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Multiple Myeloma clinical trials in New York City, NY

60 studies for Multiple Myeloma are looking for participants at sites in and around New York City (within about 30 miles). Open a study to see who can join and how to contact the study team.

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Study of IgPro20 to Prevent Infection in People With Multiple Myeloma and Hypogammaglobulinemia

RecruitingPhase 2
  • Mount Sinai Hospital, New York
  • Memorial Sloan Kettering Cancer Center (All Protocol Activities), New York
Ages 18 and older · All sexes · Updated Oct 5, 2026 · NCT06976476

A Study of a Plant-Based Diet and Dietary Supplements in People With Smoldering Multiple Myeloma (SMM) or Monoclonal Gammopathy of Undetermined Significance (MGUS)

Recruiting
  • Memorial Sloan Kettering Cancer Center (All Protocol Activities), New York
Ages 18 and older · All sexes · Updated Oct 5, 2026 · NCT06055894

Limited-duration Teclistamab

RecruitingPhase 2
  • Columbia University, New York
Ages 18 and older · All sexes · Updated Oct 5, 2026 · NCT05932680

A Study of Melphalan With or Without Siltuximab in People With Multiple Myeloma Having an Autologous Stem Cell Transplant

RecruitingPhase 2
  • Memorial Sloan Kettering Cancer Center (All protocol activities), New York
Ages 60 and older · All sexes · Updated Oct 1, 2026 · NCT06679829

A Study Comparing AZD0120, a Dual-targeted CAR-T Against B-cell Maturation Antigen (BCMA) and CD19, Versus Standard Regimens in Participants With Relapsed Refractory Multiple Myeloma (DURGA-4)

RecruitingPhase 3
  • Research Site, New York
  • Research Site, New York
Ages 18 and older · All sexes · Updated Sep 29, 2026 · NCT07391657

A Study of JNJ-79635322 in Participants With Relapsed or Refractory Multiple Myeloma or Previously Treated Amyloid Light-chain (AL) Amyloidosis

RecruitingPhase 1
  • Icahn School of Medicine at Mt. Sinai, New York
  • Memorial Sloan Kettering Cancer Center, New York
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT05652335

A Phase 1b/2 Study of Sonrotoclax (BGB-11417) as Monotherapy and in Various Combinations With Dexamethasone Plus Carfilzomib, Dexamethasone Plus Daratumumab, and Dexamethasone Plus Pomalidomide in Multiple Myeloma

RecruitingPhase 1/2
  • Memorial Sloan Kettering Cancer Center Mskcc, New York
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT04973605

A Long-term Study for Participants Previously Treated With Ciltacabtagene Autoleucel

RecruitingPhase 4
  • Mount Sinai Medical Center, New York
  • Memorial Sloan Kettering Cancer Center, New York
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT05201781

A Study Comparing JNJ-79635322 and an Anti-B-cell Maturation Antigen (BCMA)xCD3 Bispecific Antibody in Participants With Relapsed or Refractory Multiple Myeloma

RecruitingPhase 3
  • Mount Sinai Chelsea, New York
  • Laura and Isaac Perlmutter Cancer Center NYU ACC, New York
  • Icahn School of Medicine at Mount Sinai, New York
  • and 1 more
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT07258511

A Study Comparing JNJ-79635322 and Teclistamab in Participants With Relapsed or Refractory Multiple Myeloma

RecruitingPhase 3
  • NYU Langone Health Manhattan, New York
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT07518186

A Study to Compare Linvoseltamab and Daratumumab Treatment in High-Risk Smoldering Multiple Myeloma (HR-SMM)

RecruitingPhase 3
  • Memorial Sloan Kettering Cancer Center, New York
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT07393282

A Study to Evaluate Preventive Treatments for GPRC5D-related Oral Events

RecruitingPhase 2
  • Icahn School of Medicine at Mt. Sinai, New York
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06500884

A Study to Learn About the Effects of the Combination of Elranatamab, Daratumumab and Lenalidomide Compared With Daratumumab, Bortezomib, Lenalidomide, and Dexamethasone in Patients With Newly Diagnosed Multiple Myeloma Who Are Not Candidates for Transplant

RecruitingPhase 3
  • Memorial Sloan Kettering Cancer Center - David H. Koch Center for Cancer Care (74th Street)., New York
  • Memorial Sloan Kettering Cancer Center-Main Campus, New York
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT05623020

A Study of IBI3003 in Subjects With Relapsed or Refractory Multiple Myeloma

RecruitingPhase 1/2
  • Memorial Sloan Kettering, New York
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT07336472

A Study of Talquetamab in Participants With Relapsed or Refractory Multiple Myeloma

RecruitingPhase 2
  • Mount Sinai Medical Center, New York
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT04634552

A Study of Teclistamab in Combination With Daratumumab and Lenalidomide (Tec-DR) and Talquetamab in Combination With Daratumumab and Lenalidomide (Tal-DR) in Participants With Newly Diagnosed Multiple Myeloma

RecruitingPhase 3
  • Perlmutter Cancer Center at NYU Langone Health, New York
  • Memorial Sloan Kettering Cancer Center, New York
  • Weill Cornell Medical College, New York
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT05552222

A Study of mRNA-2808 in Participants With Relapsed or Refractory Multiple Myeloma

RecruitingPhase 1/2
  • Tisch Cancer Institute at Mount Sinai, New York
  • Memorial Sloan-Kettering Cancer Center, New York
Ages 18 and older · All sexes · Updated Sep 23, 2026 · NCT07116616

TAPUR: Testing the Use of Food and Drug Administration (FDA) Approved Drugs That Target a Specific Abnormality in a Tumor Gene in People With Advanced Stage Cancer

RecruitingPhase 2
  • Manhattan Eye, Ear, and Throat Hospital, New York
  • Staten Island University Hospital, New York
Ages 12 and older · All sexes · Updated Sep 22, 2026 · NCT02693535

A Study to Assess A Change in Disease Activity and Adverse Events of Intravenous Etentamig and Daratumumab (Etentamig+D) Compared to Daratumumab, Lenalidomide, and Dexamethasone (DRd) in Adult Participants With Newly Diagnosed Multiple Myeloma Not Eligible for Transplant

RecruitingPhase 2/3
  • Icahn School of Medicine at Mount Sinai /ID# 277844, New York
  • Memorial Sloan Kettering Cancer Center - New York - York Avenue /ID# 277946, New York
  • Weill Cornell Medicine Myeloma Center /ID# 278216, New York
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07095452

Study to Assess Safety of HDP-101 in Patients With Relapsed Refractory Multiple Myeloma

RecruitingPhase 1/2
  • Mount Sinai, The Tisch Cancer Instutute, New York
Ages 18 and older · All sexes · Updated Sep 17, 2026 · NCT04879043

Study of Arlocabtagene Autoleucel (BMS-986393) a GPRC5D-directed CAR T Cell Therapy in Adult Participants With Relapsed or Refractory Multiple Myeloma

RecruitingPhase 2
  • Icahn School of Medicine at Mount Sinai, New York
  • Memorial Sloan Kettering Cancer Center, New York
Ages 18 and older · All sexes · Updated Sep 14, 2026 · NCT06297226

Subcutaneous Talquetamab in Elderly Patients With Multiple Myeloma in Early Relapse

RecruitingPhase 2
  • Icahn School of Medicine at Mount Sinai, New York
Ages 70 and older · All sexes · Updated Sep 14, 2026 · NCT06827860

A Study to Assess Adverse Events and Change in Disease Activity of Oral Surzetoclax Alone or in Combination With Subcutaneous and/or Oral Antimyeloma Agents in Adult Participants With Multiple Myeloma (MM)

RecruitingPhase 1/2
  • Memorial Sloan Kettering Cancer Center - New York - York Avenue /ID# 271214, New York
Ages 18 and older · All sexes · Updated Sep 14, 2026 · NCT06953960

Study of SIM0500 Alone in Participants With Relapsed or Refractory Multiple Myeloma

RecruitingPhase 1
  • Laura & Isaac Perlmutter Cancer Center at NYU Langone Health, New York
  • Icahn School of Medicine at Mount Sinai,The Tisch Cancer Institute, New York
Ages 18 and older · All sexes · Updated Aug 28, 2026 · NCT06375044

A Study to Learn About the Study Medicine Elranatamab Alone and With Daratumumab in People With Multiple Myeloma Who Have Received Other Treatments

RecruitingPhase 3
  • Memorial Sloan Kettering Cancer Center - David H. Koch Center for Cancer Care (74th Street)., New York
  • Memorial Sloan Kettering Cancer Center - Main Campus, New York
Ages 18 and older · All sexes · Updated Aug 24, 2026 · NCT05020236

AZD0305 as Monotherapy or in Combination With Anticancer Agents in Participants With Multiple Myeloma

RecruitingPhase 1/2
  • Research Site, New York
Ages 18 and older · All sexes · Updated Aug 19, 2026 · NCT06106945

A Study of an MMSET Inhibitor in Patients With Relapsed and Refractory Multiple Myeloma

RecruitingPhase 1
  • Memorial Sloan-Kettering Cancer Center, New York
Ages 18 and older · All sexes · Updated Aug 18, 2026 · NCT05651932

A Study of Teclistamab and Mezigdomide in People With Multiple Myeloma

RecruitingPhase 1
  • Memorial Sloan Kettering Cancer Center (All Protocol Activities), New York
Ages 18 and older · All sexes · Updated Aug 17, 2026 · NCT07105059

AZD0120 in Relapsed/Refractory Multiple Myeloma (DURGA-1)

RecruitingPhase 1/2
  • Research Site, New York
Ages 18 and older · All sexes · Updated Aug 17, 2026 · NCT05850234

Study of AZD0120 in Newly Diagnosed Multiple Myeloma Ineligible for ASCT

RecruitingPhase 3
  • Research Site, New York
  • Research Site, New York
  • Research Site, New York
Ages 18 and older · All sexes · Updated Aug 14, 2026 · NCT07764978

A Study to Learn About the Effects of Cemsidomide in Combination With Elranatamab in Relapsed/Refractory Multiple Myeloma Subjects

RecruitingPhase 1
  • Memorial Sloan Kettering Cancer Center, New York
Ages 18 and older · All sexes · Updated Aug 12, 2026 · NCT07280013

Delayed Toxicities Post-CAR-T

RecruitingObservational study
  • Mount Sinai, New York
  • Memorial Sloan Kettering Cancer Center, New York
Ages 18 and older · All sexes · Updated Aug 10, 2026 · NCT07665307

A Study of Voice as a Way to Monitor for Side Effects in People Receiving CAR T-Cell Therapy

RecruitingObservational study
  • Weill Cornell Medical Center (Data Analysis Only), New York
  • Memorial Sloan Kettering Cancer Center (All Protocol Activites), New York
Ages 18 and older · All sexes · Updated Aug 6, 2026 · NCT07249528

A Study to Evaluate the Efficacy of Cemsidomide + Dexamethasone in Participants With Relapsed/Refractory Multiple Myeloma

RecruitingPhase 2
  • The Tisch Cancer Institute/Mount Sinai, New York
  • Memorial Sloan Kettering Cancer Center, New York
Ages 18 and older · All sexes · Updated Aug 6, 2026 · NCT07284758

A Study of Dara-RVd and Teclistamab-RVd in People With Multiple Myeloma

RecruitingPhase 1/2
  • Memorial Sloan Kettering Cancer Center (All Protocol Activities), New York
Ages 18 and older · All sexes · Updated Jul 28, 2026 · NCT07099391

A Study to Assess Change in Disease Activity and Adverse Events (AE)s in Adult Participants With Multiple Myeloma Receiving T Cell Engaging Bi/Tri-specific Antibodies Intravenously (IV)/Subcutaneously (SC) Alone or in Combinations

RecruitingPhase 1/2
  • Mount Sinai - The Tisch Cancer Institute /ID# 272470, New York
  • Weill Cornell Medical College /ID# 272517, New York
Ages 18 and older · All sexes · Updated Jul 21, 2026 · NCT06892522

A Study to Evaluate the Safety, Effectiveness and Tolerable Dose of Arlocabtagene Autoleucel (BMS-986393) in Novel Combinations in Participants With Relapsed and/or Refractory Multiple Myeloma

RecruitingPhase 1
  • Laura and Isaac Perlmutter Cancer Center, New York
  • Memorial Sloan Kettering Cancer Center, New York
Ages 18 and older · All sexes · Updated Jul 16, 2026 · NCT06121843

A Study to Assess Adverse Events of Intravenously (IV) Infused Etentamig (ABBV-383) in Adult Participants With Relapsed or Refractory Multiple Myeloma

RecruitingPhase 1
  • Mt Sinai /ID# 251166, New York
  • Memorial Sloan Kettering Cancer Center-Koch Center /ID# 251167, New York
Ages 18 and older · All sexes · Updated Jul 13, 2026 · NCT05650632

A Study to Examine the Effects of Novel Therapy Linvoseltamab in Combination With Other Cancer Treatments for Adult Participants With Multiple Myeloma That is Resistant to Current Standard of Care Treatments

RecruitingPhase 1
  • Weill Cornell Medicine/New York Presbyterian Hospital, New York
  • New York Presbyterian Hospital Columbia University Medical Center, New York
Ages 18 and older · All sexes · Updated Jul 8, 2026 · NCT05137054

A Study of CyBorD (Cyclophosphamide, Bortezomib, Dexamethasone) Plus Daratumumab in People With Monoclonal Gammopathy of Renal Significance (MGRS)

RecruitingPhase 2
  • Weill Cornell Medical Center (Data Collection Only), New York
  • Memorial Sloan Kettering Cancer Center (All Protocol Activities), New York
Ages 18 and older · All sexes · Updated Jul 6, 2026 · NCT06083922

A Study of Elranatamab and Cyclophosphamide in People With Multiple Myeloma

RecruitingPhase 2
  • Memorial Sloan Kettering Cancer Center (All Protocol Activities), New York
Ages 18 and older · All sexes · Updated Jun 16, 2026 · NCT07454382

The Ambient Light Multiple Myeloma Study

Recruiting
  • Icahn Schoool of Medicine at Mount Sinai, New York
  • Memorial Sloan Kettering Cancer Center, New York
Ages 21 and older · All sexes · Updated Jun 12, 2026 · NCT05737732

Comparing Combinations of Drugs to Treat Newly Diagnosed Multiple Myeloma (NDMM) When a Stem Cell Transplant is Not a Medically Suitable Treatment

RecruitingPhase 3
  • NYP/Columbia University Medical Center/Herbert Irving Comprehensive Cancer Center, New York
All ages · All sexes · Updated Jun 10, 2026 · NCT05561387

Low-Dose Radiotherapy in Treating Painful Bone Metastases in Patients With Multiple Myeloma

Recruiting
  • Icahn School of Medicine at Mount Sinai, New York
Ages 18 and older · All sexes · Updated Jun 5, 2026 · NCT03858205

A Window of Opportunity Trial to Learn if Linvoseltamab is Safe and Well Tolerated, and How Well it Works in Adult Participants With Recently Diagnosed Multiple Myeloma Who Have Not Already Received Treatment

RecruitingPhase 1/2
  • Perlmutter Cancer Center, New York
  • Columbia University _ New York Presbyterian, New York
Ages 18 and older · All sexes · Updated May 13, 2026 · NCT05828511

Study of Intravenously (IV) Infused Etentamig in Combination With an Oral Cereblon E3 Ligase Modulatory Drug (CELMoD) Agent Assessing Adverse Events and Change in Disease Activity in Adult Participants With Relapsed or Refractory Multiple Myeloma

RecruitingPhase 1
  • Memorial Sloan Kettering Cancer Center - New York - York Avenue /ID# 270282, New York
Ages 18 and older · All sexes · Updated May 12, 2026 · NCT06896916

A Dietary Study for People With Multiple Myeloma

Recruiting
  • Memorial Sloan Kettering Cancer Center (All Protocol Activities), New York
Ages 18 and older · All sexes · Updated May 5, 2026 · NCT07226609

Phase 1/2 Study of Linvoseltamab in Adult Patients With Relapsed or Refractory Multiple Myeloma

RecruitingPhase 1/2
  • Icahn School of Medicine at Mount Sinai, New York
Ages 18 and older · All sexes · Updated Apr 20, 2026 · NCT03761108

Study of CAR-T Therapy in Older Patients

RecruitingObservational study
  • Memorial Sloan Kettering Cancer Center, New York
Ages 60 and older · All sexes · Updated Apr 7, 2026 · NCT04300998

A Study to Assess BMS-986453 in Participants With Relapsed and/or Refractory Multiple Myeloma

RecruitingPhase 1
  • Icahn School of Medicine at Mount Sinai, New York
  • Memorial Sloan Kettering Cancer Center, New York
Ages 18 and older · All sexes · Updated Mar 18, 2026 · NCT06153251

A Study of Talquetamab for People With Multiple Myeloma Who Have Received BCMA CAR T-Cell Therapy

RecruitingPhase 2
  • Memorial Sloan Kettering Cancer Center, New York
Ages 18 and older · All sexes · Updated Mar 4, 2026 · NCT06066346

In-Human CXCR4 Imaging of Hematologic and Solid Tumors Using [68Ga]-Pentixafor-PET

RecruitingEarly phase 1
  • Memorial Sloan Kettering Cancer Center, New York
Ages 18 and older · All sexes · Updated Feb 5, 2026 · NCT05093335

Ascertainment of Families for Genetic Studies of Familial Lymphoproliferative Disorders

RecruitingObservational studyHealthy volunteers welcome
  • Memorial Sloan Kettering Cancer Center, New York
All ages · All sexes · Updated Jan 23, 2026 · NCT00582621

CRISPR-Edited Allogeneic Anti-BCMA CAR-T Cell Therapy in Patients With Relapsed/Refractory Multiple Myeloma

RecruitingPhase 1
  • Icahn School of Medicine at Mount Sinai, New York
  • Memorial Sloan Kettering Cancer Center, New York
Ages 18 and older · All sexes · Updated Sep 25, 2025 · NCT05722418

A Study to Evaluate Safety, Drug Levels and Effectiveness of CC-92480 (BMS-986348) in Combination With Other Treatments in Participants With Relapsed or Refractory Multiple Myeloma

RecruitingPhase 1/2
  • Memorial Sloan Kettering Cancer Center, New York
Ages 18 and older · All sexes · Updated Sep 5, 2025 · NCT05372354

About Multiple Myeloma

Multiple myeloma is a cancer that begins in plasma cells, a type of white blood cell. Discover symptoms, diagnostic tests, and treatments for myeloma.

More about Multiple Myeloma on MedlinePlus

Multiple Myeloma trials in other cities

Other studies in New York City

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.