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Cardiovascular Disease clinical trials in Nashville, TN

18 studies for Cardiovascular Disease are looking for participants at sites in and around Nashville (within about 30 miles). Open a study to see who can join and how to contact the study team.

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Inclisiran Versus Placebo for the Prevention of Major Adverse Cardiovascular and Limb Events in Patients Undergoing Percutaneous Coronary Intervention or Peripheral Endovascular Intervention

RecruitingPhase 4
  • TriStar Centennial Medical Center, Nashville
Ages 18 and older · All sexes · Updated Oct 5, 2026 · NCT06909565

ELEVATE-HFpEF Clinical Study

Recruiting
  • Saint Thomas Research Institute, Nashville
Ages 40 and older · All sexes · Updated Oct 2, 2026 · NCT06678841

Improving Veteran Referral to Cardiac Rehabilitation

Recruiting
  • Tennessee Valley Healthcare System Nashville Campus, Nashville, TN, Nashville
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT07079358

Product Surveillance Registry

RecruitingObservational study
  • Nashville, Nashville
All ages · All sexes · Updated Sep 18, 2026 · NCT01524276

Transcatheter Mitral Valve Replacement With the Medtronic Intrepid™ TMVR System in Patients With Severe Symptomatic Mitral Regurgitation.

Recruiting
  • Vanderbilt University Medical Center, Nashville
Ages 18 and older · All sexes · Updated Sep 15, 2026 · NCT03242642

An Open Label Extension (OLE) Study (Following Completion of CTQJ230A12301) to Evaluate Long-term Safety and Tolerability of Pelacarsen (TQJ230)

RecruitingPhase 3
  • Vanderbilt Univ Medi Cen, Nashville
Ages 18 to 100 · All sexes · Updated Sep 4, 2026 · NCT07517263

Safety and Performance Assessment of the Sphere-9™ Catheter and Affera™ Ablation System for the Treatment of Ventricular Tachycardia (Sphere-9 VT EFS)

Recruiting
  • Vanderbilt University Medical Center, Nashville
Ages 18 to 85 · All sexes · Updated Sep 3, 2026 · NCT06703489

Pragmatic Evaluation of Events And Benefits of Lipid-lowering in Older Adults

RecruitingPhase 4Healthy volunteers welcome
  • Meharry Medical College, Nashville
  • Nashville VA Medical Center, Nashville
  • Vanderbilt University Medical Center, Nashville
Ages 75 and older · All sexes · Updated Sep 1, 2026 · NCT04262206

Microbiome Metabolites and Alcohol in HIV to Reduce CVD RCT

RecruitingPhase 2
  • Vanderbilt University Medical Center, Nashville
Ages 18 to 89 · All sexes · Updated Aug 27, 2026 · NCT05288790

A Phase III Study of AZD0780 on Major Adverse CV Events in Patients With a History of ASCVD Events or at High Risk for a First Event

RecruitingPhase 3
  • Research Site, Nashville
Ages 18 and older · All sexes · Updated Aug 24, 2026 · NCT07000357

OCEAN(a)-PreEvent - Olpasiran Trials of Cardiovascular Events And LipoproteiN(a) Reduction to Prevent First Major Cardiovascular Events

RecruitingPhase 3
  • Ascension Saint Thomas, Nashville
Ages 50 to 105 · All sexes · Updated Aug 21, 2026 · NCT07136012

Global Paradise System US Post Approval Study

RecruitingObservational study
  • Ascension Saint Thomas, Nashville
Ages 18 and older · All sexes · Updated Aug 12, 2026 · NCT06297291

PROACTIVE-HF-2 Trial Heart Failure NYHA Class II and III

Recruiting
  • Vanderbilt, Nashville
Ages 18 and older · All sexes · Updated Jun 29, 2026 · NCT05934487

GLP-1 Receptor Agonists to Decrease Ethanol and CVD Risk in HIV

RecruitingPhase 2
  • Vanderbilt University Medical Center, Nashville
Ages 18 to 89 · All sexes · Updated May 26, 2026 · NCT07221214

The EMPOWER Trial - The Carillon Mitral Contour System® in Treating Heart Failure With FMR

Recruiting
  • Centennial Medical Center, Nashville
Ages 18 and older · All sexes · Updated Apr 13, 2026 · NCT03142152

Randomized Trial of SGLT2i in Heart Transplant Recipients

RecruitingPhase 4
  • Tennessee Valley Healthcare System Nashville Campus, Nashville, TN, Nashville
Ages 18 and older · All sexes · Updated Jan 22, 2026 · NCT06625073

Gut Microbiota in Metabolic Surgery

RecruitingObservational study
  • Vanderbilt_University MC, Nashville
Ages 21 to 65 · All sexes · Updated Nov 4, 2025 · NCT05000996

MagicTouch for Treatment of In-Stent Restenosis in Coronary Artery Lesions

Recruiting
  • Centennial Medical Center, Nashville
Ages 18 to 110 · All sexes · Updated Feb 25, 2025 · NCT05908331

Cardiovascular Disease trials in other cities

Other studies in Nashville

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.