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Glioblastoma clinical trials in Houston, TX

25 studies for Glioblastoma are looking for participants at sites in and around Houston (within about 30 miles). Open a study to see who can join and how to contact the study team.

GPC-3 CAR T CELLS FOR Recurrent GPC-3 Positive Glioblastoma

RecruitingPhase 1
  • Baylor St. Luke's Medical Center, Houston
Ages 21 to 70 · All sexes · Updated Sep 30, 2026 · NCT06815432

A Feasibility Study to Evaluate the Safety of the TheraSphere Glioblastoma (GBM) Device in Patients With Recurrent GBM

RecruitingPhase 1
  • MD Anderson Cancer Center, Houston
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT05303467

A Study of Repotrectinib in Pediatric and Young Adult Subjects Harboring ALK, ROS1, OR NTRK1-3 Alterations

RecruitingPhase 1/2
  • Baylor College of Medicine, Houston
Up to age 25 · All sexes · Updated Sep 25, 2026 · NCT04094610

MSC-DNX-2401 in Treating Patients With Recurrent High-Grade Glioma

RecruitingPhase 1
  • M D Anderson Cancer Center, Houston
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT03896568

Anti-GD2 ADC M3554 in Advanced Solid Tumors

RecruitingPhase 1
  • The University of Texas MD Anderson Cancer Center, Houston
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT06641908

Targeted Pediatric High-Grade Glioma Therapy

RecruitingObservational study
  • Texas Children's Hospital, Houston
12 Months – 39 Years · All sexes · Updated Sep 8, 2026 · NCT05839379

HSV G207 in Children With Recurrent or Refractory Cerebellar Brain Tumors

RecruitingPhase 1
  • MD Anderson Cancer Center, Houston
36 Months – 22 Years · All sexes · Updated Sep 4, 2026 · NCT03911388

Study of Olutasidenib and Temozolomide in HGG

RecruitingPhase 2
  • Texas Children's Hospital, Houston
Ages 12 to 39 · All sexes · Updated Sep 1, 2026 · NCT06161974

SIGMA (Safusidenib in IDH1 Mutant Glioma Maintenance)

RecruitingPhase 3
  • MD Anderson Cancer Center, Houston
Ages 18 and older · All sexes · Updated Aug 28, 2026 · NCT05303519

Study of 203Pb-RMX-VH-PIB Dosimetry and Biodistribution in Patients With Glioblastoma Multiform (GBM) and Pancreatic Ductal Adenocarcinoma (PDAC)

RecruitingPhase 1
  • Excel Diagnostics & Nuclear Oncology Center, Houston
Ages 18 and older · All sexes · Updated Aug 7, 2026 · NCT07733674

A Trial to Evaluate Multiple Regimens in Newly Diagnosed and Recurrent Glioblastoma

RecruitingPhase 2/3
  • University of Texas - MD Anderson Cancer Center, Houston
Ages 18 and older · All sexes · Updated Jul 30, 2026 · NCT03970447

A Phase I/II Study of IVONESCIMAB in Recurrent Glioblastoma

RecruitingPhase 1/2
  • The University of Texas M. D. Anderson Cancer Center, Houston
  • The University of Texas MD Anderson Cancer Center, Houston
Ages 18 and older · All sexes · Updated Jul 21, 2026 · NCT06672575

Customized Neuro-Imaging Referenced Symptom Video for the Reduction of Patient and Caregiver Anxiety Around Radiation Treatment for Brain Tumors

RecruitingHealthy volunteers welcome
  • M D Anderson Cancer Center, Houston
Ages 18 and older · All sexes · Updated Jul 20, 2026 · NCT04479696

Chemotherapy and Radiation Therapy for the Treatment of IDH Wildtype Gliomas or Non-histological (Molecular) Glioblastomas

RecruitingPhase 2
  • M D Anderson Cancer Center, Houston
Ages 18 and older · All sexes · Updated Jul 16, 2026 · NCT04623931

DOC1021 Dendritic Cell Immunotherapy for Treatment of Newly Diagnosed Adult Glioblastoma (GBM)

RecruitingPhase 2
  • UTHealth Houston, Houston
  • Baylor College of Medicine, Houston
Ages 18 and older · All sexes · Updated Jul 1, 2026 · NCT06805305

Lorlatinib for Newly-Diagnosed High-Grade Glioma With ROS or ALK Fusion

RecruitingEarly phase 1Healthy volunteers welcome
  • Texas Children's Hospital, Houston
Ages 1 to 21 · All sexes · Updated Jun 29, 2026 · NCT06333899

Study of Ribociclib and Everolimus in HGG and DIPG or Ribociclib and Temozolomide in DHG, H3G34-mutant

RecruitingPhase 2
  • Texas Children's Hospital, Houston
12 Months – 39 Years · All sexes · Updated May 29, 2026 · NCT05843253

Safety and Tolerability of TNG456 Alone and in Combination With Abemaciclib in Patients With Solid Tumors With MTAP Loss

RecruitingPhase 1/2
  • MD Anderson Cancer Center, Houston
Ages 18 and older · All sexes · Updated Apr 13, 2026 · NCT06810544

HSV-tk and XRT and Chemotherapy for Newly Diagnosed GBM

RecruitingPhase 1/2
  • Houston Methodist Neurological Institute, Houston
Ages 18 and older · All sexes · Updated Mar 30, 2026 · NCT03603405

HSV-tk + Valacyclovir + SBRT + Chemotherapy for Recurrent GBM

RecruitingPhase 1/2
  • Houston Methodist Neurological Institute, Houston
Ages 18 and older · All sexes · Updated Mar 30, 2026 · NCT03596086

SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

RecruitingObservational study
  • Massive Bio SYNERGY-AI site, Houston
All ages · All sexes · Updated Oct 28, 2025 · NCT03452774

A Study to Evaluate TROP2 ADC LCB84 Single Agent and in Combination With an Anti-PD-1 Ab in Advanced Solid Tumors

RecruitingPhase 1/2
  • MD Anderson Cancer Center, Houston
Ages 18 and older · All sexes · Updated Sep 24, 2025 · NCT05941507

Evaluation of Eflornithine Plus Temozolomide in Patients With Newly Diagnosed Glioblastoma or Astrocytoma

RecruitingPhase 1
  • UT MD Anderson Cancer Center, Houston
Ages 18 and older · All sexes · Updated Jun 25, 2025 · NCT05879367

Glioblastoma trials in other cities

Other studies in Houston

From ClinicalTrials.gov, data retrieved Oct 1, 2026. Each study sets its own eligibility; the study team decides who can join.