Home › Cardiovascular Disease › Pennsylvania
Cardiovascular Disease clinical trials in Pennsylvania
35 studies for Cardiovascular Disease are looking for participants at sites in Pennsylvania.
Cities in Pennsylvania
ELEVATE-HFpEF Clinical Study
- Lancaster General Hospital, Lancaster
- Lankenau Institute for Medical Research, Wynnewood
Recruiting
Ages 40 and older · All sexes · Updated Oct 2, 2026 · NCT06678841A Randomized Placebo-procedure Controlled Trial of the Enhancor System (PULmonary Artery Denervation) to Evaluate Safety and Efficacy in Patients With Combined Pre- and Post-capillary Pulmonary Hypertension Associated With Left Heart Disease
- University of Pittsburgh Medical Center, Mechanicsburg
Recruiting
Ages 18 to 85 · All sexes · Updated Oct 1, 2026 · NCT07214376A Study of Clazakizumab (LY5724886) in Adults With Elevated hsCRP and at Increased Risk for Cardiovascular Event
- Suburban Research Associates, West Chester
- Cardiology Consultants of Philadelphia Yardley, Yardley
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 30, 2026 · NCT07783802EASi-PROTKT™ - A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease
- Heritage Valley Medical Group, Beaver
- Capital Area Research, LLC, Camp Hill
- Thomas Jefferson University, Philadelphia
- and 8 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 30, 2026 · NCT07064473Transition to Cardiac Rehabilitation (T2CR) to Address Barriers of Multimorbidity and Frailty
- VA Pittsburgh Healthcare System University Drive Division, Pittsburgh, PA, Pittsburgh
Recruiting
Ages 18 and older · All sexes · Updated Sep 29, 2026 · NCT06244199Inclisiran Versus Placebo for the Prevention of Major Adverse Cardiovascular and Limb Events in Patients Undergoing Percutaneous Coronary Intervention or Peripheral Endovascular Intervention
- St. Luke's University Health Network, Bethlehem
- Capital Area Research LLC, Camp Hill
- Wellspan Chambersburg Hospital, Chambersburg
- and 3 more
RecruitingPhase 4
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT06909565Treatment With Aspirin After Preeclampsia: TAP Trial
- University of Pittsburgh Magee-Womens Hospital, Pittsburgh
RecruitingPhase 4
Ages 18 to 55 · Women · Updated Sep 22, 2026 · NCT06281665A Study to See if Lepodisiran Can Reduce Plaque in Coronary Arteries of Adults With Elevated Lp(a) Who Have Had Heart Events or Are at High Risk
- Heart and Vascular Research at WellSpan Health, York
RecruitingPhase 3
Ages 45 to 80 · All sexes · Updated Sep 22, 2026 · NCT07613294Product Surveillance Registry
- Allentown
- Bethlehem
- Danville
- and 6 more
RecruitingObservational study
All ages · All sexes · Updated Sep 18, 2026 · NCT01524276Zilebesiran in Patients With Hypertension Not Adequately Controlled and With Either Established Cardiovascular Disease or High Risk for Cardiovascular Disease
- Clinical Trial Site, Camp Hill
- Clinical Trial Site, Danville
- Clinical Trial Site, Horsham
- and 4 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 18, 2026 · NCT07181109Zenith® Fenestrated+ Clinical Study
- Hospital of the University of Pennsylvania, Philadelphia
- University of Pittsburgh Medical Center, Pittsburgh
Recruiting
Ages 18 and older · All sexes · Updated Sep 17, 2026 · NCT04875429Cerebrovascular Health and Resilience in Midlife
- University of Pittsburgh, Pittsburgh
RecruitingHealthy volunteers welcome
Ages 40 to 59 · All sexes · Updated Sep 16, 2026 · NCT06029348Transcatheter Mitral Valve Replacement With the Medtronic Intrepid™ TMVR System in Patients With Severe Symptomatic Mitral Regurgitation.
- UPMC Pinnacle Harrisburg Campus, Harrisburg
- UPMC Presbyterian, Pittsburgh
- Lankenau Medical Center, Wynnewood
Recruiting
Ages 18 and older · All sexes · Updated Sep 15, 2026 · NCT03242642Investigation of the BrioVAD System for the Treatment of Left Ventricular Heart Failure
- Thomas Jefferson University Hospital, Philadelphia
Recruiting
Ages 18 to 100 · All sexes · Updated Sep 9, 2026 · NCT06310031Feasibility of The Health Integrated Nutrition and Kidney Wellness Program
- UPMC Kidney Clinic - Wexford, Pittsburgh
- UPMC Kidney Clinic - Monroeville, Pittsburgh
- UPMC Kidney Clinic - Oakland, Pittsburgh
- and 2 more
Recruiting
Ages 18 and older · All sexes · Updated Sep 9, 2026 · NCT07518719An Open Label Extension (OLE) Study (Following Completion of CTQJ230A12301) to Evaluate Long-term Safety and Tolerability of Pelacarsen (TQJ230)
- Lancaster General Health, Lancaster
- Perelman School of Medicine, Philadelphia
- Allegheny General Hospital, Pittsburgh
RecruitingPhase 3
Ages 18 to 100 · All sexes · Updated Sep 4, 2026 · NCT07517263Safety and Performance Assessment of the Sphere-9™ Catheter and Affera™ Ablation System for the Treatment of Ventricular Tachycardia (Sphere-9 VT EFS)
- Hospital of the University of Pennsylvania, Philadelphia
Recruiting
Ages 18 to 85 · All sexes · Updated Sep 3, 2026 · NCT06703489Pragmatic Evaluation of Events And Benefits of Lipid-lowering in Older Adults
- Thomas Jefferson University, Philadelphia
- University of Pittsburgh Medical Center, Pittsburgh
RecruitingPhase 4Healthy volunteers welcome
Ages 75 and older · All sexes · Updated Sep 1, 2026 · NCT04262206A Study About How Blood Cell Growth Patterns Relate to Heart Health After Treatment for Hodgkin Lymphoma
- Children's Hospital of Philadelphia, Philadelphia
- Children's Hospital of Pittsburgh of UPMC, Pittsburgh
RecruitingObservational study
Ages 7 and older · All sexes · Updated Aug 25, 2026 · NCT05705531A Phase III Study of AZD0780 on Major Adverse CV Events in Patients With a History of ASCVD Events or at High Risk for a First Event
- Research Site, Camp Hill
- Research Site, Horsham
- Research Site, Philadelphia
- and 5 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Aug 24, 2026 · NCT07000357OCEAN(a)-PreEvent - Olpasiran Trials of Cardiovascular Events And LipoproteiN(a) Reduction to Prevent First Major Cardiovascular Events
- University of Pennsylvania, Philadelphia
- Preferred Primary Care Physicians, Inc, Pittsburgh
- Pottstown Medical Specialists Inc, Pottstown
RecruitingPhase 3
Ages 50 to 105 · All sexes · Updated Aug 21, 2026 · NCT07136012Global Paradise System US Post Approval Study
- UPMC Harrisburg, Harrisburg
- Penn Medicine, Phildelphia
RecruitingObservational study
Ages 18 and older · All sexes · Updated Aug 12, 2026 · NCT06297291PROACTIVE-HF-2 Trial Heart Failure NYHA Class II and III
- Penn State Health, Hershey
- UPMC, Pittsburgh
Recruiting
Ages 18 and older · All sexes · Updated Jun 29, 2026 · NCT05934487Trial to Evaluate Safety And Effectiveness of Mechanical Circulatory Support in Patients With Advancing Heart Failure
- Abington Memorial Hospital, Abington
- Penn State Milton S. Hershey Medical Center, Hershey
- University of Pennsylvania, Philadelphia
- and 1 more
Recruiting
Ages 18 and older · All sexes · Updated Jun 10, 2026 · NCT06526195Brain Connections for Arm Movement After Stroke
- VA Pittsburgh Healthcare System University Drive Division, Pittsburgh, PA, Pittsburgh
RecruitingHealthy volunteers welcome
Ages 45 to 90 · All sexes · Updated Jun 2, 2026 · NCT04286516Cardiometabolic Effects of Pecan Snacking in Prediabetes
- The Pennsylvania State University, University Park
Recruiting
Ages 25 to 65 · All sexes · Updated May 27, 2026 · NCT07235358Deep Brain Stimulation Motor Ventral Thalamus (VOP/VIM) for Restoration of Speech and Upper-limb Function in People With Subcortical Stroke
- University of Pittsburgh, Pittsburgh
Recruiting
Ages 18 to 75 · All sexes · Updated May 8, 2026 · NCT06303869LCAT (Lecithin Cholesterol Acyl Transferase) Natural History Study
- University of Pennsylvania, Philadelphia
RecruitingObservational study
All ages · All sexes · Updated May 6, 2026 · NCT06217588Pivotal Study for the Cardiac Performance System (CPS)
- University of Pennsylvania - Penn Presbyterian Medical Center, Philadelphia
RecruitingObservational study
Ages 18 and older · All sexes · Updated Apr 24, 2026 · NCT06870591Olpasiran Trials of Cardiovascular Events and Lipoprotein(a) Reduction - Coronary Computed Tomography Angiography Trial
- Montefiore Medical Center - Bronx, Philadelphia
RecruitingPhase 3
Ages 35 to 80 · All sexes · Updated Apr 16, 2026 · NCT07293260The EMPOWER Trial - The Carillon Mitral Contour System® in Treating Heart Failure With FMR
- Penn Medicine Lancaster General Health, Lancaster
- UPMC Pinnacle Hospitals, Mechanicsburg
- University of Pennsylvania, Philadelphia
- and 2 more
Recruiting
Ages 18 and older · All sexes · Updated Apr 13, 2026 · NCT03142152The Effects of Healthy Diets With Plant Oils on Heart and Metabolic Health
- The Pennylvania State University, University Park
RecruitingHealthy volunteers welcome
Ages 25 to 60 · All sexes · Updated Feb 2, 2026 · NCT06216678Philly CEAL- DECIDE+ Adaptation
- University of Pennsylvania, Philadelphia
RecruitingHealthy volunteers welcome
Ages 35 to 75 · All sexes · Updated Oct 1, 2025 · NCT06732102MagicTouch™Sirolimus-Coated Balloon for Treatment of Coronary Artery Lesions in Small Vessels
- University of Pittsburgh Medical center (UPMC), Pittsburgh
Recruiting
Ages 18 to 80 · All sexes · Updated Sep 11, 2025 · NCT06271590PARTNER 3 Trial - Aortic Valve-in-Valve
- University of Pennsylvania Hospital, Philadelphia
- Allegheny General Hospital, Pittsburgh
- Lankenau Medical Center, Wynnewood
Recruiting
All ages · All sexes · Updated May 10, 2024 · NCT03003299From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.