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Urothelial (Transitional Cell) Carcinoma clinical trials in Chicago, IL

14 studies for Urothelial (Transitional Cell) Carcinoma are looking for participants at sites in and around Chicago (within about 30 miles). Open a study to see who can join and how to contact the study team.

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Study of Zanzalintinib in Combination With Immuno-Oncology or Other Agents in Participants With Solid Tumors

RecruitingPhase 1
  • Exelixis Clinical Site #26, Chicago
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT05176483

A Study Comparing the Combination of Pembrolizumab and Sacituzumab Govitecan-hziy Versus Standard of Care in the Treatment of Advanced Urothelial Cancer

RecruitingPhase 3
  • University of Illinois, Chicago
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT06524544

Testing the Effectiveness of Two Immunotherapy Drugs (Nivolumab and Ipilimumab) With One Anti-cancer Targeted Drug (Cabozantinib) for Rare Genitourinary Tumors

RecruitingPhase 2
  • Rush MD Anderson Cancer Center, Chicago
  • University of Chicago Comprehensive Cancer Center, Chicago
Ages 18 and older · All sexes · Updated Sep 30, 2026 · NCT03866382

uTRACT Jelmyto Registry: A Registry of Patients With Upper Tract Urothelial Cancer (UTUC) Treated With Jelmyto

RecruitingObservational study
  • Northwestern University, Chicago
Ages 18 and older · All sexes · Updated Sep 29, 2026 · NCT05874921

A Substudy of Investigational Agents in Programmed Cell Death-1/Ligand 1 (PD-1/L1) Refractory Locally Advanced or Metastatic Urothelial Carcinoma (mUC) (MK-3475-04A)

RecruitingPhase 1/2
  • University of Chicago Medical Center ( Site 1037), Chicago
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT05562830

A Study of Vepugratinib (LY3866288) in Participants With Cancer in the Urinary Tract

RecruitingPhase 3
  • University of Illinois at Chicago, Chicago
  • University of Chicago Medical Center, Chicago
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07218380

Open Label Study to Evaluate BL-M07D1 in HER2 Expressing Malignant Solid Tumors

RecruitingPhase 1
  • University of Illinois Cancer Center, Chicago
  • University of Chicago Medicine, Chicago
Ages 18 and older · All sexes · Updated Sep 10, 2026 · NCT06293898

A Study of Disitamab Vedotin Alone or With Pembrolizumab in Urothelial Cancer That Expresses HER2

RecruitingPhase 2
  • UChicago Medicine - River East, Chicago
  • University of Chicago Medical Center, Chicago
Ages 18 and older · All sexes · Updated Jul 22, 2026 · NCT04879329

A Study to Investigate ALE.P03 as Monotherapy in Adult Patients With Selected Advanced or Metastatic CLDN1+ Solid Tumors

RecruitingPhase 1/2
  • The University of Chicago Medical Center - Oncology, Chicago
Ages 18 and older · All sexes · Updated Jul 2, 2026 · NCT07169734

Intravesical Photodynamic Therapy ("PDT") in BCG-Unresponsive/Intolerant Non-Muscle Invasive Bladder Cancer ("NMIBC") Patients

RecruitingPhase 2
  • Site 02-012 - University of Chicago, Chicago
Ages 18 and older · All sexes · Updated Nov 24, 2025 · NCT03945162

SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

RecruitingObservational study
  • Massive Bio SYNERGY-AI site, Chicago
All ages · All sexes · Updated Oct 28, 2025 · NCT03452774

Prospective Validation Study of High Volume Urine DNA Testing in Individuals With Suspicion of Urothelial Cancer

RecruitingObservational study
  • Jesse Brown Department Of Veterans Affairs Medical Center, Chicago
Ages 18 to 100 · All sexes · Updated Oct 10, 2025 · NCT06310759

A Study of NX-1607 in Adults With Advanced Malignancies

RecruitingPhase 1
  • University of Chicago, Chicago
Ages 18 and older · All sexes · Updated Sep 9, 2025 · NCT05107674

CPI-613 (Devimistat) in Combination With Hydroxychloroquine and 5-fluorouracil or Gemcitabine in Treating Patients With Advanced Chemorefractory Solid Tumors

RecruitingPhase 2
  • Northwestern University, Chicago
Ages 18 and older · All sexes · Updated Mar 10, 2023 · NCT05733000

Urothelial (Transitional Cell) Carcinoma trials in other cities

Other studies in Chicago

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.