๐Ÿ”Ž Trials Near Me

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Pain clinical trials recruiting in the U.S.

207 studies for Pain are recruiting participants at sites across the United States.

Pain is a feeling triggered in the nervous system. You may feel it as a prick, tingle, sting, burn, or ache. Read about the causes and what can help.

Cities with the most studies

By state

Recently updated studies

Sociocultural & Biobehavioral Influences on Pain Expression and Assessment

RecruitingHealthy volunteers welcome
Ages 18 to 60 ยท All sexes ยท Updated Oct 2, 2026 ยท NCT03258580

Home-based Rehabilitation Intervention for Phantom Limb Pain in Veterans With Lower Limb Amputations

Recruiting
Ages 18 to 89 ยท All sexes ยท Updated Oct 2, 2026 ยท NCT06106984

Ketamine Pharmacokinetics and Pharmacodynamics for Postpartum Depression and Pain After Cesarean Delivery

RecruitingPhase 1Healthy volunteers welcome
Ages 18 and older ยท All sexes ยท Updated Oct 2, 2026 ยท NCT06767566

State-dependent Interoception, Value-based Decision-making, and Introspection

RecruitingHealthy volunteers welcome
Ages 18 to 55 ยท All sexes ยท Updated Oct 2, 2026 ยท NCT05666726

Neural and Psychological Mechanisms of Pain Perception

RecruitingHealthy volunteers welcome
Ages 18 to 50 ยท All sexes ยท Updated Oct 2, 2026 ยท NCT02446262

An Open-Label, Safety and Efficacy Study of Cebranopadol in Participants With Acute Pain With Surgical or Non-Surgical Origin

RecruitingPhase 3
Ages 18 to 75 ยท All sexes ยท Updated Sep 30, 2026 ยท NCT07845071

Binaural Beats for Postoperative Pain and Anxiety Reduction

Recruiting
Ages 18 to 99 ยท All sexes ยท Updated Sep 30, 2026 ยท NCT07437469

Pain and Smoking Study 2.0: A Randomized Clinical Trial of Smoking Cessation Among Veterans With Chronic Pain

Recruiting
Ages 18 and older ยท All sexes ยท Updated Sep 29, 2026 ยท NCT06442514

Behavioral Economic & Staffing Strategies in the ICU

Recruiting
Ages 19 and older ยท All sexes ยท Updated Sep 29, 2026 ยท NCT06184945

Feasibility of a Mindfulness Intervention for Endometriosis Surgery

Recruiting
Ages 18 and older ยท Women ยท Updated Sep 29, 2026 ยท NCT06141720

Chronic Postsurgical Pain

RecruitingObservational study
Ages 5 to 17 ยท All sexes ยท Updated Sep 25, 2026 ยท NCT05764681

Enhanced Pain Coping in Cancer (EPIC): A Study of Managing Treatment-Related Joint Pain in Breast Cancer Survivors

RecruitingPhase 2
Ages 18 and older ยท Women ยท Updated Sep 22, 2026 ยท NCT06728579

Transcutaneous Electrical Nerve Stimulation for Pain Mitigation During Intrauterine Device Placement

Recruiting
Ages 18 and older ยท Women ยท Updated Sep 18, 2026 ยท NCT06991075

Functional Neuroimaging to Detect the Neural Signatures of the Unpleasantness of Pain and Effort

RecruitingEarly phase 1
Ages 18 to 50 ยท All sexes ยท Updated Sep 18, 2026 ยท NCT06472622

Impact of Art Therapy on Self-Reported Pain and Anxiety Scores of Patients Waiting to Be Seen in the Emergency Department

RecruitingHealthy volunteers welcome
Ages 18 and older ยท All sexes ยท Updated Sep 17, 2026 ยท NCT05540106

Feasibility Study of a Guided Imagery Therapy Mobile Application for Functional Abdominal Pain Disorders in Children

Recruiting
Ages 7 to 12 ยท All sexes ยท Updated Sep 17, 2026 ยท NCT07222943

Transcutaneous Vagus Nerve Stimulation in SLE

RecruitingPhase 2
Ages 18 and older ยท All sexes ยท Updated Sep 17, 2026 ยท NCT06987565

Clinical and Scientific Assessment of Pain and Painful Disorders

RecruitingObservational studyHealthy volunteers welcome
Ages 12 to 120 ยท All sexes ยท Updated Sep 16, 2026 ยท NCT02707029

Brief Mindfulness Intervention for Pain Before an In-clinic Orthopedic Procedure

Recruiting
Ages 18 and older ยท All sexes ยท Updated Sep 15, 2026 ยท NCT06471075

Transdiagnostic Cognitive Biomarkers

RecruitingHealthy volunteers welcome
Ages 18 and older ยท All sexes ยท Updated Sep 15, 2026 ยท NCT04864080

Nebulized Ketamine to Nebulized Fentanyl for Treating Acute Painful Conditions in the ED

RecruitingPhase 4
Ages 18 to 120 ยท All sexes ยท Updated Sep 15, 2026 ยท NCT06364540

Vagus Nerve Stimulation(VNS) As Treatment For Fibromyalgia Patients

Recruiting
Ages 18 to 80 ยท All sexes ยท Updated Sep 14, 2026 ยท NCT06009159

Post-stroke Pain tAN-fMRI

Recruiting
Ages 18 to 80 ยท All sexes ยท Updated Sep 11, 2026 ยท NCT07144436

RELIEF - A Global Prospective Observational Post-Market Study to Evaluate Long-Term Effectiveness of Neurostimulation Therapy for Pain

RecruitingObservational study
Ages 18 and older ยท All sexes ยท Updated Sep 11, 2026 ยท NCT01719055

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.