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Acute Myeloid Leukemia clinical trials in Charlotte, NC

16 studies for Acute Myeloid Leukemia are looking for participants at sites in and around Charlotte (within about 30 miles). Open a study to see who can join and how to contact the study team.

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MYELOMATCH: A Screening Study to Assign People With Myeloid Cancer to a Treatment Study or Standard of Care Treatment Within myeloMATCH (MyeloMATCH Screening Trial)

RecruitingPhase 2
  • Carolinas Medical Center/Levine Cancer Institute, Charlotte
  • Novant Health Presbyterian Medical Center, Charlotte
Ages 18 and older · All sexes · Updated Oct 5, 2026 · NCT05564390

Comparing Cytarabine + Daunorubicin Therapy Versus Cytarabine + Daunorubicin + Venetoclax Versus Venetoclax + Azacitidine in Younger Patients With Intermediate Risk AML (A MyeloMATCH Treatment Trial)

RecruitingPhase 2
  • Carolinas Medical Center/Levine Cancer Institute, Charlotte
  • Novant Health Presbyterian Medical Center, Charlotte
Ages 18 to 59 · All sexes · Updated Sep 28, 2026 · NCT05554393

A Study of Bleximenib, Venetoclax and Azacitidine For Treatment of Participants With Newly Diagnosed Acute Myeloid Leukemia (AML)

RecruitingPhase 3
  • Atrium Health, Charlotte
  • Novant Health Charlotte, Charlotte
  • Carolina Oncology Specialists, Charlotte
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06852222

Comparing New Treatments for People With Newly Diagnosed Acute Myeloid Leukemia That Has an IDH2 Gene Change (A MyeloMATCH Treatment Trial)

RecruitingPhase 2
  • Carolinas Medical Center/Levine Cancer Institute, Charlotte
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT06672146

Testing New Therapies for Patients With Acute Myeloid Leukemia Who Are Newly Diagnosed and Have Not Yet Started Treatment (A MyeloMATCH Treatment Trial)

RecruitingPhase 2
  • Carolinas Medical Center/Levine Cancer Institute, Charlotte
Ages 18 to 59 · All sexes · Updated Sep 22, 2026 · NCT05554406

Venetoclax and HMA Treatment of Older and Unfit Adults With FLT3 Mutated Acute Myeloid Leukemia (AML) (A MyeloMATCH Treatment Trial)

RecruitingPhase 2
  • Carolinas Medical Center/Levine Cancer Institute, Charlotte
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT06317649

A Study to Compare Standard Chemotherapy to Therapy With CPX-351 and/or Gilteritinib for Patients With Newly Diagnosed AML With or Without FLT3 Mutations

RecruitingPhase 3
  • Carolinas Medical Center/Levine Cancer Institute, Charlotte
  • Novant Health Presbyterian Medical Center, Charlotte
6 Months – 21 Years · All sexes · Updated Sep 17, 2026 · NCT04293562

Evaluation of Two Dose Levels of Quizartinib as Maintenance in FLT3-ITD (+) Acute Myeloid Leukemia Patients in Complete Remission

RecruitingPhase 2
  • Novant Health Clinical Research, Charlotte
Ages 18 and older · All sexes · Updated Sep 16, 2026 · NCT06824168

A Longitudinal Multi-Center Molecular Biomarker Discovery Registry for Patients With Hematologic Malignancies

RecruitingObservational study
  • Novant Health Weisiger Cancer Institute, Charlotte
Ages 0 and older · All sexes · Updated Sep 2, 2026 · NCT07154823

The Pediatric Acute Leukemia (PedAL) Screening Trial - A Study to Test Bone Marrow and Blood in Children With Leukemia That Has Come Back After Treatment or Is Difficult to Treat - A Leukemia & Lymphoma Society and Children's Oncology Group Study

RecruitingPhase 1/2
  • Carolinas Medical Center/Levine Cancer Institute, Charlotte
  • Novant Health Presbyterian Medical Center, Charlotte
Up to age 22 · All sexes · Updated Aug 25, 2026 · NCT04726241

Safety and Tolerability of Ziftomenib Combinations in Patients With Relapsed/Refractory Acute Myeloid Leukemia

RecruitingPhase 1
  • Atrium Health Levine Cancer Center, Charlotte
Ages 18 and older · All sexes · Updated Aug 20, 2026 · NCT06001788

Toxicity Genetic Determinants and Response to Azacitidine and Venetoclax in AML

RecruitingObservational study
  • Levine Cancer Institute, Charlotte
Ages 18 and older · All sexes · Updated Jul 24, 2026 · NCT06580106

ONC-LEUK-2406: The Impact of Systematic Financial Navigation in Acute Myeloid Leukemia

Recruiting
  • Levine Cancer Insitute, Charlotte
Ages 18 to 64 · All sexes · Updated Jul 23, 2026 · NCT06945042

A Multicenter Access and Distribution Protocol for Unlicensed Cryopreserved Cord Blood Units (CBUs)

RecruitingObservational study
  • Levine Children's Hospital, Charlotte
All ages · All sexes · Updated Jul 6, 2026 · NCT01351545

Clinical Study of ARD103 CAR-T Therapy for Patients With R/R AML or MDS

RecruitingPhase 1/2
  • Novant Health Cancer Institute, Charlotte
Ages 18 and older · All sexes · Updated Dec 10, 2025 · NCT06680752

About Acute Myeloid Leukemia

Acute Myeloid Leukemia (AML) is a cancer of the white blood cells. AML usually gets worse quickly if it is not treated. Read more.

More about Acute Myeloid Leukemia on MedlinePlus

Acute Myeloid Leukemia trials in other cities

Other studies in Charlotte

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.