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Healthy volunteer studies in Oklahoma City, OK

36 studies at sites in and around Oklahoma City accept healthy volunteers — people without the condition being studied. Many studies pay participants for their time and travel; the amount is set by each study, so ask the study team.

Trial of Varenicline With Nicotine Lozenges and a Smartphone Medication Adherence Intervention for Smoking Cessation

RecruitingPhase 2Healthy volunteers welcomeMentions payment for participants
  • TSET Health Promotion Research Center, Oklahoma City
Ages 18 and older · All sexes · Updated Aug 19, 2026 · NCT07099638

Studying the PAGODA Algorithm for Chemotherapy Dose Changes to Prevent Unplanned Treatment Delays

RecruitingHealthy volunteers welcome
  • Mercy Hospital Oklahoma City, Oklahoma City
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT07283939

Surgical Thromboprophylaxis Practices in Oncology Patients Within the NCORP Network, STOP-VTE Study

RecruitingObservational studyHealthy volunteers welcome
  • Mercy Hospital Oklahoma City, Oklahoma City
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT07215624

Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection

RecruitingObservational studyHealthy volunteers welcome
  • Mercy Hospital Oklahoma City, Oklahoma City
Ages 40 to 75 · All sexes · Updated Oct 2, 2026 · NCT05334069

Testing an Enhanced Digital Delivery Model for Inherited Cancer Genetic Testing in Young Adults With Cancer

RecruitingHealthy volunteers welcome
  • Mercy Hospital Oklahoma City, Oklahoma City
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT07091617

Family Communications After Genetic Testing

RecruitingHealthy volunteers welcome
  • Mercy Hospital Oklahoma City, Oklahoma City
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT07143487

Observational Study of Decentralized Urine Optical Interaction Patterns Associated With Environmental Microplastic and Nanoplastic Exposure

RecruitingObservational studyHealthy volunteers welcome
  • Decentralized / At-Home Participation (U.S.), Oklahoma City
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT07775495

A Randomized Comparison of Stage-Based Care Versus Risk Factor-Based Care for Prevention of Cardiovascular Events

RecruitingHealthy volunteers welcome
  • Hightower Clinical, Oklahoma City
  • Medical Research International, LLC, Oklahoma City
Ages 55 and older · All sexes · Updated Sep 28, 2026 · NCT06112418

A Study on the Efficacy of a Vaccine Against Influenza in Adults ≥65 Years of Age

RecruitingPhase 3Healthy volunteers welcome
  • GSK Investigational Site, Oklahoma City
Ages 65 and older · All sexes · Updated Sep 18, 2026 · NCT07805707

A Study to Evaluate Safety, Tolerability, and Immunogenicity of V350A and V350B in Healthy Participants (V350-001).

RecruitingPhase 1Healthy volunteers welcome
  • Lynn Health Science Institute ( Site 0010), Oklahoma City
Ages 12 to 30 · All sexes · Updated Sep 17, 2026 · NCT06655324

A Study to Learn About the Safety of an Expanded Pneumococcal Vaccine in Healthy Infants

RecruitingPhase 3Healthy volunteers welcome
  • Legacy Clinical Trials, Oklahoma City
42 Days – 98 Days · All sexes · Updated Sep 15, 2026 · NCT07573462

Identification and Validation of Blood-Based Biomarkers for Early Detection of Asymptomatic Lung Cancer in High-Risk Heavy Smokers

RecruitingObservational studyHealthy volunteers welcome
  • Site 101, Oklahoma City
Ages 30 to 80 · All sexes · Updated Sep 11, 2026 · NCT06816121

A Study of Aleniglipron in Adults With Obesity or Overweight and Type 2 Diabetes Mellitus (ACCOMPLISH-2)

RecruitingPhase 3Healthy volunteers welcome
  • ACCOMPLISH-2 Research Site, Yukon · 14 mi away
Ages 18 to 79 · All sexes · Updated Sep 11, 2026 · NCT07654374

The Vanguard Study: Testing a New Way to Screen for Cancer

RecruitingHealthy volunteers welcome
  • University of Oklahoma Health Sciences Center, Oklahoma City
Ages 45 to 75 · All sexes · Updated Sep 2, 2026 · NCT06995898

Limited Versus Extended Trophic Feeding (LET-FEED) Trial

RecruitingPhase 2/3Healthy volunteers welcome
  • University of Oklahoma, Oklahoma City
Ages 0 to 2 · All sexes · Updated Aug 17, 2026 · NCT06893939

Multidimensional Predictive Modeling to Understand Mechanisms of Exercise Response Heterogeneity in Older Adults (M3AX)

RecruitingHealthy volunteers welcome
  • Oklahoma Medical Research Foundation, Oklahoma City
Ages 60 and older · All sexes · Updated Aug 10, 2026 · NCT06507189

Self-collection for HPV Testing to Improve Cervical Cancer Prevention (SHIP) Trial (LMI-001-A-S04)

RecruitingHealthy volunteers welcome
  • University of Oklahoma Health Sciences Center, Oklahoma City
  • University of Oklahoma, Oklahoma City
Ages 25 and older · Women · Updated Jul 31, 2026 · NCT07281430

Outcomes in Simulated Endoscopy Training

RecruitingHealthy volunteers welcome
  • University of Oklahoma, Oklahoma City
Ages 22 to 50 · All sexes · Updated Jul 30, 2026 · NCT03495141

Efficacy of the Buzzy System on Pain and Fear Reduction in Elbow Fracture Pin Removal

RecruitingHealthy volunteers welcome
  • OU Health Children's, Oklahoma City
  • OU Health, Oklahoma City
Ages 3 to 10 · All sexes · Updated Jul 30, 2026 · NCT07520851

Motiva Implants® Post-Approval Study

RecruitingHealthy volunteers welcome
  • Jones Plastic Surgery, Oklahoma City
Ages 22 and older · Women · Updated Jul 17, 2026 · NCT06938399

Empowering Cessation ACS South Region

RecruitingPhase 2/3Healthy volunteers welcome
  • University of Oklahoma Health Campus, Oklahoma City
Ages 18 to 100 · All sexes · Updated May 11, 2026 · NCT06820034

Cigar Legislation and Regulation in Tobacco for the Young (Project CLARITY)

RecruitingHealthy volunteers welcome
  • University of Oklahoma Health Campus, Oklahoma City
Ages 18 to 24 · All sexes · Updated May 11, 2026 · NCT07162935

Use of CA125 and Complementary Biomarkers for the Early Detection of Ovarian Cancer in Low Risk Women

RecruitingHealthy volunteers welcome
  • University of Oklahoma Health Sciences Center, Oklahoma City
Ages 50 to 74 · Women · Updated May 6, 2026 · NCT00539162

Efficacy of a Smartphone-Based JITAI to Reduce Drinking Among Adults Experiencing Homelessness

RecruitingPhase 2/3Healthy volunteers welcome
  • University of Oklahoma Health Sciences Center, Oklahoma City
Ages 18 and older · All sexes · Updated May 1, 2026 · NCT06821295

A Culturally Tailored Smartphone Application for African American Smokers

RecruitingHealthy volunteers welcome
  • TSET Health Promotion Research Center, Oklahoma City
Ages 18 and older · All sexes · Updated May 1, 2026 · NCT05188287

Acellular Dermal Matrix Investigation in Breast Reconstruction

RecruitingHealthy volunteers welcome
  • Mercy Hospital, Oklahoma City
  • Mercy, Oklahoma City
Ages 22 and older · Women · Updated Apr 30, 2026 · NCT06456554

Postural Control in Adults

RecruitingHealthy volunteers welcome
  • University of Oklahoma Health Sciences Center, Oklahoma City
Ages 65 to 80 · All sexes · Updated Apr 28, 2026 · NCT07554118

Local Bisphosphonate Effect on Recurrence Rate in Extremity Giant Cell Tumor of Bone

RecruitingPhase 3Healthy volunteers welcome
  • University of Oklahoma, Oklahoma City
Ages 18 and older · All sexes · Updated Apr 22, 2026 · NCT03295981

The Effect of NAD Supplementation on Brain Vascular Health in Aging

RecruitingPhase 4Healthy volunteers welcome
  • University of Oklahoma Health Sciences Center, Oklahoma City
Ages 60 to 85 · All sexes · Updated Apr 1, 2026 · NCT05483465

Evaluating Whether an Educational Website Called Current Together After Cancer (CTAC) Improves Follow-up Care for Colorectal Cancer Survivors

RecruitingPhase 3Healthy volunteers welcome
  • Mercy Hospital Oklahoma City, Oklahoma City
Ages 18 and older · All sexes · Updated Mar 31, 2026 · NCT07018869

Postnatal Exercise to Activate Baby's Brown Fat

RecruitingHealthy volunteers welcome
  • Oklahoma University College of Medicine, Oklahoma City
Ages 18 to 45 · Women · Updated Mar 12, 2026 · NCT07467694

The Effect of Near-infrared Light Therapy on Brain Function and Cognition in Young and Older Adults

RecruitingHealthy volunteers welcome
  • University of Oklahoma Health Campus, Oklahoma City
Ages 21 to 85 · All sexes · Updated Feb 6, 2026 · NCT07209683

Binaural Cue Sensitivity in Children and Adults With Combined Electric and Acoustic Stimulation

RecruitingObservational studyHealthy volunteers welcome
  • Hearts for Hearing, Oklahoma City
Ages 5 and older · All sexes · Updated Jan 21, 2026 · NCT07356128

Attitudes and Perceptions Attitudes and Smoking Perceptions in the Real Environment -II

RecruitingHealthy volunteers welcome
  • TSET Health Promotion Research Center, Oklahoma City
Ages 18 to 34 · All sexes · Updated Aug 17, 2025 · NCT06668350

Safety and Efficacy of Brilaroxazine (RP5063) in Schizophrenia

RecruitingPhase 3Healthy volunteers welcome
  • Reviva site, Oklahoma City
Ages 18 to 65 · All sexes · Updated Dec 19, 2024 · NCT05184335

IN Midazolam vs IN Dexmedetomidine vs IN Ketamine During Minimal Procedures in Pediatric ED

RecruitingPhase 4Healthy volunteers welcome
  • University of Oklahoma Health Sciences Center, Oklahoma City
Ages 1 to 5 · All sexes · Updated Jun 28, 2024 · NCT05934669

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.