers welcome
- UCLA / Jonsson Comprehensive Cancer Center, Los Angeles
S1501 Dual Observational and Randomized Cohort Study of Patients With Metastatic HER-2+ Breast Cancer at Risk of Cardiac Toxicity
RecruitingPhase 3
- USC / Norris Comprehensive Cancer Center, Los Angeles
A Study to Evaluate TROP2 ADC LCB84 Single Agent and in Combination With an Anti-PD-1 Ab in Advanced Solid Tumors
RecruitingPhase 1/2
- Cedars Sinai Medical Center, Los Angeles
A Phase 2 Study of PCS6422 With Capecitabine in Patients With Advanced or Metastatic Breast Cancer
RecruitingPhase 2
- Valkyrie Clinical Trials, Los Angeles
A Trial of AMXI-5001 for Treatment in Patients With Advanced Malignancies
RecruitingPhase 1/2
- University of California, Los Angles (UCLA) Department of Medicine - Hematology/Oncology, Los Angeles
Clinical Validation of the Role of microRNA Binding Site Mutations in Cancer Risk, Prevention and Treatment
RecruitingObservational studyHealthy volunteers welcome
- MiraKind, Los Angeles
About Breast Cancer
Breast cancer is a cancer that starts in the breast tissue, when cells change and grow out of control. These extra cells can form a mass called a tumor.
More about Breast Cancer on MedlinePlus
Breast Cancer trials in other cities
- New York City, NY136 studies
- Houston, TX126 studies
- Boston, MA112 studies
- Nashville, TN81 studies
- Edison, NJ68 studies
- St. Louis, MO64 studies
- Queens, NY64 studies
- Durham, NC64 studies
- Chicago, IL59 studies
- Philadelphia, PA56 studies
- Dallas, TX55 studies
- San Antonio, TX47 studies
Other studies in Los Angeles
- Non-Small Cell Lung Cancer87 studies
- Cancer (all types)74 studies
- Prostate Cancer61 studies
- Colorectal Cancer59 studies
- Metastatic Cancer57 studies
- Ovarian Cancer50 studies
- Lung Cancer45 studies
- Head and Neck Squamous Cell Carcinoma42 studies
- Pancreatic Cancer35 studies
- Endometrial Cancer34 studies
- Melanoma34 studies
- Triple-Negative Breast Cancer27 studies
From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.