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Pancreatic Cancer clinical trials in Pittsburgh, PA

20 studies for Pancreatic Cancer are looking for participants at sites in and around Pittsburgh (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

Testing the Safety and Tolerability of the Anti-cancer Drugs Trastuzumab Deruxtecan and Neratinib for Cancers With Changes in the HER2 Gene

RecruitingPhase 1
  • UPMC Hillman Cancer Center, Pittsburgh
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT05372614

Distance-Based Exercise to Preserve Function and Prevent Disability

Recruiting
  • UPMC Hillman Cancer Center, Pittsburgh
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT07059884

Pancreatic Cancer Detection Consortium

RecruitingObservational studyHealthy volunteers welcome
  • AHN Cancer Institute at Allegheny General Hospital, Pittsburgh
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT06388967

Study of Daraxonrasib (RMC-6236) in Patients With Resected Pancreatic Ductal Adenocarcinoma (PDAC)

RecruitingPhase 3
  • UPMC Hillman Cancer Center, Pittsburgh
Ages 18 and older · All sexes · Updated Sep 23, 2026 · NCT07252232

A Study to Evaluate Chemotherapy With or Without INCB161734 in Previously Untreated, KRAS G12D-Mutated Metastatic Pancreatic Ductal Adenocarcinoma

RecruitingPhase 3
  • Investigative Site US056, Pittsburgh
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07522073

A Study to Evaluate the Effectiveness and Safety of Setidegrasib, Given With Either mFOLFIRINOX or NALIRIFOX Chemotherapies, in People With Pancreatic Cancer

RecruitingPhase 3
  • AGH Singer Research Institute, Pittsburgh
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07409272

Study of Elironrasib and Daraxonrasib as Monotherapies and Combination Therapy in Participants With Advanced KRAS G12C Mutant Solid Tumors

RecruitingPhase 1/2
  • Allegheny Health Network, Pittsburgh
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT06128551

Pancreatic Cancer Detection Consortium (PCDC) Prospective Cohorts

RecruitingObservational study
  • University of Pittsburgh, Pittsburgh
Ages 18 and older · All sexes · Updated Sep 21, 2026 · NCT06271291

Biospecimen Collection to Identify Gene Mutations for High Risk Pancreatic Cancer in Pediatric Patients, INSPPIRE 2 Study

RecruitingObservational study
  • Children's Hospital of Pittsburgh of UPMC, Pittsburgh
Up to age 17 · All sexes · Updated Sep 11, 2026 · NCT06651580

Comparing the Clinical Impact of Pancreatic Cyst Surveillance Programs and Associated Biomarkers

RecruitingObservational study
  • Bryn Mawr Hospital, Bryn Mawr · 11 mi away
Ages 50 to 75 · All sexes · Updated Sep 4, 2026 · NCT04239573

Testing the Addition of a New Anti-cancer Drug, M3814 (Peposertib), to the Usual Radiotherapy in Patients With Locally Advanced Pancreatic Cancer

RecruitingPhase 1/2
  • UPMC Hillman Cancer Center, Pittsburgh
Ages 18 and older · All sexes · Updated Sep 1, 2026 · NCT04172532

Testing Higher Dose Radiation Therapy for Locally Advanced Pancreatic Cancer

RecruitingPhase 3
  • Allegheny General Hospital, Pittsburgh
  • West Penn Hospital, Pittsburgh
  • Jefferson Hospital, Jefferson Hills · 11 mi away
  • and 1 more
Ages 18 and older · All sexes · Updated Aug 25, 2026 · NCT06958328

Pancreatic Cancer Early Detection Consortium

RecruitingObservational studyHealthy volunteers welcome
  • University of Pittsburgh Medical Center (Upmc), Pittsburgh
Ages 18 to 90 · All sexes · Updated Jul 22, 2026 · NCT04970056

Study of CX-5461 in Patients With Solid Tumours and BRCA1/2, PALB2 or Homologous Recombination Deficiency (HRD) Mutation

RecruitingPhase 1
  • UPMC Hillman Cancer Center, Pittsburgh
Ages 18 and older · All sexes · Updated Jun 8, 2026 · NCT04890613

Acoustic Cluster Therapy (ACT) With Chemotherapy for the Treatment of Locally Advanced Pancreatic Cancer

RecruitingPhase 2
  • Allegheny General Hospital, Pittsburgh
Ages 18 and older · All sexes · Updated Apr 3, 2026 · NCT06850623

The MOMENTUM Study: The Multiple Outcome Evaluation of Radiation Therapy Using the MR-Linac Study

RecruitingObservational study
  • Allegheny Health Network, Pittsburgh
Ages 18 and older · All sexes · Updated Mar 5, 2026 · NCT04075305

A Phase II Nationwide, Fully Decentralized, Telemedicine Study of Pemigatinib in Adult Patients With Advanced or Metastatic Pancreatic Cancer With FGFR Genetic Alterations

RecruitingPhase 2
  • Ohio State University-Telemedicine, Pittsburgh
Ages 18 and older · All sexes · Updated Feb 17, 2026 · NCT06906562

Pancreatic Adenocarcinoma Gene Environment Risk Study

RecruitingObservational studyHealthy volunteers welcome
  • University of Pittsburgh, Pittsburgh
Ages 18 and older · All sexes · Updated Nov 19, 2025 · NCT00912717

The Cancer of the Pancreas Screening-5 CAPS5)Study

RecruitingPhase 3
  • University of Pittsburgh, Pittsburgh
Ages 18 and older · All sexes · Updated Oct 9, 2025 · NCT02000089

Study of Safety and Tolerability of BCA101 Monotherapy and in Combination Therapy in Patients With EGFR-driven Advanced Solid Tumors

RecruitingPhase 1
  • UPMC Hillman Cancer Center, Pittsburgh
Ages 18 and older · All sexes · Updated Aug 15, 2025 · NCT04429542

About Pancreatic Cancer

The pancreas is a gland behind your stomach that produces insulin. Pancreatic cancer is hard to catch early. Find out about risk factors and symptoms.

More about Pancreatic Cancer on MedlinePlus

Pancreatic Cancer trials in other cities

Other studies in Pittsburgh

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.