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Glioblastoma clinical trials in New York City, NY

30 studies for Glioblastoma are looking for participants at sites in and around New York City (within about 30 miles). Open a study to see who can join and how to contact the study team.

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Sonocloud-9 in Association With Carboplatin Versus Standard-of-Care Chemotherapies (CCNU or TMZ) in Recurrent GBM

RecruitingPhase 3
  • Weill Cornell Medicine, New York
  • NewYork-Presbyterian / Columbia University Irving Medical Center, New York
  • Lennox Hill Hospital, New York
Ages 18 and older · All sexes · Updated Oct 5, 2026 · NCT05902169

Ruxolitinib With Radiation and Temozolomide Compared to Radiation and Temozolomide for Newly Diagnosed Glioblastoma

RecruitingPhase 2
  • New York University Langone's Perlmutter Cancer Institute, New York
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT06991101

Testing the Addition of an Anti-cancer Drug, Selinexor, to the Usual Chemotherapy Treatment (Temozolomide) for Brain Tumors That Have Returned After Previous Treatment

RecruitingPhase 1/2
  • Laura and Isaac Perlmutter Cancer Center at NYU Langone, New York
  • NYP/Columbia University Medical Center/Herbert Irving Comprehensive Cancer Center, New York
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT05432804

A Trial to Evaluate Multiple Regimens in Newly Diagnosed and Recurrent Glioblastoma

RecruitingPhase 2/3
  • Icahn School of Medicine at Mount Sinai, New York
  • Columbia University Medical Center, New York
  • Memorial Sloan Kettering Cancer Center*, New York
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT03970447

Study of Silevertinib With Temozolomide for the Treatment of Newly Diagnosed GBM With Unmethylated MGMT and EGFRvIII

RecruitingPhase 2
  • Columbia University Irving Medical Center, New York
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07326566

A Feasibility Study to Evaluate the Safety of the TheraSphere Glioblastoma (GBM) Device in Patients With Recurrent GBM

RecruitingPhase 1
  • Lenox Hill Hospital, New York
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT05303467

A Study of Debio 0123 in Combination With Temozolomide in Adult Participants With Recurrent or Progressive Glioblastoma and of Debio 0123 in Combination With Temozolomide and Radiotherapy in Adult Participants With Newly Diagnosed Glioblastoma

RecruitingPhase 1/2
  • New York University Langone Medical Center, New York
  • David H. Koch Center for Cancer Care at Memorial Sloan Kettering Cancer Center, New York
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT05765812

Temporally-Modulated Pulsed Radiation Therapy Versus Standard Radiation Therapy for the Treatment of Newly Diagnosed, IDH Wildtype, MGMT-Unmethylated Glioblastoma

RecruitingPhase 3
  • NYP/Columbia University Medical Center/Herbert Irving Comprehensive Cancer Center, New York
Ages 18 and older · All sexes · Updated Sep 10, 2026 · NCT07452458

A Study of PRMT5 Inhibitor BAY 3713372 in Participants With MTAP-deleted Solid Tumors

RecruitingPhase 1/2
  • Icahn School of Medicine at Mount Sinai - Oncology, New York
  • Memorial Sloan Kettering Cancer Center New York - Main Campus, New York
Ages 18 and older · All sexes · Updated Sep 10, 2026 · NCT06914128

Study of ABBV-637 or ABBV-155 With ERAS-801 for People With Glioblastoma

RecruitingPhase 1
  • Memorial Sloan Kettering Cancer Center (All Protocol Activities), New York
Ages 18 and older · All sexes · Updated Sep 9, 2026 · NCT06934889

Testing the Addition of an Anti-Cancer Drug, Triapine, to the Usual Radiation Therapy for Recurrent Glioblastoma or Astrocytoma

RecruitingPhase 1
  • Laura and Isaac Perlmutter Cancer Center at NYU Langone, New York
  • NYP/Columbia University Medical Center/Herbert Irving Comprehensive Cancer Center, New York
Ages 18 and older · All sexes · Updated Sep 2, 2026 · NCT06860594

SIGMA (Safusidenib in IDH1 Mutant Glioma Maintenance)

RecruitingPhase 3
  • NYU Langone Health, New York
  • Icahn School of Medicine at Mount Sinai, New York
  • Columbia University Medical Center, New York
  • and 1 more
Ages 18 and older · All sexes · Updated Aug 28, 2026 · NCT05303519

INdividualized Screening Trial of Innovative Glioblastoma Therapy (INSIGhT)

RecruitingPhase 2
  • Memorial Sloan Kettering Cancer Center, New York
Ages 18 and older · All sexes · Updated Aug 19, 2026 · NCT02977780

A Phase 1 Safety and Dose Finding Study of GLIX1 in Adults With Recurrent or Progressive High-grade Glioma

RecruitingPhase 1
  • NYU Langone Health, New York
Ages 18 and older · All sexes · Updated Jul 30, 2026 · NCT07464925

Alpha Radiation Emitters Device (DaRT) for the Treatment of Recurrent Glioblastoma

Recruiting
  • NYU Langone Health, New York
Ages 18 to 85 · All sexes · Updated Jul 21, 2026 · NCT06910306

Adjuvant Temozolomide ± 5-Aminolevulinic Acid + Low Intensity Diffuse Ultrasound Sonodynamic Therapy System for Newly Diagnosed Glioblastoma

RecruitingPhase 2
  • New York Langone, New York
  • Columbia University, New York
  • Memorial Sloan Kettering Cancer Center, New York
Ages 18 to 80 · All sexes · Updated Jul 17, 2026 · NCT07225621

DOC1021 Dendritic Cell Immunotherapy for Treatment of Newly Diagnosed Adult Glioblastoma (GBM)

RecruitingPhase 2
  • Lenox Hill Hospital, New York
Ages 18 and older · All sexes · Updated Jul 1, 2026 · NCT06805305

A Study of 177Lu-PSMA-617 in People With Gliomas

RecruitingPhase 1
  • Memorial Sloan Kettering Cancer Center (All Protocol Activities), New York
Ages 18 and older · All sexes · Updated Jun 4, 2026 · NCT07223034

Super-selective Intra-arterial Repeated Infusion of Cetuximab for the Treatment of Newly Diagnosed Glioblastoma

RecruitingPhase 1/2
  • Lenox Hill Brain Tumor Center, New York
Ages 18 and older · All sexes · Updated Jun 1, 2026 · NCT02861898

Repeated Superselective Intraarterial Cerebral Infusion (SIACI) of Bevacizumab With Temozolomide and Radiation Compared to Temozolomide and Radiation Alone in Newly Diagnosed GBM

RecruitingPhase 3
  • Lenox Hill Brain Tumor Center, New York
Ages 18 and older · All sexes · Updated Jun 1, 2026 · NCT05271240

Repeated Super-selective Intraarterial Cerebral Infusion of Bevacizumab (Avastin) for Treatment of Relapsed GBM and AA

RecruitingPhase 1/2
  • Lenox Hill Brain Tumor Center, New York
Ages 18 and older · All sexes · Updated Jun 1, 2026 · NCT01269853

Surgical Tissue Flap to Bypass the Blood Brain Barrier in Glioblastoma

Recruiting
  • Lenox Hill Brain Tumor Center, New York
Ages 18 and older · All sexes · Updated Jun 1, 2026 · NCT05954858

Omental Tissue Autograft in Human Recurrent Glioblastoma Multiforme (rGBM)

Recruiting
  • Lenox Hill Brain Tumor Center, New York
Ages 18 and older · All sexes · Updated Jun 1, 2026 · NCT05979064

Oral Capecitabine and Temozolomide (CAPTEM) for Newly Diagnosed GBM

RecruitingPhase 1/2
  • Lenox Hill Brain Tumor Center, New York
Ages 18 to 74 · All sexes · Updated Jun 1, 2026 · NCT03213002

Safety and Tolerability of TNG456 Alone and in Combination With Abemaciclib in Patients With Solid Tumors With MTAP Loss

RecruitingPhase 1/2
  • NYU Langone Health, New York
  • Memorial Sloan Kettering Cancer Center, New York
Ages 18 and older · All sexes · Updated Apr 13, 2026 · NCT06810544

Super Selective Intra-arterial Repeated Infusion of Cetuximab (Erbitux) With Reirradiation for Treatment of Relapsed/Refractory GBM, AA, and AOA

RecruitingPhase 2
  • Lenox Hill Brain Tumor Center, New York
Ages 18 and older · All sexes · Updated Apr 13, 2026 · NCT02800486

Trastuzumab Deruxtecan (T-DXd) for People With Brain Cancer

RecruitingPhase 2
  • Memorial Sloan Kettering Cancer Center (All Protocol Activities), New York
Ages 18 and older · All sexes · Updated Feb 23, 2026 · NCT06058988

SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

RecruitingObservational study
  • Massive Bio SYNERGY-AI site, New York
All ages · All sexes · Updated Oct 28, 2025 · NCT03452774

Evaluation of Eflornithine Plus Temozolomide in Patients With Newly Diagnosed Glioblastoma or Astrocytoma

RecruitingPhase 1
  • Columbia University Medical Center - Herbert Irving Pavilion, New York
Ages 18 and older · All sexes · Updated Jun 25, 2025 · NCT05879367

Glioblastoma trials in other cities

Other studies in New York City

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.